- 1. BMP
- [protein family consisting of 9 structurally related proteins belonging to the transforming growth factor beta superfamily. ( CSP )] (UMLS (CSP) C0053932) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
=TGF;
| - 12. BMP5
- [This gene plays a role in the regulation of mesenchymal differentiation. It is involved in cartilage and bone formation. ( NCI )] (UMLS (NCI) C1332426) BMP5 Gene;
Bone Morphogenetic Protein 5 Gene;
=Gene or Genome |
- 2. BMP10
- [This gene plays a role in cartilage and bone formation. It is involved in cellular growth and proliferation. ( NCI )] (UMLS (NCI) C1332422) BMP10 Gene;
Bone Morphogenetic Protein 10 Gene;
=Gene or Genome ◊ [Encoded by human BMP10 Gene (TGF-beta Family), 424-aa 48-kD homodimeric secreted Bone Morphogenetic Protein 10 is a putative growth factor that may signal through receptor serine/threonine kinases involved in trabeculation of the embryonic heart. (NCI) ( NCI )] (UMLS (NCI) C1332588) BMP-10; Bone Morphogenetic Protein 10; Amino Acid, Peptide, or Protein; Biologically Active Substance | - 13. BMP6
- [Bone morphogenetic protein 6, encoded by the BMP6 gene, is a member of the TGF-beta family. It has strong similarity to murine Bmp6, signals through receptor serine/threonine kinases, and is involved in endochondral bone formation. (From LocusLink) ( NCI )] (UMLS (NCI) C0537467) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
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- 3. BMP15
- [Bone Morphogenetic Protein 15 encoded by the BMP15 gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The transforming growth factor-beta superfamily includes large families of growth and differentiation factors. It is thought that this protein may be involved in oocyte maturation and follicular development as a homodimer or by forming heterodimers with a related protein, Gdf9. Bone morphogenetic protein 15 signals through receptor serine/threonine kinases. (From LocusLink) ( NCI )] (UMLS (NCI) C0905649) BMP-15;
Bone Morphogenetic Protein 15;
GDF-9B;
Growth/Differentiation Factor 9B =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
| - 14. BMP6
- [This gene plays a role in enchondral bone formation. It is also involved in promoting the growth of dendrites. ( NCI )] (UMLS (NCI) C1332427) BMP6 Gene;
Bone Morphogenetic Protein 6 Gene;
=Gene or Genome |
- 4. BMP15
- [This gene is involved in signal transduction during oogenesis. ( NCI )] (UMLS (NCI) C1332423) BMP15 Gene;
Bone Morphogenetic Protein 15 Gene;
=Gene or Genome | - 15. BMP7
- [Bone Morphogenetic Protein 7 (BMP7), encoded by the BMP7 gene, is a member of the TGF-beta family. BMP7 signals through receptor serine/threonine kinases and has very strong similarity to murine Bmp7. BMP7 plays a role in calcium regulation and bone homeostasis. It induces cartilage and bone formation and may be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. BMP7 is expressed in the kidney and bladder and lower levels are seen in the brain. At all anatomical sites disrupted by Holt-Oram syndrome mutations, BMP7 is expressed in all structures that are altered in Holt-Oram Syndrome patients, including the heart, proximal and distal forelimb, clavicle, and scapula, as well as other unaffected tissues. (NCI) ( NCI )] (UMLS (NCI) C0083867) =Amino Acid, Peptide, or Protein; Biologically Active Substance
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- 5. BMP2
- [Bone Morphogenetic Protein 2, encoded by the BMP2 gene, is a protein that belongs to the transforming growth factor-beta (TGFB) superfamily. By signaling through receptor serine/threonine kinases, Bone morphogenic protein 2 induces bone formation. BMP2 is a candidate gene for the autosomal dominant disease of fibrodysplasia (myositis) ossificans progressiva. (From LocusLink) ( NCI )] (UMLS (NCI) C0527443) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
| - 16. BMP7
- [This gene is involved in calcium regulation and bone homeostasis. It also plays a role in the control of cellular development and differentiation. ( NCI )] (UMLS (NCI) C1332428) BMP7 Gene;
