- 1. (+)-2-(2-((p-Chloro-alpha-methyl-alpha-phenylbenzyl)oxy)ethyl)-1-methyl Pyrrolidine Fumarate
- [A synthetic ethanolamine with anticholinergic, sedative, and histamine H1 antagonistic properties. Clemastine fumarate blocks the H1 histamine receptor and prevents the symptoms that are caused by histamine activity on capillaries, bronchial and gastrointestinal smooth muscles, including vasodilation, increased capillary permeability, bronchoconstriction, and spasmodic contraction of gastrointestinal smooth muscles. This drug also prevents histamine-induced pain and itching of mucous membranes. ( NCI )] (UMLS (NCI) C0546858) =Organic Chemical; Pharmacologic Substance =CLEMASTINE;
=CLEMASTINE FUMARATE 0.67 MG/5ML;
CLEMASTINE FUMARATE 1.34 MG;
CLEMASTINE FUMARATE 2.68 MG;
| - 26. PC5
- (UMLS (HL7) C1549861) =Intellectual Product =Message structure;
|
- 2. (+)-2-(p-Chloro-alpha-(2-(dimethylamino)ethyl)benzyl)pyridine Maleate(1:1)
- [The maleate salt form of dexchlorpheniramine, an alkylamine, and first-generation histamine antagonist with anti-allergic activity. Dexchlorpheniramine maleate competitively blocks H1 receptors, thereby preventing the actions of histamine on bronchial smooth muscle, capillaries and gastrointestinal (GI) smooth muscle. This prevents histamine-induced bronchoconstriction, vasodilation, increased capillary permeability, and GI smooth muscle spasms. ( NCI )] (UMLS (NCI) C0137440) =Organic Chemical; Pharmacologic Substance ;
=DEXCHLORPHENIRAMINE;
=DEXCHLORPHENIRAMINE MALEATE 2 MG/5ML;
DEXCHLORPHENIRAMINE MALEATE 2 MG;
DEXCHLORPHENIRAMINE MALEATE 4 MG;
DEXCHLORPHENIRAMINE MALEATE 6 MG;
| - 27. PC6, PC7, PC8
- (UMLS (HL7) C1549850) =Intellectual Product =Message structure;
|
- 3. 1-(p-Chlorobenzhydryl)-4-(2-(2-hydroxyethoxy)ethyl)diethylenediamine Hydrochloride
- [The hydrochloride salt form of hydroxyzine, a piperazine histamine H1-receptor antagonist with anti-allergic, antispasmodic, sedative, anti-emetic and anti-anxiety properties. Hydroxyzine hydrochloride blocks the H1 histamine receptor and prevents the symptoms that are caused by histamine activity on capillaries, bronchial smooth muscle, and gastrointestinal smooth muscle, including vasodilatation, increased capillary permeability, bronchoconstriction, and spasmodic contraction of gastrointestinal smooth muscle. In addition, hydroxyzine hydrochloride crosses the blood-brain barrier and acts on the histamine H1-receptors in the central nervous system. (NCI05) ( NCI )] (UMLS (NCI) C0600110) =Organic Chemical; Pharmacologic Substance =HYDROXYZINE;
=HYDROXYZINE HYDROCHLORIDE 100 MG;
HYDROXYZINE HYDROCHLORIDE 25 MG;
HYDROXYZINE HYDROCHLORIDE 50 MG;
HYDROXYZINE HYDROCHLORIDE 50 MG/ML;
HYDROXYZINE HYDROCHLORIDE 10 MG;
HYDROXYZINE HYDROCHLORIDE 25 MG/ML;
HYDROXYZINE HYDROCHLORIDE 10 MG/5ML | - 28. PCA
- (UMLS (HL7) C1549860) =Intellectual Product =Message structure;
|
- 4. 1-(p-Chlorophenyl)-5-isopropylbiguanide Hydrochloride
- [The hydrochloride salt form of proguanil, a synthetic biguanide derivative of pyrimidine and an folate antagonist with antimalarial property. Upon hydrolysis, proguanil is converted to its active cyclic triazine metabolite, cycloguanil, by a cytochrome P450 dependent reaction. Cycloguanil selectively inhibits the bifunctional dihydrofolate reductase-thymidylate synthase (DHFR-TS) of plasmodium parasite, thereby disrupting deoxythymidylate synthesis and ultimately blocking DNA and protein synthesis in the parasite. ( NCI )] (UMLS (NCI) C0546856) =Organic Chemical; Pharmacologic Substance
| - 29. PCA
