P P- P0 P1 P2 P3 P4 P5 P6 P7 P8 P9 PA PB PC PD PE PF PG PH PI PK PL PM PN PO PP PQ PR PS PT PU PV PW PX PY
PPP1A
[Expressed by human PPP1CA Gene (PP1 Family), cytoplasmic Protein Phosphatase 1 Catalytic Subunit Alpha is one of 3 catalytic subunits (A, B, or C) of PP1 folded by IPP2 and GSK3 and then complexed to various targeting or regulatory subunits. PPP1CA is inhibited by IPP1 and IPP2. Protein phosphorylation is crucial in the regulation of many cellular functions; the level of phosphorylation is controlled by the actions of opposing kinases and phosphatases. PP1 is a major serine/threonine-protein phosphatase essential for cell division, regulation of glycogen metabolism, muscle contractility protein synthesis, regulation of ionic conductances, and long-term synaptic plasticity/memory. PPP1CA may dephosphorylate postsynaptic density-associated Ca++/calmodulin dependent protein kinase II. (NCI) ( NCI )]
UMLS (NCI) C1335536PPP1CA
Protein Phosphatase 1 Catalytic Subunit Alpha
Serine/Threonine Protein Phosphatase PP1-Alpha 1 Catalytic Subunit
Protein Phosphatase 1 Catalytic Subunit Alpha
Serine/Threonine Protein Phosphatase PP1-Alpha 1 Catalytic Subunit
- Amino Acid, Peptide, or Protein
- Enzyme
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