- 1. 10H-Benzo(4,5)cyclohepta(1,2-b)thiophen-10-one, 4,9-dihydro-4-(1-methyl-4-piperidinylidene)-,(E)-2-butenedioate(1:1)
- [The fumarate salt of ketotifen, a cycloheptathiophene derivative with anti-allergic activity. Ketotifen selectively blocks histamine (H1) receptors and prevents the typical symptoms caused by histamine release. This agent also interferes with the release of inflammatory mediators from mast cells involved in hypersensitivity reactions, thereby decreasing chemotaxis and activation of eosinophils. ( NCI )] (UMLS (NCI) C0043443) =Organic Chemical; Pharmacologic Substance ;
=KETOTIFEN;
=KETOTIFEN FUMARATE 0.025 % | - 12. 2H-1,4-Benzodiazepine-2-thione, 7-chloro-5-(2-fluorophenyl)-1,3-dihydro-1-(2,2,2-trifluoroethyl)-
- [A synthetic benzodiazepine derivative with anxiolytic, sedative and hypnotic properties. Quazepam and its major metabolite 2-oxoquazepam potentiate gamma-aminobutyric acid (GABA) activity by binding to the benzodiazepine-1 recognition site (BZ-1) within the GABA-A receptor, located in the limbic, neocortical and mesencephalic reticular system. This increases the frequency of GABA-activated chloride channel opening events, allowing the flow of chloride ions into the neuron leading to membrane hyperpolarization and decreased neuronal excitability. ( NCI )] (UMLS (NCI) C0072828) =Organic Chemical; Pharmacologic Substance =[CN302] BENZODIAZEPINE DERIVATIVE, SEDATIVES/HYPNOTICS;
Unclassified Ingredients =QUAZEPAM 15 MG;
QUAZEPAM 7.5 MG;
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- 2. 1H-1,4-Benzodiazepine-3-carboxylic acid, 7-chloro-2,3-dihydro-2-oxo-5-phenyl-, Monopotassium Salt, compound with Potassium Hydroxide
- [A benzodiazepine with anxiolytic, sedative, hypnotic, and anticonvulsant properties. Clorazepate dipotassium exerts its effect by de-activating the nervous system through potentiation of the inhibitory effect of gamma-aminobutyric acid (GABA) on the GABA-A receptors by binding to a site that is distinct from the GABA binding site. Its inhibitory effect is caused by an increase in GABA-mediated chloride channel opening events, leading to hyperpolarization and synaptic inhibition. ( NCI )] (UMLS (NCI) C0009033) =Organic Chemical; Pharmacologic Substance ;
=benzodiazepine;
CLORAZEPATE PREPARATION =CLORAZEPATE DIPOTASSIUM 15 MG;
CLORAZEPATE DIPOTASSIUM 22.5 MG;
CLORAZEPATE DIPOTASSIUM 7.5 MG;
CLORAZEPATE DIPOTASSIUM 11.25 MG;
CLORAZEPATE DIPOTASSIUM 3.75 MG;
| - 13. 2H-1-Benzopyran-2-one
- [oxygen containing heterocyclic compound, obtainable naturally from several plants, or produced synthetically from an amino acid of phenylalanine; it is used for the preparation of drugs especially anticoagulants such as bishydroxycoumarin (dicoumarol) and warfarin (coumadin); coumarin glycosides such as dicoumarol and warfarin, are widely used as rodenticides. ( CSP )] (UMLS (NCI) C0010206) =Organic Chemical; Pharmacologic Substance =pyrone;
=furocoumarin;
1-(4'-Hydroxy-3'-coumarinyl)-1-phenyl-3-butanone;
|
- 3. 1H-Benz(de)isoquinolin-1-one, 2-(3S)-1-azabicyclo(2.2.2)oct-3-yl-2,3,3a,4,5,6-hexahydro-, Monohydrochloride,(3aS)-
- [The hydrochloride salt form of palonosetron, a carbazole derivative and a selective serotonin receptor antagonist with antiemetic properties. Palonosetron competitively blocks the action of serotonin at 5-HT3 receptors located on vagal afferents in the chemoreceptor trigger zone (CTZ), resulting in suppression of chemotherapy-induced nausea and vomiting. ( NCI )] (UMLS (NCI) C1310734) PALONOSETRON HCL UNIDENTIFIED;
PALONOSETRON HCL UNIDENTIFIED;
PALONOSETRON HYDROCHLORIDE;
=Organic Chemical; Pharmacologic Substance ;
| - 14. 2H-Benzimidazol-2-one, 1-(1-(4,4-bis(4-fluorophenyl)butyl)-4-piperidinyl)-1,3-dihydro-
- [diphenylbutylpiperidine that is used as an antipsychotic agent and as an alternative to haloperidol for the suppression of vocal and motor tics in patients with Tourette syndrome. ( CSP )] (UMLS (NCI) C0031935) =Organic Chemical; Pharmacologic Substance =benzimidazole;
