NABILONE
[A synthetic cannabinoid and dibenzopyrane derivative with anti-emetic activity. Although the mechanism of action has not been fully elucidated yet, it has been suggested that nabilone is a highly selective and strong agonist for the cannabinoid receptors CB1 and CB2, both of which are coupled to Gi/o proteins. The CB1 receptors are expressed predominantly in central and peripheral neurons and receptor stimulation has been implicated in the reduction of chemotherapy-induced nausea. ( NCI )]
UMLS (NCI) C0068333- Organic Chemical
- Pharmacologic Substance
Relation/PAR: [GA700] ANTIEMETICS
(-)-.DELTA.9-Tetrahydrocannabinol
(-)-.DELTA.9-Tetrahydrocannabinol
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