- [The posterior cerebral artery is formed by the bifurcation of the basilar artery; it divides into three branches. ( NCI )] (UMLS (NCI) C0149576) =Body Part, Organ, or Organ Component
|
- 5. 1-p-carboxy-3,3-dimethylphenyltriazine
- (UMLS (NCI) C0088835) =Organic Chemical; Pharmacologic Substance
| - 30. PCA
- [A statistical method to reduce the dimensionality in a dataset while retaining those characteristics of the dataset that contribute most to its variance. ( NCI )] (UMLS (NCI) C0429865) =Quantitative Concept
|
- 6. 2-(p-Chloro-alpha-(2-(dimethylamino)ethoxy)benzyl)pyridine Bimaleate
- [An ethanolamine class of H1 antihistamines with mild antimuscarinic and sedative properties. Carbinoxamine diminishes the typical histaminergic effects on H1-receptors in bronchial smooth muscle, capillaries, and gastrointestinal smooth muscle, including vasodilation, bronchoconstriction, increased vascular permeability, pain, itching, and spasmodic contractions of gastrointestinal smooth muscle. Carbinoxamine maleate is used to provide symptomatic relieve of allergic symptoms. ( NCI )] (UMLS (NCI) C0304300) =Organic Chemical; Pharmacologic Substance ;
=CARBINOXAMINE;
=CARBINOXAMINE MALEATE 2 MG/ML;
CARBINOXAMINE MALEATE 4 MG;
CARBINOXAMINE MALEATE 4 MG/5ML;
CARBINOXAMINE MALEATE 8 MG;
| - 31. PCA Pump
- [An infusion pump is a device used in a health care facility to pump fluids into a patient in a controlled manner. The device may use a piston pump, a roller pump, or a peristaltic pump and may be powered electrically or mechanically. The device may also operate using a constant force to propel the fluid through a narrow tube which determines the flow rate. The device may include means to detect a fault condition, such as air in, or blockage of, the infusion line and to activate an alarm. ( SPN )] (UMLS (HL7) C0181331) =Medical Device =Administration Device;
|
- 7. 2-[p-(2-Chloro-1,2-diphenylvinyl)phenoxy]triethylamine
- [USP lists as a gonad stimulating principle; is a fertility inhibitor in male and female rats, but is a fertility stimulant in women used to induce multiple births. ( CSP )] (UMLS (NCI) C0009008) =Organic Chemical; Pharmacologic Substance ;
=fertility promoting drug;
[HS400] GONADOTROPINS;
[HS800] PROGESTINS;
stilbene =2-[p-(2-Chloro-1,2-diphenylvinyl)phenoxy]triethylamine Citrate;
| - 32. PCB, PCD
- (UMLS (HL7) C1549857) =Intellectual Product =Message structure;
|
- 8. 2-[p-(2-Chloro-1,2-diphenylvinyl)phenoxy]triethylamine Citrate
- [The citrate salt form of clomiphene, a triphenylethylene nonsteroidal ovulatory stimulant evaluated for antineoplastic activity against breast cancer. Clomiphene has both estrogenic and anti-estrogenic activities that compete with estrogen for binding at estrogen receptor sites in target tissues. This agent causes the release of the pituitary gonadotropins follicle stimulating hormone (FSH) and luteinizing hormone (LH), leading to ovulation. (NCI04) ( NCI )] (UMLS (NCI) C0546859) =Organic Chemical; Pharmacologic Substance =2-[p-(2-Chloro-1,2-diphenylvinyl)phenoxy]triethylamine;
=CLOMIPHENE CITRATE 50 MG;
| - 33. PCC, PCG, PCH, PCJ
- (UMLS (HL7) C1549856) =Intellectual Product =Message structure;
|
- 9. p21(CDKN1A)-Activated Kinase 6 Gene
- [This gene plays a role in development, stress response and reorganization of cell structure. ( NCI )] (UMLS (NCI) C1335189) PAK6;
PAK6 Gene =Gene or Genome | - 34. PCD
- [after lunch (from lat. post cibus diurnus) ( HL7V3.0 )] (UMLS (HL7) C1550744) =Temporal Concept =TimingEvent;
|
- 10. p21/Cdc42/Rac1-Activated Kinase 1 (STE20 Homolog, Yeast) Gene
- [This gene is involved in signal transduction and the regulation of both cell mobility and morphology. ( NCI )] (UMLS (NCI) C1418259) PAK1;