[CN700] ANTIPSYCHOTICS;
[CN900] CNS MEDICATIONS, OTHER;
=PIMOZIDE 2 MG;
PIMOZIDE 1 MG;
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- 4. 1H-benz(de)isoquinoline-1,3(2H)-dione, 5-amino-2-(2-(dimethylamino)ethyl)
- (UMLS (NCI) C0051733) =Organic Chemical; Pharmacologic Substance
| - 15. 3H-1,4-Benzodiazepin-2-amine, 7-chloro-N-methyl-5-phenyl, 4-oxide
- [anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties; also used in the symptomatic treatment of alcohol withdrawal. ( CSP )] (UMLS (NCI) C0008188) =Organic Chemical; Pharmacologic Substance ;
=benzodiazepine;
tranquilizer;
[CN302] BENZODIAZEPINE DERIVATIVE, SEDATIVES/HYPNOTICS;
=CHLORDIAZEPOXIDE HYDROCHLORIDE;
CHLORDIAZEPOXIDE 10 MG;
CHLORDIAZEPOXIDE 5 MG;
|
- 5. 1H-benzimidazol-2-ylcarbamic Acid Methyl Ester
- [An anticancer drug that belongs to the family of drugs called antifungal agents. ( NCI )] (UMLS (NCI) C0065839) =Organic Chemical; Pharmacologic Substance; Hazardous or Poisonous Substance
| - 16. 4,4'-(3H-2,1-Benzoxathiol-3-ylidene)bis(2-bromo-3-methyl-6-(1-met-hylethyl)phenol) S,S-dioxide
- [A dye used as an indicator in determining pH. Bromthymol blue is a weak acid. It can be in acid or base form, depending on the pH of the solution. This reagent is yellow in acidic solutions, blue in basic solutions and green in neutral solution. ( NCI )] (UMLS (NCI) C0006251) =Organic Chemical; Indicator, Reagent, or Diagnostic Aid
|
- 6. 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 3,4-Dihydro-3-(phenylmethyl)-6-(trifluoromethyl)-, 1,1-Dioxide
- [A thiazide diuretic. Bendroflumethiazide directly inhibits sodium and chloride reabsorption on the luminal membrane of the early segment of the distal convoluted tubule in the kidney. This drug increases water, sodium, chloride, potassium and bicarbonate excretion and decreases calcium and uric acid secretion. Bendroflumethiazide is commonly used to treat hypertension, edema, and congestive heart failure. ( NCI )] (UMLS (NCI) C0004975) =Organic Chemical; Pharmacologic Substance
| - 17. 4H-1-benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)-8-methoxy-
- (UMLS (NCI) C0072562) =Organic Chemical
|
- 7. 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 3,4-dihydro-6-(trifluoromethyl)-, 1,1-Dioxide
- [A thiazide diuretic with antihypertensive activity. Hydroflumethiazide directly inhibits sodium and chloride reabsorption on the luminal membrane of the early segment of the distal convoluted tubule in the kidney. This results in an increase in water, sodium, chloride, potassium and bicarbonate excretion and a decrease in calcium and uric acid secretion. (NCI05) ( NCI )] (UMLS (NCI) C0020273) =Organic Chemical; Pharmacologic Substance ;
=benzothiadiazine;
[CV701] THIAZIDES/RELATED DIURETICS =HYDROFLUMETHIAZIDE 50 MG | - 18. 4H-1-benzopyran-8-acetic Acid, 4-Oxo-2-phenyl
- [A synthetic flavonoid with vascular targeting properties. Flavone acetic acid exhibits an antiproliferative effect on endothelial cells as a result of a superoxide-dependent mechanism, which induces changes in permeability of the vasculature of the tumor. This agent may stimulate tumor necrosis and promote shunting of blood flow to viable regions of the tumor, increasing their oxygenation and rendering them more susceptible to the antitumor effects of hyperthermia and ionizing radiation. (NCI04) ( NCI )] (UMLS (NCI) C0060441) =Organic Chemical; Pharmacologic Substance
|
- 8. 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-2-methyl-3-(((2,2,2-trifluoroethyl)thio)methyl)-, 1,1-Dioxide
