UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM - Terms starting with ‘C’

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UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM

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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

P P- P0 P1 P2 P3 P4 P5 P6 P7 P8 P9 PA PB PC PD PE PF PG PH PI PK PL PM PN PO PP PQ PR PS PT PU PV PW PX PY

PK1 PKC PKI PKS

selected terms: 3

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1. PKC: [nonEC. ( CSP )] (UMLS (NCI) C0033634) =Amino Acid, Peptide, or Protein; Enzyme ;
=alcohol phosphotransferase;

3. PKCA: [Encoded by human PRKCA Gene (PKC Family), 672-aa 77-kDa Protein Kinase C-alpha is a calcium-activated (likely by the C2 domain), DAG-activated, phospholipid-dependent serine/threonine kinase containing 2 zinc-dependent phorbol-ester/DAG binding domains and a C2 domain that phosphorylates a range of cellular proteins. DAG markedly increases PKC sensitivity to calcium and phospholipids. PKC activation appears to be central in the induction of cellular responses to many ligand-receptor systems and to external stimuli. After GPCR stimulation, and triggered by PKC-dependent serine phosphorylation, RKIP dissociates from RAF1 to associate with and block GRK2 activity. By activating PKC, the receptor signal may be enhanced by removing a RAF1 inhibitor and blocking receptor internalization. A receptor for phorbol ester tumor promoters, PKC may interact with PRKCABP. (NCI) ( NCI )] (UMLS (NCI) C0256371) =Amino Acid, Peptide, or Protein; Enzyme ;

2. PKC412: [A substance that is being studied as a treatment for cancer. It belongs to the family of drugs called protein kinase C (PKC) inhibitors. ( NCI )] (UMLS (NCI) C0915830) PKC-412;
=Organic Chemical; Pharmacologic Substance ;

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