- 1. erg
- [1 dyn.cm ( HL7V3.0 )] (UMLS (HL7) C1551083) =Quantitative Concept =UnitOfMeasureAtomInsens;
UnitOfMeasureAtomSens | - 10. Ergomar
- (UMLS (NCI) C0700758) =Organic Chemical; Pharmacologic Substance
|
- 2. ERG
- [A member of the ETS family of transcription factors closely related to FLI1, Transforming Protein ERG shows homology to two domains of the ETS oncogene. ERG1 and ERG2 are products of alternative splicing and polyadenylation, as well as translation initiation. ERG2 is a nuclear phosphoprotein that binds to purine-rich sequences. Like other ETS proteins, ERG2 is a sequence-specific DNA-binding protein and expressed at higher levels in early myeloid cells than in mature lymphoid cells. ERG2 acts as a regulator of genes required for maintenance and/or differentiation of early hematopoietic cells. (from OMIM 165080 and NCI) ( NCI )] (UMLS (NCI) C0295291) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
| - 11. ergonomics
- [science relating to humans and their work, embodying the anatomical, physiological, psychological, and mechanical aspects of efficiency, productivity, workers' health, and the like. ( CSP )] (UMLS (CSP) C0086246) =Occupation or Discipline ;
=bioengineering;
=computer human interaction |
- 3. ERG-Associated Protein with Set Domain
- [Widely expressed (high in testis) by human SETDB1 Gene (Suvar3-9 Family) as 2 alternative isoforms, 1291-aa 143-kDa nuclear Histone H3-K9 Methyltransferase 4, excluded from nucleoli and condensed chromatin, methylates histone H3 Lys-9 in epigenetic transcriptional repression that recruits HP1 proteins to methylated histones. SETDB1 contains an MBD domain, a pre-SET, a SET, and a post-SET domain, and 2 Tudor domains; pre-SET, SET and post-SET are required for methyltransferase activity. Isoform 2 lacks all methyltransferase domains. The conserved SET domain is implicated in transcriptional modulation of active or repressed chromatin through remodeling. Targeted to histone by TRIM28/TIF1B, SETDB1 contributes to euchromatic gene silencing by KRAB zinc-finger proteins and may interact with ERG. (NCI) ( NCI )] (UMLS (NCI) C1120304) ESET;
H3-K9-HMTase 4;
Histone H3-K9 Methyltransferase 4;
Histone-Lysine N-Methyltransferase H3 Lysine-9 Specific 4;
SET Domain Bifurcated 1;
SETDB1 =Amino Acid, Peptide, or Protein; Enzyme ;
| - 12. Ergonomics
- (UMLS (HL7) C1552289) =Professional or Occupational Group =Occupational Therapist;
◊ (UMLS (HL7) C1552299) Professional or Occupational Group Physical Therapist; |
- 4. Ergamisole
- (UMLS (NCI) C0733385) =Organic Chemical; Pharmacologic Substance
| - 13. ergosterol
- [sterol occurring mainly in yeast and forming ergocalciferol (vitamin D2) upon irradiation by ultraviolet light or electron bombardment. ( CSP )] (UMLS (CSP) C0014705) =Steroid; Pharmacologic Substance; Vitamin =cholestane compound;
|
- 5. Ergastoplasm
- [Membrane organelle of eukaryotes that forms sheets and tubules. Contains the receptor for the signal receptor particle and binds ribosomes engaged in translating mRNA for secreted proteins and the majority of transmembrane proteins. Also a site of membrane lipid synthesis. The membrane is very similar to the nuclear outer membrane. The lumen contains a number of proteins that possess the C terminal signal KDEL. ( NCI )] (UMLS (NCI) C0230779) =Cell Component
| - 14. ergot
- [ ] (UMLS (CSP) C0086247) =Fungus ;
|
- 6. ERGB Transcription Factor
- [Similar to other ETS transcription factors, ERGB Transcription Factor (FLI1) regulates expression of the TGF-beta type II receptor gene. FLI1 contains one PNT domain, can form homodimers or heterodimers with ETV6/TEL1, and recognizes the sequence C[CA]GGAAGT. Two isoforms may be produced by alternative splicing. A form of Ewing's sarcoma is characterized by the chromosomal translocation t(11;22)(q24;q12), which involves FLI1 and EWS. (NCI) ( NCI )] (UMLS (NCI) C0919503) FLI1;
FLI1 Protein;
FLI1 Transcription Factor;
