L-3-(3,4-Dihydroxyphenyl)-2-methylalanine Ethyl Ester Hydrochloride
[The hydrochloride salt form of methyldopa, a phenylalanine derivate and aromatic amino acid decarboxylase inhibitor with antihypertensive activity. Methyldopa is a prodrug and is metabolized in the central nervous system. The antihypertensive action of methyldopa seems to be attributable to its conversion into alpha-methylnorepinephrine, which is a potent alpha-2 adrenergic agonist that binds to and stimulates potent central inhibitory alpha-2 adrenergic receptors. This results in a decrease in sympathetic outflow and decreased blood pressure. ( NCI )]
UMLS (NCI) C0304527- Organic Chemical
- Pharmacologic Substance
Relation/PAR: METHYLDOPATE
Relation/CHD: METHYLDOPATE HYDROCHLORIDE 50 MG/ML
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