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UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
O O- O0 O1 O2 O3 OA OB OC OD OE OF OG OH OI OJ OK OL OM ON OO OP OR OS OT OU OV OW OX OY OZ
OVA OVE OVI OVL OVO OVR OVU

OVA BiP Peptide

[A 19 amino acids hybrid peptide antigen with immune adjuvant property. OVA-BiP peptide consists of 8 amino acids from ovalbumin joined via a tripeptide linker to a stretch of 8 amino acids, the minimum binding domain of BiP (immunoglobulin heavy chain-binding protein, aka grp78), a member of the heat shock protein (hsp) 70 family. As a chaperon, BiP binds to newly synthesized, unfolded mu immnoglobulin heavy chain prior to its assembly with light chain in the endoplasmic reticulum. In conjunction with a tumor antigen, this hybrid peptide is used to potentiate antigen presentation and consequently prime cytotoxic T lymphocyte responses. ( NCI )]
UMLS (NCI) C0879487
OVA-BiP Hybrid Peptide
 
Amino Acid, Peptide, or Protein
Pharmacologic Substance

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