N-(2-Dimethylaminopropyl-1)phenothiazine Hydrochloride

[The hydrochloride salt form of promethazine, a phenothiazine derivative with antihistaminic, sedative and antiemetic properties. Promethazine hydrochloride selectively blocks peripheral H1 receptors thereby diminishing the effects of histamine on effector cells. Promethazine hydrochloride also blocks the central histaminergic receptors, thereby depressing the reticular system causing sedative and hypnotic effects. In addition, promethazine hydrochloride also has centrally acting anticholinergic properties and probably mediates nausea and vomiting by acting on the medullary chemoreceptive trigger zone. ( NCI )]

UMLS (NCI) C0546876

Organic Chemical
Pharmacologic Substance

Relation/PAR: PROMETHAZINE

Relation/CHD: PROMETHAZINE HYDROCHLORIDE 25 MG
PROMETHAZINE HYDROCHLORIDE 6.25 MG/5ML
PROMETHAZINE HYDROCHLORIDE 625 MG/5ML
PROMETHAZINE HYDROCHLORIDE 25 MG/ML
PROMETHAZINE HYDROCHLORIDE 50 MG/ML
PROMETHAZINE HYDROCHLORIDE 5 MG
PROMETHAZINE HYDROCHLORIDE 6.25 MG
PROMETHAZINE HYDROCHLORIDE 12.5 MG
PROMETHAZINE HYDROCHLORIDE 50 MG
PROMETHAZINE HYDROCHLORIDE 25 MG/5ML
PROMETHAZINE HYDROCHLORIDE 5 MG/5ML
PROMETHAZINE HYDROCHLORIDE 6.2 MG

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