- 1. ETS Family Gene
- [The Ets family of transcription factors includes nuclear phosphoproteins that are involved in cell proliferation, differentiation and oncogenic transformation. The family is defined by a conserved DNA-binding domain (the ETS-DBD), which forms a highly conserved, winged, helix-turn-helix structural motif. As targets of the Ras-MAPK signaling pathway, Ets proteins function as critical nuclear integrators of ubiquitous signaling cascades. To direct signals to specific target genes, ETS proteins interact with other transcription factors that determine the binding specificity of ETS proteins to RAS-response elements in target genes. ( NCI )] (UMLS (NCI) C0812200) ETS Family Proto-Oncogenes;
=Gene or Genome ;
| - 7. ETS Variant Gene 4 (E1A Enhancer Binding Protein, E1AF) Gene
- [This gene plays a regulatory role in transcription and in matrix metalloproteinase activity. ( NCI )] (UMLS (NCI) C1333362) ETV4;
ETV4 Gene;
=Gene or Genome; ;
|
- 2. ETS Family Protein
- [ETS family proteins exhibit sequence homology with the transcription factor ETS protooncogene. ( NCI )] (UMLS (NCI) C0919488) ETS Protein;
ETS-Domain Transcription Factor;
=Amino Acid, Peptide, or Protein; Biologically Active Substance | - 8. ETS Variant Gene 6 (TEL Oncogene) Gene
- [This gene plays a regulatory role in transcription and in matrix metalloproteinase activity. ( NCI )] (UMLS (NCI) C0796520) ETV6;
ETV6 Gene;
=Gene or Genome |
- 3. ETS Related Protein PE-1
- [ETV3 Protein, a member of the ETS proto-oncogene family of transcription factors, contains the conserved ETS domain that mediates sequence-specific DNA binding. (from OMIM 164873 and NCI) ( NCI )] (UMLS (NCI) C0256645) =Amino Acid, Peptide, or Protein; Biologically Active Substance
| - 9. Ets Variant Protein 1
- [DNA-binding protein of the ETS family; contains a DNA binding domain (LocusLink) ( NCI )] (UMLS (NCI) C1333478) ETV1 =Amino Acid, Peptide, or Protein; Biologically Active Substance
|
- 4. ETS Translocation Variant 6
- [TEL protein is a member of the ETS family of transcription factors. It has an HLH motif and an ETS DNA-binding domain. Translocations of the gene produce chimeric proteins in many leukemias of myeloid or lymphoid origins. Leukemogenic translocations often fuse the TEL HLH domain with the tyrosine kinase domain of other genes, such as PDGFRB, NTRK3, and ABL2 or with other transcription factors, such as AML1 and ARNT. (from OMIM 600618 and NCI) ( NCI )] (UMLS (NCI) C0254343) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
| - 10. ETS1
- [This gene is involved in transcriptional activation and may play a role in the suppression of tumorigenicity. ( NCI )] (UMLS (NCI) C0812201) ETS1 Gene;
v-ETS Erythroblastosis Virus E26 Oncogene Homolog 1 (Avian) Gene;
=Gene or Genome |
- 5. ETS Variant Gene 1 Gene
- [This gene is involved in transcriptional activation and spinal cord development. ( NCI )] (UMLS (NCI) C1333361) ETV1;
ETV1 Gene;
=Gene or Genome; ;
| - 11. ETS2
- [This gene is involved in transcriptional activation and skeletal development. ( NCI )] (UMLS (NCI) C0812202) ETS2 Gene;
v-ETS Erythroblastosis Virus E26 Oncogene Homolog 2 (Avian) Gene;
=Gene or Genome |
- 6. ETS Variant Gene 3 Gene
- [This gene plays a regulatory role in transcription, terminal differentiation and cell cycle arrest. ( NCI )] (UMLS (NCI) C0812270) ETV3;
ETV3 Gene;
=Gene or Genome | |
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