T T T, T- T0 T1 T2 T3 T4 T9 TA TB TC TD TE TF TG TH TI TJ TK TL TM TN TO TP TQ TR TS TT TU TV TW TY TZ
TIL
[Ubiquitously expressed (highest in spleen, ovary, leukocytes, thymus, and small intestine) by human TLR1 Gene (TLR family), 786-aa 90-kDa (precursor) type I transmembrane Toll-Like Receptor 1 contains a TIR domain and 8 LRR repeats and has a fundamental role in pathogen recognition and activation of innate immunity to microbial agents. Sharing structural and functional similarities, highly conserved TLRs recognize pathogen-associated molecular patterns expressed on infectious agents and mediate cytokine production necessary for effective immunity. TLR1 binds to the TLR2 extracellular domain and cooperates with TLR2. TLR1 appears to bind MyD88 via their TIR domains, and to TRAF6, leading to NF-Kappa-B activation, cytokine secretion, and inflammatory response. (NCI) ( NCI )]
UMLS (NCI) C0971363TLR1
TLR1 protein
Toll/Interleukin-1 Receptor-Like
Toll-Like Receptor 1
TLR1 protein
Toll/Interleukin-1 Receptor-Like
Toll-Like Receptor 1
- Amino Acid, Peptide, or Protein
- Receptor
Buy website
Medical Clinic. Optician. Pharmacy. Physician. Travel Agency. Hotel reservation. Child Care. Education. Teachers. Lessons. Tests and Exams. Certification. Shopping Center. Store. Real Estate.Affordable prices from $100.
  |
home
