- 1. ERB Oncogene Family
- [Retrovirus-associated DNA sequences originally isolated from, or related to, the avian erythroblastosis virus (AEV). The c-erbA proto-oncogene encodes the thyroid hormone receptors, and the c-erbB family codes for the epidermal growth factor receptor (erbB-1, EGFR) and related receptors (erbB-2, erbB-3). ( NCI )] (UMLS (NCI) C0919435) =Gene or Genome ;
| - 6. ERBB2
- [Herstatin is a secreted alternative ERBB2 product, of the extracellular domain, that binds to p185ERBB2, disrupts ERBB2 dimers, reduces p185 phosphorylation, and inhibits growth. ( NCI )] (UMLS (NCI) C1336034) Herstatin;
sErbB-2;
Soluble ErbB-2 =Amino Acid, Peptide, or Protein; Receptor |
- 2. Erb-38
- [A toxic substance linked to an antibody that attaches to tumor cells and kills them. ( NCI )] (UMLS (NCI) C0677808) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor
| - 7. ERBB2 Interacting Protein Gene
- [This gene is involved in signal transduction and protein localization and function. ( NCI )] (UMLS (NCI) C1333352) ERBB2IP;
ERBB2IP Gene;
=Gene or Genome; ;
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- 3. ERBA Beta Protein
- [Thyroid Hormone Receptor Beta comprises at least two dimeric thyroid hormone receptor transcription factors expressed in liver and some other tissues. The receptor encoded by gene ERBA2 (THR1, THRB) on chromosome 3 is one form of the thyroid hormone receptor beta. Separated from ERBA2 by 50-120 kb, the ERBA1 locus encodes a second beta form of the receptor. (from OMIM 190160 and NCI) ( NCI )] (UMLS (NCI) C0242469) =Amino Acid, Peptide, or Protein; Receptor
| - 8. ERBB3
- [This gene is involved in signal transduction pathways that result in cellular proliferation or differentiation. The gene has also been associated with numerous cancers. ( NCI )] (UMLS (NCI) C0812265) ERBB3 Gene;
V-ERB-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) Gene =Gene or Genome |
- 4. erbB Receptor Family
- [A family of cellular proteins encoded by the c-erbB genes, including epidermal growth factor receptor. They are normally expressed in a variety of tissues of epithelial, mesenchymal, and neuronal origin. They are overexpressed in a significant portion of adenocarcinomas found at various sites, especially in the breast. Gene amplification appears to be the predominant method leading to overexpression. ( NCI )] (UMLS (NCI) C1333436) ErbB Receptor Family Protein =Amino Acid, Peptide, or Protein; Enzyme; Receptor
| - 9. ERBB4
- [This gene is involved in neuronal development and plays a role in receptor tyrosine kinase signal transduction that regulates cellular proliferation and differentiation. ( NCI )] (UMLS (NCI) C0812267) ERBB4 Gene;
V-ERB-A Erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) Gene =Gene or Genome |
- 5. ERBB2
- [This gene plays a role in cellular proliferation and is involved in the oncogenic process through amplification and/or overexpression in several cancers. ( NCI )] (UMLS (NCI) C0242957) =Gene or Genome ;
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