Ticarcillin Disodium

[The disodium salt of ticarcillin, a broad-spectrum, semi-synthetic Penicillin antibiotic with bactericidal activity. Similar to carbenicillin in action, ticarcillin acylates C-terminal domain of penicillin-sensitive transpeptidase, resulting in opening the lactam ring of the antibiotic. This inactivation prevents the formation of the cross-linkage of peptidoglycan strands, thereby inhibiting the third and last stage of bacterial cell wall synthesis. As a result, cell wall integrity is compromised and cell lysis may follow. This agent usually is administered with a beta-lactamase inhibitor such as clavulanic acid. ( NCI )]

UMLS (NCI) C0546880

Organic Chemical
Antibiotic

Relation/PAR: TICARCILLIN

Relation/CHD: TICARCILLIN DISODIUM 3
TICARCILLIN DISODIUM 3 GM/100ML
TICARCILLIN DISODIUM 3 GM/VIL
TICARCILLIN DISODIUM 30 MG/ML
TICARCILLIN DISODIUM 40 MG/ML
TICARCILLIN DISODIUM 20 GM/VIL
TICARCILLIN DISODIUM 30 GM/VIL
TICARCILLIN DISODIUM 1 GM/VIL

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