Quinapril Hydrochloride
[The hydrochloride salt form of quinapril, a prodrug and non-sulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. Quinapril is hydrolized into its active form quinaprilat, which binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This abolishes the potent vasoconstrictive actions of angiotensin II and leads to vasodilatation. Quinapril also causes a decrease in angiotensin II-induced aldosterone secretion by the adrenal cortex, thereby promoting diuresis and natriuresis, and increases bradykinin levels. ( NCI )]
UMLS (NCI) C0770920QUINAPRIL HYDROCHLORIDE PREPARATION
- Organic Chemical
- Pharmacologic Substance
Relation/PAR: QUINAPRIL
Relation/CHD: QUINAPRIL HYDROCHLORIDE 5 MG
QUINAPRIL HYDROCHLORIDE 10 MG
QUINAPRIL HYDROCHLORIDE 20 MG
QUINAPRIL HYDROCHLORIDE 40 MG
QUINAPRIL HYDROCHLORIDE 10 MG
QUINAPRIL HYDROCHLORIDE 20 MG
QUINAPRIL HYDROCHLORIDE 40 MG
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