NMI

1. [This gene plays a role in transcriptional regulation through the signal transduction activating transcription pathway or STAT pathway. ( NCI )]
   UMLS (NCI) C1334885
   
   NMI Gene
   N-MYC (and STAT) Interactor Gene
    

   Gene or Genome
   

2. [NMYC interactor (NMI) is a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias. (LocusLink) ( NCI )]
   UMLS (NCI) C1334888
   
   NMYC and STAT Interactor
   NMYC Interactor
    

   Amino Acid, Peptide, or Protein

   Biologically Active Substance