- 1. 1,8-Naphthyridine-3-carboxylic Acid, 1-ethyl-1,4-dihydro-7-methyl-4-oxo-
- [A synthetic quinolone and antibacterial agent with urinary tract antiseptic activity. Nalidixic acid concentrates in the renal tubules and bladder and exerts its local antibacterial actions by interference of DNA gyrase activity, thereby inhibiting DNA synthesis during bacterial replication in a dose-dependent manner. Nalidixic acid is active against most gram-negative organisms that cause urinary tract infections. ( NCI )] (UMLS (NCI) C0027353) =Organic Chemical; Pharmacologic Substance =Naphthyridines;
[AM900] ANTI-INFECTIVES, OTHER =Nalidixate 250 MG;
Nalidixate 500 MG;
NALIDIXIC ACID 1 GM;
NALIDIXIC ACID 250 MG/5ML;
| - 11. NAPHAZOLINE
- [An imidazole derivative and a direct-acting sympathomimetic amine with vasoconstrictive activity. Upon ocular administration, naphazoline exerts its effect by acting on alpha-adrenergic receptors in the arterioles of the conjunctiva to produce vasoconstriction, resulting in decreased conjunctival congestion and diminished itching, irritation and redness. ( NCI )] (UMLS (NCI) C0027373) =Organic Chemical; Pharmacologic Substance ;
=imidazole;
[OP800] DECONGESTANTS, TOPICAL OPHTHALMIC =1H-Imidazole, 4,5-dihydro-2-(1-naphthalenylmethyl)-, Monohydrochloride |
- 2. 1-Naphthacenecarboxylic acid, 4-[[O-2,6-dideoxy-.alpha.-L-lyxo-hexopyranosyl-(1.fwdarw.4)-O-2, 6-dideoxy-.alpha.-L-lyxo-hexopyranosyl-(1.fwdarw.4)-2,3, 6-trideoxy-3-(dimethylamino)-.alpha.-L-lyxo-hexopyranosyl]oxy]-2-e thyl-1,2,3,4,6,11-hexahydro-2,5,7,10
- [An antineoplastic oligosaccharide anthracycline antineoplastic antibiotic isolated from the bacterium Actinosporangium bohemicum. Marcellomycin intercalates into DNA and induces DNA crosslinks, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent also induces differentiation in HL-60 promyelocytic leukemia cells by interfering with glycoprotein synthesis. (NCI04) ( NCI )] (UMLS (NCI) C0065718) =Organic Chemical; Antibiotic
| - 12. naphtha
- [ ] (UMLS (CSP) C0068407) =Organic Chemical; Hazardous or Poisonous Substance ;
|
- 3. 1-Naphthalenemethanamine, a-methyl-N-(3-(3-(trifluoromethyl)phenyl)propyl)-,(aR)-, Hydrochloride
- [An oral calcimimetic. Cinacalcet hydrochloride increases the sensitivity of the calcium-sensing receptors on the chief cells in the parathyroid gland to extracellular calcium, thereby reducing parathyroid hormone secretion. A reduction in parathyroid hormone levels inhibits osteoclast activity, favourably impacts bone-specific alkaline phosphatase, bone turnover, and bone fibrosis, and leads to normalization of serum calcium and phosphate levels. Cinacalcet hydrochloride is a treatment option for primary and secondary hyperparathyroidism and parathyroid carcinoma. ( NCI )] (UMLS (NCI) C1260199) CINACALCET HCL UNIDENTIFIED;
CINACALCET HCL UNIDENTIFIED;
CINACALCET HYDROCHLORIDE;
=Organic Chemical; Pharmacologic Substance ;
| - 13. naphthalene
- [two-ring crystalline aromatic hydrocarbons isolated from coal tar; used as intermediates in chemical synthesis, as insect repellents, fungicides, lubricants, and preservatives. ( CSP )] (UMLS (CSP) C0027378) =Organic Chemical =carbopolycyclic compound;
PAH =(2S)-2-Methylbutanoic Acid, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester;
6-Methoxy-alpha-methyl-2-naphthaleneacetic Acid;
Mayapple Extract;
1-Naphthylamine;
(2S)-2-Methylbutanoic Acid, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester;
Naphthaleneacetic Acids;
Naphthalenesulfonates;
naphthol;
naphthoquinone;
Tetrahydronaphthalenes;