- [A sulfonamide derivative and a synthetic thiazide with diuretic, antihypertensive and anti-urolithic properties. By blocking the Na/Cl transporter, polythiazide inhibits reabsorption of sodium and chloride in the proximal and distal convoluted tubule of the kidney, resulting in increased excretion of water and electrolytes (sodium, potassium, chloride, magnesium, and bicarbonate) and subsequent reversal of hypertension. In addition, this agent exerts its anti-urolithic effect by decreasing calcium and uric acid excretion. ( NCI )] (UMLS (NCI) C0032613) =Organic Chemical; Pharmacologic Substance ;
=benzothiadiazine;
[CV701] THIAZIDES/RELATED DIURETICS =POLYTHIAZIDE 0.5 MG;
POLYTHIAZIDE 1 MG;
POLYTHIAZIDE 2 MG;
POLYTHIAZIDE 4 MG;
| - 19. 5H-(1)Benzopyrano(2,3-b)pyridine-3-carboxylic Acid, 2-Amino-7-(1-methylethyl)-5-oxo-
- [An anti-aphthous ulcer drug. Amlexanox inhibits the synthesis and release of inflammatory mediators, including leukotrienes and histamine, from mast cells, neutrophils, and mononuclear cells. Amlexanox also acts as a leukotriene D4 antagonist and a phosphodiesterase inhibitor. Amlexanox decreases the time ulcers take to heal as well as the pain associated with the ulcers. ( NCI )] (UMLS (NCI) C0103049) =Organic Chemical; Pharmacologic Substance =aminopyridine;
[OR900] DENTAL AND ORAL AGENTS, TOPICAL OTHER =AMLEXANOX 5 %;
|
- 9. 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(chloromethyl)-3,4-dihydro-2-methyl-, 1,1-Dioxide
- [A thiazide diuretic with antihypertensive activity. Methyclothiazide directly inhibits sodium and chloride reabsorption on the luminal membrane of the early segment of the distal convoluted tubule in the kidney. This results in an increase in water, sodium, chloride, potassium and bicarbonate excretion and a decrease in calcium and uric acid secretion. ( NCI )] (UMLS (NCI) C0025696) =Organic Chemical; Pharmacologic Substance ;
=benzothiadiazine;
[CV701] THIAZIDES/RELATED DIURETICS =NIVEA SKIN OIL;
METHYCLOTHIAZIDE 2.5 MG;
METHYCLOTHIAZIDE 5 MG | - 20. 5H-Benzo(5,6)cyclohepta(1,2-b)pyridine, 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-
- [A long-acting piperidine derivate with selective H1 antihistaminergic and non-sedating properties. Desloratadine diminishes the typical histaminergic effects on H1-receptors in bronchial smooth muscle, capillaries and gastrointestinal smooth muscle, including vasodilation, bronchoconstriction, increased vascular permeability, pain, itching and spasmodic contractions of gastrointestinal smooth muscle. Desloratadine is used to provide symptomatic relieve of allergic symptoms. ( NCI )] (UMLS (NCI) C0908935) Desloratadine;
DESLORATADINE PREPARATION;
=Organic Chemical; Pharmacologic Substance ;
=[AH900] ANTIHISTAMINES, OTHER;
Unclassified Ingredients =DESLORATADINE 5 MG;
|
- 10. 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(dichloromethyl)-3,4-dihydro-, 1,1-Dioxide
- [A thiazide diuretic with antihypertensive activity. Trichlormethiazide directly inhibits sodium and chloride reabsorption on the luminal membrane of the early segment in the distal convoluted tubule in the kidney. This leads to an increase in water, sodium, chloride, bicarbonate, and potassium secretion and a decrease in calcium and uric acid secretion. ( NCI )] (UMLS (NCI) C0040899) =Organic Chemical; Pharmacologic Substance =[CV701] THIAZIDES/RELATED DIURETICS;
6-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide =TRICHLORMETHIAZIDE 4 MG | - 21. 7H-benzo(e)pyrido(4,3-b)indol-3-ol, 11-((3-(dimethylamino)propyl)amino)-8-methyl
- [An anticancer drug that belongs to the family of drugs called topoisomerase inhibitors. ( NCI )] (UMLS (NCI) C0217476) =Organic Chemical; Pharmacologic Substance ;
|
- 11. 2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-3-hydroxy-5-phenyl-
- [benzodiazepine used in the treatment of anxiety, alcohol withdrawal, and insomnia. ( CSP )] (UMLS (NCI) C0029997) =Organic Chemical; Pharmacologic Substance ;
=benzodiazepine;
Benzodiazepinones;
tranquilizer;
[CN302] BENZODIAZEPINE DERIVATIVE, SEDATIVES/HYPNOTICS =OXAZEPAM 10 MG;
OXAZEPAM 15 MG;
OXAZEPAM 30 MG;
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