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Peptide 946-Tetanus Peptide Conjugate Melanoma Vaccine
[A melanoma peptide vaccine complexed with tetanus toxoid with potential antineoplastic activity. Peptide 946 contains a melanoma-specific epitope recognized by melanoma-specific cytotoxic T lymphocytes (CTL). In addition to the peptide 946 sequence, this vaccine contains tetanus toxoid, a protein known to stimulate the induction of CD4+ T lymphocytes, and thereby enhance antigen processing and presentation. Vaccination with the peptide 946-tetanus conjugate melanoma vaccine may produce antibodies as well as elicit a cytotoxic T lymphocyte (CTL) response in tumor cells expressing the 946 epitope, thereby, decreasing tumor cell growth. ( NCI )]
UMLS (NCI) C0677987- Amino Acid, Peptide, or Protein
- Pharmacologic Substance
- Immunologic Factor
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