Carbamothioic Acid, methyl(3-methylphenyl)-, O-2-naphthalenyl Ester;
(E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalene Methanamine;
[1S-[1alpha(betaS*,deltaS*),2alpha,6alpha,8beta(R*),8aalpha]]-1,2,6,7,8,8a-Hexahydro-beta,!d,6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-1-naphthaleneheptanoic Acid;
butenafine;
6-(3-(1-Adamantyl)-4-methoxyphenyl)-2-naphthoic acid |
- 4. 2-Naphthacenecarboxamide, 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-, Monohydrochloride,(4S-(4alpha,4aalpha,5alpha,5aalpha,12aalpha))-
- [The hydrochloride salt form of methacycline, a tetracycline antibiotic with broad-spectrum antibacterial and antiprotozoal activity. Methacycline hydrochloride is bacteriostatic and inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, thereby preventing the addition of amino acids to the growing peptide chain. This tetracycline is active against a wide range of gram-positive and gram-negative bacteria. ( NCI )] (UMLS (NCI) C0770655) Methacycline Hydrochloride;
METHACYCLINE HYDROCHLORIDE PREPARATION;
Optimycin;
Rindex =Organic Chemical; Antibiotic =METHACYCLINE;
=METHACYCLINE HYDROCHLORIDE 300 MG;
METHACYCLINE HYDROCHLORIDE 150 MG | - 14. Naphthalene
- [A white, volatile, solid polycyclic hydrocarbon with a strong mothball odor. Naphthalene is obtained from either coal tar or petroleum distillation and is primarily used to manufacture phthalic anhydride, but is also used in moth repellents. Exposure to naphthalene is associated with hemolytic anemia, damage to the liver and neurological system, cataracts and retinal hemorrhage. Naphthalene is reasonably anticipated to be a human carcinogen and may be associated with an increased risk of developing laryngeal and colorectal cancer. (NCI05) ( NCI )] (UMLS (NCI) C0027375) =Organic Chemical
|
- 5. 2-Naphthacenecarboxamide, 7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, Monohydrochloride(4S-(4alpha,4aalpha,5aalpha,6beta,12aalpha))-
- [A tetracycline with broad-spectrum antibacterial and antiprotozoal activity. Chlortetracycline hydrochloride is bacteriostatic and inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, thereby preventing the addition of amino acids to the growing peptide chain. This tetracycline is active against a wide range of gram-positive and gram-negative organisms, spirochetes, rickettsial species, certain protozoa and Mycoplasma and Chlamydia organisms. ( NCI )] (UMLS (NCI) C0085855) =Organic Chemical; Antibiotic =chlortetracycline;
| - 15. naphthol
- [Naphthalene derivatives carrying one or more hydroxyl (-OH) groups at any ring position. They are often used in dyes and pigments, as antioxidants for rubber, fats, and oils, as insecticides, in pharmaceuticals, and in numerous other applications. ( MSH )] (UMLS (CSP) C0027387) =Organic Chemical =naphthalene;
=[AM250] TETRACYCLINES;
|
- 6. 2-Naphthoic Acid, 4,4'-methylenebis(3-hydroxy-, ester with 2-(2-(4-(p-chloro-alpha-phenylbenzyl)-1-piperazinyl)-ethoxy)ethanol
- [The pamoate salt form of hydroxyzine, a synthetic piperazine histamine H1-receptor antagonist with anti-allergic, antispasmodic, sedative, anti-emetic and anti-anxiety properties. Hydroxyzine pamoate blocks the H1 histamine receptor and prevents the symptoms that are caused by histamine activity on capillaries, bronchial smooth muscle, and gastrointestinal smooth muscle, including vasodilatation, increased capillary permeability, bronchoconstriction, and spasmodic contraction of gastrointestinal smooth muscle. In addition, hydroxyzine pamoate crosses the blood-brain barrier and acts on the histamine H1-receptors in the central nervous system. (NCI05) ( NCI )] (UMLS (NCI) C0700539) =Organic Chemical; Pharmacologic Substance =HYDROXYZINE;