PAK1 Gene =Gene or Genome | - 35. PCF
- (UMLS (HL7) C1549862) =Intellectual Product =Message structure;
|
- 11. p300/CBP-Associated Factor Gene
- [This gene is involved in histone and nucleosome remodeling and transcriptional regulation. ( NCI )] (UMLS (NCI) C1366462) PCAF;
PCAF Gene =Gene or Genome | - 36. PCI-0120
- (UMLS (NCI) C0662850) =Organic Chemical; Pharmacologic Substance; Indicator, Reagent, or Diagnostic Aid
|
- 12. P450 (Cytochrome) Oxidoreductase Gene
- [This gene is involved in the metabolism of estrogen and xenbiotics. ( NCI )] (UMLS (NCI) C1335232) POR;
POR Gene =Gene or Genome | - 37. PCI-0123
- (UMLS (NCI) C0950969) =Organic Chemical; Pharmacologic Substance
|
- 13. p60 (cyclin A)
- [A 33-kDa protein identical to adenovirus E1A-associated protein p60. Cyclin A regulates p33cdk2 and p34cdc2, and is necessary for progression through the S phase of the cell cycle. ( MSH )] (UMLS (CSP) C0079184) =Amino Acid, Peptide, or Protein; Biologically Active Substance
| - 38. PCL
- (UMLS (HL7) C1549859) =Intellectual Product =Message structure;
|
- 14. P62 (cyclin B)
- [A 58-kDa protein that is regulated post-transcriptionally and post-translationally in the cell cycle. ( MSH )] (UMLS (CSP) C0079185) =Amino Acid, Peptide, or Protein; Biologically Active Substance
| - 39. PCM
- [after breakfast (from lat. post cibus matutinus) ( HL7V3.0 )] (UMLS (HL7) C1550743) =Temporal Concept =TimingEvent;
|
- 15. PC
- [after meal (from lat. post cibus) ( HL7V3.0 )] (UMLS (HL7) C1550739) =Temporal Concept =TimingEvent;
| - 40. PCNA
- [This gene plays a role in DNA metabolic processes, such as DNA repair and replication. ( NCI )] (UMLS (NCI) C1366837) PCNA Gene;
Proliferating Cell Nuclear Antigen Gene;
=Gene or Genome ;
|
- 16. PC
- [A country in the Pacific, comprised of islands in the South Pacific Ocean, about midway between Peru and New Zealand. (NCI) ( NCI )] (UMLS (NCI) C0031995) =Geographic Area
| - 41. PCOS
- [clinical symptom complex characterized by presence of multiple cysts on the ovaries, oligomenorrhea or amenorrhea, anovulation and regularly associated with excessive amounts of body hair (hirsuitism), excessive body weight, infertility and insulin resistance. ( CSP )] (UMLS (CSP) C0032460) =Disease or Syndrome ;
=Endocrine Disease;
Cyst of Ovary;
syndrome;
|
- 17. PC-12
- [cell line established from a rat pheochromocytoma; has many properties in common with primary sympathetic neurons and chromaffin cell cultures; used primarily as a neuron model. ( CSP )] (UMLS (NCI) C0085262) =Cell ;
=cell line;
neoplastic cell | - 42. PCP
- [An insecticide and herbicide that has also been used as a wood preservative. Pentachlorphenol is a widespread environmental pollutant. Both chronic and acute pentachlorophenol poisoning are medical concerns. The range of its biological actions is still being actively explored, but it is clearly a potent enzyme inhibitor and has been used as such as an experimental tool. ( MSH )] (UMLS (CSP) C0030855) =Organic Chemical; Hazardous or Poisonous Substance ;
|
- 18. PC-501
- (UMLS (NCI) C0878533) =Organic Chemical; Antibiotic
| - 43. PCP
- [this drug is both a legitimate prescription anesthetic and a notoriously abused street drug also known as "angel dust." ( CSP )] (UMLS (NCI) C0031381) =Organic Chemical; Pharmacologic Substance =[CN200] ANESTHETICS;
hallucinogen;
piperidine;
|
- 19. PC-SPES
