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UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
W W0 W1 W4 W6 WA WB WD WE WF WH WI WN WO WR WT WU WV WY
WEA WEB WEC WED WEE WEG WEI WEL WEN WER WES WET

Werner Syndrome Protein

[The WS gene encodes WRN, a 1,432-amino acid polypeptide. WRN is a member of the RecQ family of DNA helicases that unwind duplex DNA. It can also digest DNA exonucleolytically with 3'-5' polarity. WRN may facilitate pol d-mediated DNA replication and/or DNA repair and disruption of WRN-DNA polymerase delta interaction in WS cells may contribute to the S-phase defects and/or the unusual sensitivity to a limited number of DNA damaging agents. (Proc Natl Acad Sci U S A 2000 Apr 25;97(9):4603-8) ( NCI )]
UMLS (NCI) C0388246
 
Amino Acid, Peptide, or Protein
Enzyme

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