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Synchrotope TA2M Plasmid DNA Vaccine
[A recombinant plasmid DNA vaccine encoding epitopes of tyrosinase with potential antineoplastic activity. Synchrotope TA2M vaccine contains a plasmid encoding 2 epitopes (amino acid sequences 207-216 and 1-17) of tyrosinase, a protein frequently expressed by melanoma cells. Vaccination with the TA2M plasmid DNA vaccine may induce the production of anti-tyrosinase antibodies as well as elicit a cytotoxic T-lymphocyte (CTL) response against tyrosinase-expressing tumor cells, resulting in decreased tumor growth. ( NCI )]
UMLS (NCI) C1134471- Pharmacologic Substance
- Immunologic Factor
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