[Expressed by human SRP19 Gene (SRP19 Family), 144-aa cytoplasmic Signal Recognition Particle 19kDa, with 7 C-terminal Lys interrupted by 2 Gly residues, is involved in signal-recognition-particle assembly (SRP). Monomeric SRP19 mediates binding of the monomeric 54-kDa subunit and binds directly to the SRP 7SLRNA helix 6 stem-loop structure. Mediating signal recognition, translational arrest, and ER targeting by docking protein interaction, the SRP complex consists of a 7SLRNA and SRP9, SRP14, SRP19, SRP54, SRP68, and SRP72 protein subunits. SRP9/SRP14 (Alu domain) and SRP68/SRP72 (S domain) bind to 7SLRNA as heterodimers. (NCI) ( NCI )]
UMLS (NCI) C1335958SRP19
- Amino Acid, Peptide, or Protein
- Biologically Active Substance