Friend Leukemia Virus Integration 1 Protein;
Friend Leukemia Virus Integration 1 Transcription Factor =Amino Acid, Peptide, or Protein; Biologically Active Substance | - 15. ergot alkaloid
- [Alkaloids originally isolated from the ergot fungus Claviceps purpurea (Hypocreaceae). They include compounds that are structurally related to ergoline (ERGOLINES) and ergotamine (ERGOTAMINES). Many of the ergot alkaloids act as alpha-adrenergic antagonists. ( MSH )] (UMLS (CSP) C0014707) =Organic Chemical; Pharmacologic Substance; Biologically Active Substance =alkaloid;
=Dihydroergotoxine;
ergoline;
|
- 7. Ergenyl
- (UMLS (NCI) C0700659) =Lipid; Pharmacologic Substance
| - 16. Ergotaman-3',6',18-trione, 12'-hydroxy-2'-methyl-5'-(phenylmethyl)-,(5'alpha)-,(2R,3R)-2,3-dihydroxybutanedioate(2:1)(salt)
- [The tartrate salt form of ergotamine, an ergot alkaloid and adrenergic alpha agonist with vasoconstrictor activity. Ergotamine tartrate selectively binds to alpha-adrenergic receptors thereby stimulating vascular smooth muscle and causing vasoconstriction in both arteries and veins. Ergotamine tartrate also blocks serotonin 5-HT1D receptors, thereby also causing vasoconstriction in cerebral blood vessels. Constriction of cerebral blood vessels caused by this agent may reduce the blood flow and pressure in cerebral arteries and may relieve the pain of vascular headaches. ( NCI )] (UMLS (NCI) C0086248) =Organic Chemical; Pharmacologic Substance =ERGOTAMINE;
=ERGOTAMINE TARTRATE 1 MG;
ERGOTAMINE TARTRATE 0.36 MG/ACTUAT;
ERGOTAMINE TARTRATE 2 MG;
ERGOTAMINE TARTRATE 0.6 MG;
ERGOTAMINE TARTRATE 0.3 MG |
- 8. ergoline
- [series of structurally-related alkaloids that contain the ergoline backbone structure. ( CSP )] (UMLS (CSP) C0014699) =Organic Chemical =alkaloid;
Ergot Alkaloids;
Heterocyclic Compounds with 4 or More Rings;
=2-Bromo-alpha-ergocryptine;
LSD;
PERGOLIDE;
2-Bromo-alpha-ergocryptine;
ERGONOVINE;
ERGOTAMINE;
methylsergide;
PERGOLIDE;
1-((6-Allylergolin-8beta-yl)carbonyl)-1-(3-(dimethylamino)propyl)-3-ethylurea | - 17. ERGOTAMINE
- [A naturally occurring ergot alkaloid with vasoconstrictor and analgesic property. Ergotamine selectively binds and activates serotonin (5-HT) 1D receptors located on intracranial blood vessels, including those on arterio-venous anastomoses, thereby resulting in vasoconstriction and reducing the blood flow in cerebral arteries that may lead to relieve of vascular headaches. This agent also selectively binds to alpha-adrenergic receptors, thereby stimulating vascular smooth muscle and causing vasoconstriction in both arteries and veins, which also contributes to the relief of headaches. Furthermore, the activation of 5-HT1D receptors on sensory nerve endings of the trigeminal system results in the inhibition of pro-inflammatory neuropeptide release. ( NCI )] (UMLS (NCI) C0014710) =Organic Chemical; Pharmacologic Substance ;
=ergoline;
[CN105] ANTIMIGRAINE AGENTS =Ergotaman-3',6',18-trione, 12'-hydroxy-2'-methyl-5'-(phenylmethyl)-,(5'alpha)-,(2R,3R)-2,3-dihydroxybutanedioate(2:1)(salt);
Ergotamine Derivatives;
Ergotaman-3',6',18-trione, 12'-hydroxy-2'-methyl-5'-(phenylmethyl)-,(5'alpha)-,(2R,3R)-2,3-dihydroxybutanedioate(2:1)(salt) |
- 9. Ergoline-8-carboxamide, 9,10-didehydro-N-((1S)-1-(hydroxymethyl)propyl)-6-methyl-,(8beta)-,(2Z)-2-butenedioate(1:1)(salt)
- [The maleate salt of methylergonovine, a semi-synthetic ergot alkaloid with vasoconstrictive and uterotonic effects. Methylergonovine stimulates serotoninergic and dopaminergic receptors as well as inhibits the release of endothelial-derived relaxation factor. This results in arterial vasoconstriction and increased uterine smooth muscle contractions. ( NCI )] (UMLS (NCI) C0289432) =Organic Chemical; Pharmacologic Substance ;
=Methylergonovine;
=METHYLERGONOVINE MALEATE 0.2 MG;
METHYLERGONOVINE MALEATE 0.2 MG/ML | |
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