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UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
D D D- D0 D1 D2 D5 D7 D8 D9 DA DB DC DD DE DF DG DH DI DJ DK DL DM DN DO DP DR DS DT DU DV DW DX DY
DHA DHE DHF DHI DHO DHP
selected terms: 3
 
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1. DHFR
[Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. It is a drug target. Variation in gene expression or sequence may alter the efficacy of chemotherapy. (from LocusLink and NCI) ( NCI )] (UMLS (NCI) C0039667) =Amino Acid, Peptide, or Protein; Enzyme ;
=amine oxidoreductase;
Genes, Reporter
3. DHFR Inhibitor
[Substances that inhibit Dihydrofolate Reductase interfering with the conversion of Dihydrofolate to Tetrahydrofolate, causing inhibition of nucleotide biosynthesis and protein synthesis. ( NCI )] (UMLS (NCI) C1373048) Dihydrofolate Reductase Inhibitor;
Dihydrofolate Reductase Inhibitors;
=Pharmacologic Substance ;
=antifolate;
2. DHFR
[This gene is involved in biosynthesis, nucleotide metabolism and the immune response. ( NCI )] (UMLS (NCI) C1333216) DHFR Gene;
Dihydrofolate Reductase Gene =Gene or Genome ;

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