UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
R R R- R0 R1 R2 R3 R4 RA RB RC RD RE RF RG RH RI RK RM RN RO RP RQ RR RS RT RU RV RW RX RY
RA RA- RA4 RAB RAC RAD RAE RAF RAG RAI RAL RAM RAN RAP RAR RAS RAT RAU RAV RAY RAZ

RAD54B

[Highly expressed in testis and spleen by human RAD54B Gene (SNF2/SWI2 Family), the two isoforms of 910-aa 100-kD nucleoplasmic RAD54B Homolog exhibit significant homology to RAD54 and motifs similar to DNA and RNA helicases. RAD54B binds to double-stranded DNA and displays DNA-associated ATPase activity. RAD54B appears to associate indirectly with RAD51 through its N-terminal domain and may colocalize with RAD54 and BRCA1. Part of a complex involved in meiotic and mitotic homologous DNA recombination repair, RAD54B plays a critical role in targeted integration and recombination in concert with other RAD52 epistasis group members without affecting cell growth, sensitivity to DNA damaging agents, or sister chromatid exchange. (NCI) ( NCI )]
UMLS (NCI) C1447487
RAD54B Homolog
RAD54B Protein
 
Amino Acid, Peptide, or Protein
Biologically Active Substance

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