- 1. CP-358,774
- (UMLS (NCI) C0910101) =Organic Chemical; Pharmacologic Substance
| - 3. CP-724,714
- [An orally bioavailable quinazoline with potential antineoplastic activity. CP-724,714 selectively binds to the intracellular domain of HER2, reversibly inhibiting its tyrosine kinase activity and resulting in suppression of tumor cell growth. HER2, a member of the epidermal growth factor receptor (EGFR) family, is overexpressed in many adenocarcinomas, particularly breast cancers. (NCI04) ( NCI )] (UMLS (NCI) C1327906) =Organic Chemical; Pharmacologic Substance
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