- 1. 2-CdA/CLB
- (UMLS (NCI) C0281307) =Therapeutic or Preventive Procedure ;
| - 11. CD168 Antigen
- [Encoded by human HMMR Gene and expressed in normal breast tissue, the 724-amino acid 84 kD Hyaluronan-Mediated Motility Receptor is similar to murine Hmmr. A subunit of the HARC complex, the hyaluronan receptor is required for cell motility and may regulate ERK activity. Phosphorylation of several proteins, including pp125-FAK, occurs when Hyaluronan binds HMMR; FAK phosphorylation is necessary for disassembly of focal contacts and motility. HMMR is up regulated in response to wound healing. (from Swiss-Prot, OMIM, and NCI) ( NCI )] (UMLS (NCI) C0388570) =Amino Acid, Peptide, or Protein; Receptor ;
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- 2. 2-CdA/CTX/PRED
- (UMLS (NCI) C0678010) =Therapeutic or Preventive Procedure
| - 12. CD184 Antigen
- [Encoded by human CXCR4 Gene (GPCR1 Family), widely expressed 39.7-kD SDF1/PBSF Receptor CXCR4 is a sulfated 352-amino acid integral membrane leukocyte-activating receptor for CXC chemokine SDF1/PBSF that signals intracellular calcium flux and contains common GPCR features; a 7-transmembrane region and putative glycosylation and phosphorylation sites. Responsible for B-cell lymphopoiesis, myelopoiesis, cardiogenesis, and GI tract vascularization, CXCR4 may be involved in CNS development and can mediate leukocyte and hematopoietic cell migration. It is a primary receptor for some HIV-2 viruses and a CD4 co-receptor for some HIV-1 viruses by promoting env-mediated fusion. (from LocusLink, Swiss-Prot, OMIM, and NCI) ( NCI )] (UMLS (NCI) C0250501) =Amino Acid, Peptide, or Protein; Immunologic Factor; Receptor
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- 3. 2-CdA/IDA
- (UMLS (NCI) C0677832) =Therapeutic or Preventive Procedure ;
| - 13. CD235A
- [Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. In addition to the M or N and S or s antigens, that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta; also, Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are resulted from gene recombinations between GYPA and GYPB. (from RefSeq) ( NCI )] (UMLS (NCI) C0017955) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
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- 4. 2-CdA/VP-16
- (UMLS (NCI) C0392926) =Therapeutic or Preventive Procedure ;
| - 14. CD30 Antigen
- [Expressed in activated T- and B-cells by human TNFRSF8 Gene (TNFR Superfamily) as distinct serine and tyrosine phosphorylated Long (595-aa, 64-kDa precursor type I membrane protein) and Short (cytoplasmic) isoforms, TNF Receptor 8 contains 6 TNFR-Cys repeats. A positive regulator of apoptosis and receptor for TNFSF8/CD30L, TNFRSF8 interacts with the TRAF1, TRAF2, TRAF3, and TRAF5 mediators of signal transduction and regulates gene expression through NF-Kappa-B activation. A Hodgkin's disease associated antigen, TNFRSF8 limits the proliferative potential of autoreactive CD8 effector T cells and protects against autoimmunity. (NCI) ( NCI )] (UMLS (NCI) C0054950) =Amino Acid, Peptide, or Protein; Immunologic Factor; Receptor
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- 5. 2CDA
- [An anticancer drug that belongs to the family of drugs called antimetabolites. ( NCI )] (UMLS (NCI) C0092801) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance =2-Chloroadenosine;
[AN300] ANTINEOPLASTICS, ANTIMETABOLITES;
[AN000] ANTINEOPLASTICS;
Deoxyadenosines;
[IM600] IMMUNE SUPPRESSANTS;
deoxyadenosine =CLADRIBINE 1 MG/ML;
| - 15. CD31 Antigen
- [A cell adhesion molecule present on virtually all monocytes, platelets, and granulocytes, CD31 is highly expressed on endothelial cells and concentrated at the junctions between them. An integral membrane glycoprotein that contains six extracellular Ig-like domains, one transmembrane domain, and a cytoplasmic domain, CD31 is most similar to the CAM subgroup of the Ig superfamily. PECAM1 is implicated in several functions, including transendothelial migration of leukocytes, angiogenesis, and integrin activation. Ig superfamily members mediate cell adhesion, or antigen recognition, T-cell receptors, and MHC molecules. A subgroup contains one or more cytoplasmic ITIM motifs. PECAM1 has six ITIMs and may serve as a negative regulator of platelet-collagen interactions that may limit growth of platelet thrombi on collagen surfaces. (from OMIM 173445 and NCI) ( NCI )] (UMLS (NCI) C0081939) =Amino Acid, Peptide, or Protein; Immunologic Factor ;
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- 6. CD antigen
- [differentiation antigens (markers) of lymphocyte subsets on cell membrane which are defined by monoclonal antibodies. ( CSP )] (UMLS (CSP) C0003322) =Immunologic Factor
