- 1. c K ras
- [ ] (UMLS (CSP) C0079061) =Gene or Genome
| - 7. CK
- [A quantitative measurement of the amount of creatine kinase present in a sample. ( NCI )] (UMLS (NCI) C0201973) =Laboratory Procedure
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- 2. c kit
- [A protein on the surface of some cells that binds to stem cell factor (a substance that causes certain types of cells to grow). Altered forms of this receptor may be associated with some types of cancer. ( NCI )] (UMLS (CSP) C0072470) =Amino Acid, Peptide, or Protein; Immunologic Factor; Receptor
| - 8. CK19
- [A protein often found as a cell surface marker on tumor cells. ( NCI )] (UMLS (NCI) C0010806) =Amino Acid, Peptide, or Protein; Biologically Active Substance
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- 3. c-K-Ras
- [p21 K-RAS protein is encoded by the K-RAS gene. Two KRAS isoforms are produced by alternative splicing. RAS proteins are involved in transmembrane signal transduction as monomeric GTP-binding proteins, with intrinsic GTPase activity, that alternate between an inactive GDP-bound form and an active GTP-bound form. RAS proteins are activated by a guanine nucleotide-exchange factor and inactivated by a GTPase-activating protein. Mitogen-stimulated RAS enhances MYC accumulation by stabilizing MYC protein. This stabilization is dependent on the RAS/RAF/MAPK pathway, which appears to inhibit the proteasome-dependent degradation of MYC. Mutations of specific amino acids activate c-RAS to transform cells and are implicated in a variety of human tumors. KRAS is involved in malignancy much more often than is HRAS. (from OMIM 190070, SWISS-PROT P01116, P01118, and NCI) ( NCI )] (UMLS (NCI) C0079973) =Amino Acid, Peptide, or Protein; Enzyme
| - 9. CKB
- [Encoded by human CKB Gene (ATP:Guanido Phosphotransferase Family), 381-aa 43-kDa cytoplasmic homodimer or heterodimer Creatine Kinase is a transferase involved in energy homeostasis that primarily catalyzes reversible formation of ATP and creatine from phosphocreatine. Important in muscle contraction, the reaction stores ATP energy as phosphocreatine. Three cytoplasmic isoenzymes have been identified in human tissues: MM from skeletal muscle, MB from myocardial tissue and BB from nervous tissue as well as a mitochondrial isoenzyme. Macro-creatine kinase refers to creatine kinase complexed with other serum proteins. (NCI) ( NCI )] (UMLS (NCI) C0010287) =Amino Acid, Peptide, or Protein; Enzyme =other phosphotransferase;
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- 4. C-Kit Ligand
- [expressed during embryogenesis and provides key signal in multiple aspects of mast cell differentiation and function; hematopoietic growth factor and ligand of c-kit receptor CD117. ( CSP )] (UMLS (NCI) C0143630) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
=Cytokine;
hematopoietic growth factor | - 10. CKB
- [This gene plays a role in cellular energy homeostasis. ( NCI )] (UMLS (NCI) C1332763) CKB Gene;
Creatine Kinase, Brain Gene =Gene or Genome |
- 5. C21KG
- [Encoded by human RAP1A Gene (RAS GTPase Family), 184-aa 21-kDa (precursor) membrane-bound RAS-Related Protein RAP1A is activated by guanine nucleotide-exchange factors EPAC and EPAC2, in a cAMP-dependent manner, and by GFR. Interacting with RAS GAPs and RAF in a competitive manner, RAP1A counteracts RAS mitogenic function. (NCI) ( NCI )] (UMLS (NCI) C0967718) G-22K;
GTP-Binding Protein SMG-P21A;
KREV-1 Protein;
RAP1A;
RAP1A Member of RAS Oncogene Family;
RAS-Related Protein RAP1A;
SMGP21 =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
| - 11. CKD602
- (UMLS (NCI) C0762739) =Organic Chemical; Pharmacologic Substance
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- 6. CK
- [A group of islands in the South Pacific Ocean, about one-half of the way from Hawaii to New Zealand. (NCI) ( NCI )] (UMLS (NCI) C0009956) =Geographic Area
| - 12. CKMB
- [A measurement of the heterozygous MB-type creatine kinase in a biological specimen. ( NCI )] (UMLS (NCI) C0523584) =Laboratory Procedure
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