- 1. L-Glutamic Acid, N-(4-(2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo(2,3-d)pyrimidin-5-yl)ethyl)benzoyl)
- [A synthetic pyrimidine-based antifolate. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS), which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. ( NCI )] (UMLS (NCI) C0210657) =Organic Chemical; Pharmacologic Substance ;
| - 4. LGD1057
- (UMLS (NCI) C0918021) =Organic Chemical; Pharmacologic Substance ;
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- 2. LG BOWEL DX PROCED NEC
- [ ] (UMLS (ICD9CM) C0176789) =Diagnostic Procedure
| - 5. LGD1069
- (UMLS (NCI) C0300770) =Organic Chemical; Pharmacologic Substance
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- 3. LG BOWEL STOMA REVIS NEC
- [ ] (UMLS (ICD9CM) C0176816) =Therapeutic or Preventive Procedure
| - 6. LGL (large granular lymphocyte) leukemia
- [A spectrum of disorders characterized by clonal expansions of the peripheral blood LYMPHOCYTE populations known as large granular lymphocytes which contain abundant cytoplasm and azurophilic granules. Subtypes develop from either CD3-negative NATURAL KILLER CELLS or CD3-positive T-CELLS. The clinical course of both subtypes can vary from spontaneous regression to progressive, malignant disease. ( MSH )] (UMLS (CSP) C1522378) =Neoplastic Process; ;
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