| - 16. CD32 Antigen
- [Expressed in monocytes, macrophages, neutrophils, eosinophils, platelets, NK cells, and T- and B-lymphocytes by human FCGR2A Gene, 281-aa (mature) IgG Fc Receptor IIA is a type I cell surface membrane protein with 2 extracellular IgC2 domains and a low affinity receptor for aggregated IgG Fc region. FCGR2A binding to IgG initiates essential effector and regulatory cellular responses against foreign pathogens and soluble antigens that induce phagocytosis of antigen-antibody complexes, removing them from circulation, and modulate B-cell antibody production. An Arg167His polymorphism affects efficiency of IgG2 recognition. (NCI) ( NCI )] (UMLS (NCI) C1448238) Fc-Gamma-RIIA;
CD32;
FCG2;
Fc-Gamma RIIA;
FcGR;
FCGR2;
FCGR2A;
FCGR2A1;
FcRIIA;
IGFR2;
IgG Fc Receptor IIA;
Low Affinity IgG Fc Fragment Receptor IIA;
Low Affinity Immunoglobulin Gamma Fc Region Receptor IIA;
=Amino Acid, Peptide, or Protein; Receptor ;
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- 7. CD114 Antigen
- [Colony Stimulating Factor 3, encoded by the CSF3 gene, is a cytokine that controls the production, differentiation, and function of granulocytes. The active protein is found extracellularly. Three transcript variants encoding three different protein isoforms have been found for this gene. (From LocusLink) ( NCI )] (UMLS (NCI) C0080090) =Amino Acid, Peptide, or Protein; Receptor
| - 17. CD3AP protein
- [ ] (UMLS (CSP) C0287353) =Amino Acid, Peptide, or Protein; Receptor ;
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- 8. CD130 Antigen
- [Widely expressed (not restricted to IL6 responsive cells) by human IL6ST Gene (Type I Cytokine Receptor 2 Family), heterodimeric type I membrane protein (isoform 1) and secreted (isoform 2) Interleukin 6 Signal Transducer contains 5 fibronectin type III domains, an Ig-like C2-type domain, a BOX 1 motif required for JAK interaction/activation, and a WSXWS motif necessary for protein folding, intracellular transport, and cell-surface receptor binding. Part of cytokine receptor complexes, IL6ST is a signal transducer dependent on receptor binding for activation by many cytokines (IL6, CNTF, LIF, IL11, CT1, and OSM) that can utilize gp130 in signal transmission. IL6ST may regulate myocyte apoptosis and have a role in embryonic development. Isoform 2 is an autoantigen in rheumatoid arthritis but it is not specific to RA. (NCI) ( NCI )] (UMLS (NCI) C1366325) gp130 Transducer Chain;
IL6ST;
Interleukin 6 Signal Transducer;
Interleukin Receptor Beta Chain;
Membrane Glycoprotein gp130 =Amino Acid, Peptide, or Protein; Receptor | - 18. CD8 Antigen, Beta Polypeptide 1 (p37) Gene
- [This gene is involved in the mediation of cytotoxic T cells and class I major histocompatibility interactions. ( NCI )] (UMLS (NCI) C1367471) CD8B1;
CD8B1 Gene =Gene or Genome |
- 9. CD142 Antigen
- [coagulation factor important in the formation of extrinsic prothrombin converting principle in the extrinsic pathway of blood coagulation; derived from several sources in the body including brain and lungs. ( CSP )] (UMLS (NCI) C0040048) =Amino Acid, Peptide, or Protein; Immunologic Factor ;
=Blood Coagulation Factor;
| - 19. CDA Level 1 Multipart
- [The HL7 clinical document Architecture, Level 1 MIME package. ( HL7V3.0 )] (UMLS (HL7) C1555003) =Intellectual Product =MultipartMediaType;
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- 10. CD167A Antigen
- [Encoded by human DDR1 Gene (PTK Family, Insulin Receptor Subfamily), 913-amino acid 101 kD (precursor) Epithelial Discoidin Domain Receptor 1, a type I membrane protein homolog of mouse Ptk3, is largely expressed in epithelial cells of kidney, lung, gastrointestinal tract, and brain. DDR1 exhibits extracellular Discoidin I motifs; GLY/PRO-rich domains likely required for ligand or substrate interaction; a F5/8 type C domain; and a novel N-terminal region with homology to a factor VIII domain. The C-terminal catalytic domain has type II receptor tyrosine kinase motifs. Neurotrophin TRKs - TRKA, TRKB, and TRKC - regulate development and survival of specific neuronal lineages. Activated by type I-VI collagens, NTRK4 may be a non-neuronal receptor for a NGF or involved in cell-cell interactions or cell adhesion. (from Swiss-Prot Q08345 and NCI) ( NCI )] (UMLS (NCI) C0294276) =Amino Acid, Peptide, or Protein; Enzyme; Receptor
| - 20. CDA Level One clinical document
- [A clinical document that conforms to Level One of the HL7 Clinical Document Architecture (CDA) ( HL7V3.0 )] (UMLS (HL7) C1554975) =Intellectual Product =clinical document;
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