[prostaglandin E2 is the most common and most biologically active of the mammalian prostaglandins; it exhibits most biological activities characteristic of prostaglandins including vasodilation, immune modulatory effects, contraction or relaxation of smooth muscle, inhibition of gastric secretion and sodium resorption inhibition; it has been used extensively as an oxytocic agent and displays a protective effect on the intestinal mucosa; prostaglandin E1 has many similar properties and also inhibits platelet aggregation. ( CSP )] (UMLS (CSP) C0033559) =Eicosanoid; Biologically Active Substance =[HS875] PROSTAGLANDINS; =(11alpha,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-en-1-oic Acid; dinoprostone