[A murine IgG2a monoclonal antibody directed against a 48 kDa antigen expressed on the cell surface of normal and malignant gastrointestinal epithelium. MoAb D6.12 has been shown to induce antibody-dependent cell-mediated cytotoxicity (ADCC). This MoAb, either alone or in combination with other immunotherapeutic agents, may have possible diagnostic or therapeutic applications in gastrointestinal cancers. ( NCI )]
UMLS (NCI) C1134661MoAb D612
Monoclonal Antibody D6.12
- Amino Acid, Peptide, or Protein
- Pharmacologic Substance
- Immunologic Factor