- [An herbal mixture with potential antineoplastic effects. PC-SPES, an herbal supplement containing extracts from 8 herbs; including Serenoa repens (saw palmetto), Chrysanthemum morifolium, Ganoderma lucidum, Glycyrrhiza glabra, Isatis indigotica, Panax pseudoginseng, Rabdosia rubescens, Scutelleria baicalensis, which may posses antineoplastic and antiproliferative effects, specifically in prostate cancer cells. The exact pharmacology is not fully understood due to the complexity of the herbal mixture and may involve multiple metabolic pathways. Exposure to PC-SPES in vitro, has resulted in a decreased expression of genes encoding cell cycle regulatory proteins as well as an upregulation of genes which modulate apoptosis, in both androgen-dependent and androgen-independent cells. The acronym, PC-SPES, stands for Prostate Cancer; SPES is the Latin word for hope. ( NCI )] (UMLS (NCI) C0756934) =Pharmacologic Substance; Biologically Active Substance
| - 44. PCP receptor
- [3 subtypes identified with the NMDA receptor/Ca++ channel, dopamine reuptake transporter/K+ channel, and sigma/haloperidol/neuroleptic receptor. ( CSP )] (UMLS (CSP) C0070548) =Amino Acid, Peptide, or Protein; Receptor ;
=calcium channel;
drug receptor |
- 20. PC1
- [A CALCIUM-dependent endopeptidase that has specificity for cleavage at ARGININE that is near paired basic residues. It cleaves a variety of prohormones including PRO-OPIOMELANOCORTIN; PRORENIN; proenkephalins; prodynorphin; prosomatostatin; and PROINSULIN. ( MSH )] (UMLS (CSP) C0135615) =Amino Acid, Peptide, or Protein; Enzyme ;
| - 45. PCR
- [method for reproducing specific DNA sequences based on elongation of complementary primers by DNA polymerase; primarily used to increase quantities for analytical detection of, e.g., virus genome. ( CSP )] (UMLS (NCI) C0032520) =Laboratory Procedure; Molecular Biology Research Technique ;
=molecular cloning;
nucleic acid chemical synthesis;
ObservationMethod;
=RDA |
- 21. PC1, PC2, PC3
- (UMLS (HL7) C1549858) =Intellectual Product =Message structure;
| - 46. PCR DNA fingerprinting
- [ ] (UMLS (CSP) C0599160) =Laboratory Procedure; Molecular Biology Research Technique
|
- 22. PC2
- [A serine endopeptidase that has specificity for cleavage at ARGININE. It cleaves a variety of prohormones including PRO-OPIOMELANOCORTIN, proluteinizing-hormone-releasing hormone, proenkephalins, prodynorphin, and PROINSULIN. ( MSH )] (UMLS (CSP) C0083957) =Amino Acid, Peptide, or Protein; Enzyme
| - 47. PCT
- [Compounds consisting of three benzene rings linked to each other in either ortho, meta or para positions and substituted with chlorine atoms. ( MSH )] (UMLS (CSP) C0032452) =Organic Chemical ;
|
- 23. Pc4
- [A synthetic photosensitizer agent containing a large macrocyclic ring chelated with silicon. Silicon phthalocyanine 4 localizes primarily in mitochondrial cytosolic membranes and, after photoexcitation, forms reactive oxygen species that induce apoptosis. ( NCI )] (UMLS (NCI) C1328695) Pc-4 (Silicone phthalocyanine);
Silicon Phthalocyanine 4 =Organic Chemical; Pharmacologic Substance ;
| - 48. PCTAIRE Protein Kinase 1 Gene
- [This gene is involved in cell cycle regulation and signal transduction. ( NCI )] (UMLS (NCI) C1335197) PCTK1;
PCTK1 Gene =Gene or Genome |
- 24. PC4 and SFRS1 Interacting Protein 1 Gene
- [This gene is involved in regulation of transcription. It also plays a role in mediation of pre-mRNA splicing. ( NCI )] (UMLS (NCI) C1335268) PSIP1;
PSIP1 Gene =Gene or Genome | - 49. PCV
- [after dinner (from lat. post cibus vespertinus) ( HL7V3.0 )] (UMLS (HL7) C1550745) =Temporal Concept =TimingEvent;
|
- 25. PC4, PC9, PCE, PCK
- (UMLS (HL7) C1549872) =Intellectual Product =Message structure;
| |
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