=HYDROXYZINE PAMOATE 100 MG;
HYDROXYZINE PAMOATE 50 MG;
HYDROXYZINE PAMOATE 25 MG/5ML;
HYDROXYZINE PAMOATE 25 MG;
| - 16. naphthoquinone
- [naphthalene rings which contain two ketone moieties in any position. ( CSP )] (UMLS (CSP) C0027388) =Organic Chemical =naphthalene;
Benzoquinone Compound =[VT700] VITAMIN K;
ATOVAQUONE |
- 7. 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-.alpha.-L-lyxo-hexopyranosyl)oxy]-7,8, 9,10-tetrahydro-6,8,11-trihydroxy-8-(1-hydroxyethyl)-1-methoxy-, (8S-cis)-, hydrochloride
- (UMLS (NCI) C0969848) Daunomycinol HCl;
Duborimycin Hydrochloride;
Duborimycine, Hydrochloride;
=Organic Chemical; Pharmacologic Substance ;
| - 17. naphthylamine
- [nitrogen substituted aromatic hydrocarbon existing as two different isomers, both carcinogenic and used in dyes. ( CSP )] (UMLS (CSP) C0260030) =Organic Chemical ;
=cyclic amine;
=1-((1-Methylethyl)amino)-3-(1-naphthalenyloxy)-2-propanol |
- 8. 5,12-Naphthacenedione, 7, 8, 9, 10-tetrahydro-6, 8, 11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-10-[[2, 3, 6-trideoxy-3-(4-morpholinyl)-.alpha.-L-lyxo-hexopyranosyl] oxy]-, hydrochloride, (8S-cis)-
- [A semisynthetic derivative of the anthracycline antineoplastic antibiotic doxorubicin. As an antineoplastic agent, morpholinodoxorubicin is more potent than doxorubicin. Similar to doxorubicin, morpholinodoxorubicin intercalates into DNA and causes single- and double-strand breaks in DNA via inhibition of topoisomerase I and II. Unlike doxorubicin, this agent is metabolized in vivo to a DNA-alkylating derivative that forms DNA interstrand cross-links, thereby potentiating its doxorubicin-like cytotoxicity. (NCI04) ( NCI )] (UMLS (NCI) C0173377) =Organic Chemical; Pharmacologic Substance
| - 18. naphthyridine
- [ ] (UMLS (CSP) C0178756) =Organic Chemical ;
|
- 9. 5,12-Naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-.alpha.-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, (8S-cis)-, hydrochloride
- [The hydrochloride salt of an anthracycline antineoplastic antibiotic with therapeutic effects similar to those of doxorubicin. Daunorubicin exhibits cytotoxic activity through topoisomerase-mediated interaction with DNA, thereby inhibiting DNA replication and repair and RNA and protein synthesis. ( NCI )] (UMLS (NCI) C0282123) =Organic Chemical; Pharmacologic Substance ;
=(8S-cis)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione;
=DAUNORUBICIN HYDROCHLORIDE 20 MG | - 19. Naphuride
- (UMLS (NCI) C0242512) =Organic Chemical; Pharmacologic Substance
|
- 10. NAP2
- [Encoded by human PPBP Gene (Alpha Chemokine CXC Family), secreted 128-aa 14-kDa (precursor) Pro-Platelet Basic Protein is a platelet-derived growth factor that is processed to PBP and CTAP-III. Proteolytic removal of PPBP residues 1-9 produces active peptide CTAP-III/LA-PF4, which stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan, as well as formation and secretion of plasminogen activator. Upon platelet activation, PBP is proteolytically converted to beta thromboglobulin, a homotetramer released when platelets aggregate; CTAP-III is proteolytically converted to NAP2, a potent chemoattractant and activator of neutrophils. (NCI) ( NCI )] (UMLS (NCI) C0132309) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
| - 20. Naprosyn
- (UMLS (NCI) C0700017) =Organic Chemical; Pharmacologic Substance ;
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