Bone Morphogenetic Protein 7 Gene;
=Gene or Genome |
- 6. BMP2
- [This gene plays a role in bone formation via regulation of osteoblast differentiation. It is also involved in cell cycle regulation. ( NCI )] (UMLS (NCI) C1332424) BMP2 Gene;
Bone Morphogenetic Protein 2 Gene;
=Gene or Genome | - 17. BMP8
- [Bone morphogenetic protein 8 (BMP8), encoded by the BMP8 gene, is a member of the TGF-beta family of growth factors and signals through receptor serine/threonine kinases. BMP8 plays a role in calcium regulation and bone homeostasis. It induces cartilage and bone formation and may be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. (NCI) ( NCI )] (UMLS (NCI) C0527442) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
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- 7. BMP3
- [Bone Morphogenetic Protein 3 (Osteogenic), encoded by the BMP3 gene that belongs to the transforming growth factor-beta (TGFB) superfamily. Bone morphogenic protein 3 induces bone formation by signaling through receptor serine/threonine kinases. It is expressed in lung, ovary and small intestine. The expression signals of BMP3 mRNA in malignant schwannoma are relatively lower than in benign lesions. (From LocusLink, Swiss_Prot and NCI) ( NCI )] (UMLS (NCI) C0069675) =Amino Acid, Peptide, or Protein; Biologically Active Substance
| - 18. BMP8B
- [This gene plays a role in calcium regulation and bone homeostasis. It is involved in cartilage and bone formation. ( NCI )] (UMLS (NCI) C1412806) BMP8B Gene;
Bone Morphogenetic Protein 8b (Osteogenic Protein 2) Gene =Gene or Genome |
- 8. BMP3
- [This gene is involved in bone and cartilage formation. It plays a role in the negative regulation of bone density. ( NCI )] (UMLS (NCI) C1332425) BMP3 Gene;
Bone Morphogenetic Protein 3 Gene;
=Gene or Genome | - 19. BMPR1A
- [The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Germline mutations in BMPR1A cause a subset of juvenile polyposis syndrome and Cowden syndrome. (From LocusLink) ( NCI )] (UMLS (NCI) C0662917) =Amino Acid, Peptide, or Protein; Receptor ;
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- 9. BMP3B
- [This protein is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice suggest that the protein encoded by this protein plays a role in skeletal morphogenesis. (LocusLink) ( NCI )] (UMLS (NCI) C0386581) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
| - 20. BMPR1A
- [This gene plays a role in the bone morphogenetic protein signaling pathway. ( NCI )] (UMLS (NCI) C1332430) BMPR1A Gene;
Bone Morphogenetic Protein Receptor, Type IA Gene;
=Gene or Genome |
- 10. BMP4
- [ ] (UMLS (CSP) C0530979) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
| - 21. BMPR2
- [Encoded by human BMPR2 Gene (BMP Receptor Family), Bone Morphogenetic Protein Receptor Type II is a type II transmembrane serine/threonine kinase receptor for BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. BMP receptors transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling; type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. (NCI) ( NCI )] (UMLS (NCI) C0299048) =Amino Acid, Peptide, or Protein; Enzyme; Receptor
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- 11. BMP5
- [Bone Morphogenetic Protein 5, encoded by the BMP5 gene, is a member of the TGF-beta family of growth factors. Morphogenetic Protein 5 signals through receptor serine/threonine kinases and induces cartilage and bone formation. It is expressed in the lungs and liver. (NCI) ( NCI )] (UMLS (NCI) C0537464) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
| - 22. BMPR2
- [This gene is involved in receptor mediated ligand-induced signal transduction that is critical for endochondral bone formation and embryogenesis. ( NCI )] (UMLS (NCI) C1332431) BMPR2 Gene;
Bone Morphogenetic Protein Receptor, Type II (Serine/Threonine Kinase) Gene;
=Gene or Genome |
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