- 1. ABC test
- [ ] (UMLS (CSP) C0597877) =Laboratory Procedure ;
| - 10. ABCB6
- [ATP-Binding Cassette, Sub-Family B, Member 6, encoded by the ABCB6 gene, is a membrane-associated protein of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. It could be involved in the transport of heme from the mitochondria to the cytosol. This gene is a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function. (From LocusLink, Swiss_Prot and NCI) ( NCI )] (UMLS (NCI) C1334777) ATP-Binding Cassette, Sub-Family B, Member 6;
Mitochondrial ABC Protein 3 =Amino Acid, Peptide, or Protein; Biologically Active Substance |
- 2. ABC Transport Protein
- [ABC transporters consist of two integral membrane proteins (permeases) each having six transmembrane segments, two peripheral membrane proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. The ATP-binding protein component is the most conserved, the membrane protein component is somewhat less conserved, and the substrate-binding protein component is most divergent. ( NCI )] (UMLS (NCI) C0242738) =Amino Acid, Peptide, or Protein; Biologically Active Substance
| - 11. ABCC1
- [The MRP1 Protein constitutes a multidrug resistance-associated plasma membrane drug-efflux pump, detectable in lung, testis, and peripheral blood mononuclear cells. This transporter protein is similar to ABC superfamily of transport systems and is over expressed in a multidrug-resistant SCLC cell line. (from OMIM 158343 and NCI) ( NCI )] (UMLS (NCI) C0906368) ATP-Binding Cassette, Sub-Family C, Member 1;
MRP1 Protein;
Multiple Drug Resistance-Associated Protein;
=Amino Acid, Peptide, or Protein; Biologically Active Substance ;
◊ [This gene plays a role in multi-drug resistance and organic anion transport. ( NCI )] (UMLS (NCI) C0919458) ABCC1 Gene; ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 Gene; Gene or Genome ; |
- 3. ABC Transporter Binding
- [ABC Transporter Binding involves temporary non-covalent interaction of a molecule through intermolecular physical forces of attraction with a protein complex that, after conformational change, moves a bound substrate across a cell membrane against a concentration gradient resulting directly from the expenditure of energy. ABC Transporter complexes consist of two conserved six-transmembrane proteins (permeases), two conserved ATP-hydrolyzing peripheral membrane proteins, and a periplasmic substrate-binding protein. ( NCI )] (UMLS (NCI) C1510679) =Molecular Function ;
| - 12. ABCcodes
- [Five character alphabetic codes fit into current claims processing software or onto standard paper claim forms. ABC Codes give business parity to licensed CAM and nurse providers who file claims to insurance companies. . ( HL7V3.0 )] (UMLS (HL7) C1553861) =Intellectual Product =CodeSystem;
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- 4. ABC Transporter, MHC 1
- [Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP), encoded by the TAP1 gene, is a member of the superfamily of ATP-binding cassette (ABC) transporters. Being a member of the MDR/TAP subfamily and a subunit of the heterodimeric TAP1/TAP2 complex (TAP), this protein is involved in antigen processing. TAP transports peptides from the cytoplasm to the endoplasmic reticulum for assembly of MHC class I molecules. Loss of TAP function occurs more often in metastatic than in primary tumors. Loss of TAP1 expression may enhance tumor growth by enabling them to escape T-cell recognition during the effector phase of an antitumor immune response in immunized mice. However, it does not change the immunogenicity of tumor cells in the priming phase. Mutations in the TAP1 gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. (From LocusLink 6890, PMID 12019164 and NCI) ( NCI )] (UMLS (NCI) C0140599) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
| - 13. Abcess
- (UMLS (HL7) C1550609) =Body Substance =SpecimenEntityType;
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- 5. ABC Transporter, MHC 2
- [Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP), encoded by the TAP2 gene, is a member of the superfamily of ATP-binding cassette (ABC) transporters. Being a member of the MDR/TAP subfamily and a subunit of the heterodimeric TAP1/TAP2 complex (TAP), this protein is involved in antigen processing. TAP transports peptides from the cytoplasm to the endoplasmic reticulum for assembly of MHC class I molecules. Loss of TAP function occurs more often in metastatic than in primary tumors. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Alternative splicing of this gene produces two products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules. (From LocusLink 6891, PMID 11773612 and NCI) ( NCI )] (UMLS (NCI) C0165949) =Amino Acid, Peptide, or Protein; Immunologic Factor
| - 14. ABCG2
- [Human ATP binding cassette transporter-G2 protein (2436 aa, ~270 kDa) is encoded by the human ABCG2 gene. This integral membrane protein plays a role in transport and is associated with drug resistance in tumor cell lines. ( NCI )] (UMLS (NCI) C0761993) ATP Binding Cassette Transporter G2;
ATP-Binding Cassette, Sub-Family G, Member 2;
BCRP1 Protein;
Breast Cancer Resistance Protein 1;
Mitoxantrone Resistance Protein;
Placenta Specific MDR Protein;
Placenta-Specific ATP-Binding Cassette Transporter =Amino Acid, Peptide, or Protein; Biologically Active Substance |
- 6. ABC-DLBCL
- [A biologic subset of diffuse large B-cell lymphomas with a unique molecular signature or expression profile. It represents approximately 30% of diffuse large B-cell lymphomas, and is characterized by the expression of CD44, PKCbeta1, Cyclin D2, BCL-2, and IRF4/MUM1 genes. Morphologically, these lymphomas are either centroblastic or immunoblastic (ratio 2:1). Patients with this type of diffuse large B-cell lymphoma are reported to have a less favorable outcome compared to those with a germinal center B-cell expression profile, with a 5-year survival rate of 35% and a median survival of 2 years. — 2004 ( NCI )] (UMLS (NCI) C1333296) Activated B-Cell-Like Diffuse Large B-Cell Lymphoma;
Diffuse Large B-Cell Lymphoma with an Activated B-Cell Expression Profile;
=Neoplastic Process ;
| - 15. ABCG2
- [This gene plays a role in xenobiotic transport and multi-drug resistance. ( NCI )] (UMLS (NCI) C1332002) ABCG2 Gene;
ATP-Binding Cassette, Sub-Family G (WHITE), Member 2 Gene;
=Gene or Genome ;
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- 7. ABCB1
- [gene product of the multidrug resistance gene mdr-1, believed to be a membrane spanning transporter that can pump a wide variety of cytotoxic agents out of the cell. ( CSP )] (UMLS (NCI) C0242643) =Amino Acid, Peptide, or Protein; Biologically Active Substance =membrane transport protein;
| - 16. ABCM
- (UMLS (NCI) C0279181) =Therapeutic or Preventive Procedure
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- 8. ABCB1
- [This gene plays a role in multi-drug resistance and is involved in blood-brain barrier transport. ( NCI )] (UMLS (NCI) C0376622) =Gene or Genome
| - 17. ABCX
- (UMLS (NCI) C0279465) =Therapeutic or Preventive Procedure
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- 9. ABCB6
- [This gene is involved in multi-drug resistance, antigen presentation and is postulated to play a role in mitochondrial function. ( NCI )] (UMLS (NCI) C1332001) ABCB6 Gene;
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 6 Gene;
=Gene or Genome ;
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