[A peptide vaccine containing the prostate specific antigen (PSA) with potential antineoplastic activity. PSA, a glycoprotein secreted by prostatic epithelial and ductal cells, is overexpressed in prostate cancer cells and is used as a tumor marked for both diagnosis and treatment evaluation. Vaccination with PSA peptide vaccine may produce anti-PSA antibodies as well as elicit a cytotoxic T-cell (CTL) response against prostate cancer cells expressing this antigen, thereby, decreasing tumor cell growth. ( NCI )]
UMLS (NCI) C0796406 - Amino Acid, Peptide, or Protein
- Pharmacologic Substance
- Immunologic Factor