- 1. (-)-(R)-1-(4,4-Bis(3-methyl-2-thienyl)-3-butenyl)nipecotic Acid, Hydrochloride
- [The hydrochloride salt form of tiagabine, a nipecotic acid derivative with anticonvulsant property. Tiagabine hydrochloride inhibits the gamma-aminobutyric acid (GABA) transporter type 1 (GAT1), which is predominantly localized in presynaptic terminals of neurons thereby preventing the reuptake of GABA by the presynaptic endings. Consequently, this increases the level of available GABA within the synaptic cleft, thereby resulting in prolongation of its inhibitory actions. Tiagabine is effective against maximum electroshock seizures and both limbic and generalized tonic-clonic seizures. ( NCI )] (UMLS (NCI) C0772200) 3-Piperidinecarboxylic Acid, 1-(4,4-bis(3-methyl-2-thienyl)-3-buten-yl)-, Hydrochloride,(R)-;
Tiagabine Hydrochloride;
TIAGABINE HYDROCHLORIDE PREPARATION =Organic Chemical; Pharmacologic Substance =TIAGABINE;
=TIAGABINE HYDROCHLORIDE 12 MG;
TIAGABINE HYDROCHLORIDE 16 MG;
TIAGABINE HYDROCHLORIDE 4 MG;
TIAGABINE HYDROCHLORIDE 2 MG | - 10. RBBP9
- [This gene is involved in the regulation of cellular proliferation and differentiation. ( NCI )] (UMLS (NCI) C1419294) RBBP9 Gene;
Retinoblastoma Binding Protein 9 Gene =Gene or Genome |
- 2. 9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)phosphinyl)methoxy)propyl)adenine, Fumarate
- [A pro-drug, a fumaric acid salt of tenofovir and an acyclic nucleoside phosphonate diester analog with antiviral property. In vivo tenofovir disoproxil fumarate is converted into tenofovir by diester hydrolysis in the intestinal lumen and plasma, followed by internalization into cells by endocytosis and subsequent phosphorylation into tenofovir diphosphate. Tenofovir diphosphate competes with the natural substrate dATP for incorporation into viral DNA by reverse transcriptase of human immunodeficiency virus (HIV). The substituted DNA-tenofovir diphosphate molecule prevents further DNA elongation, and consequently impairs viral replication and propagation. This agent prevents HIV from reproducing in uninfected cells only. Tenofovir also exhibits activity against the hepatitis B virus (HBV). ( NCI )] (UMLS (NCI) C1099776) TDF;
Tenofovir DF;
Tenofovir Disoproxil Fumarate;
TENOFOVIR DISOPROXIL FUMARATE PREPARATION;
=Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance =TENOFOVIR;
Unclassified Ingredients =TENOFOVIR DISOPROXIL FUMARATE 300 MG | - 11. RBC agglutination
- [Agglutination, RBC ( HL7V3.0 )] (UMLS (HL7) C1551409) =Laboratory Procedure =ObservationMethod;
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- 3. r-BDNF
- [A recombinant form of neurotrophic growth factor that regulates the development and maintenance of motor neurons expressing trk B receptor tyrosine kinase, with potential use in neurodegenerative disorders. (NCI) ( NCI )] (UMLS (NCI) C0668698) =Amino Acid, Peptide, or Protein; Pharmacologic Substance ;
| - 12. RBE
- [ratio of radiation dosages required to produce identical change based on a formula comparing other types of radiation with that of gamma or roentgen rays. ( CSP )] (UMLS (CSP) C0035023) =Quantitative Concept ;
=radiation dosage;
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- 4. Rb element
- [alkali metal element; atomic symbol Rb, atomic number 37; used as a chemical reagent and in the manufacture of photoelectric cells. ( CSP )] (UMLS (CSP) C0035930) =Element, Ion, or Isotope =alkali metal;
heavy metal =RUBIDIUM (Rb-82) | - 13. RBL2
- [This gene is involved in transcriptional regulation and cellular proliferation. ( NCI )] (UMLS (NCI) C1335602) RBL2 Gene;
Retinoblastoma-Like 2 (p130) Gene;
=Gene or Genome ;
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- 5. Rb gene
- [Tumor suppressor genes located on human chromosome 13 in the region 13q14 and coding for a family of phosphoproteins with molecular weights ranging from 104 kDa to 115 kDa. One copy of the wild-type Rb gene is necessary for normal retinal development. Loss or inactivation of both alleles at this locus results in retinoblastoma. ( MSH )] (UMLS (CSP) C0079424) =Gene or Genome ;
| - 14. RBM5
- [This gene plays a role in the mediation of nucleic acid-binding interactions. ( NCI )] (UMLS (NCI) C1419301) RBM5 Gene;
RNA Binding Motif Protein 5 Gene =Gene or Genome |
- 6. RB1
- [This gene is involved in the regulation of cell differentiation, growth and proliferation. ( NCI )] (UMLS (NCI) C0694889) =Gene or Genome ;
| - 15. RBM6
- [This gene plays a role in RNA recognition processes and has tumor suppressor activity. ( NCI )] (UMLS (NCI) C1335604) RBM6 Gene;
RNA Binding Motif Protein 6 Gene;
=Gene or Genome ;
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- 7. Rb81 isotope
- [ ] (UMLS (CSP) C0303553) =Element, Ion, or Isotope
| - 16. RBX1
- [Widely expressed by human RBX1 Gene (RING-Box Family), conserved cytoplasmic and nuclear 108-aa 12.3-kDa RING Box Protein 1, containing a RING-type zinc finger, mediates protein turnover of cell cycle, signal transduction, and transcription proteins by ubiquitination and proteasomal degradation. A component of various SCF, SCF-like, and CBC multisubunit E3 ubiquitin ligase complexes, RBX1 may recruit E2 enzymes to the complex through its RING-type zinc finger and heterodimerizes with cullins in the third step of ubiquitin conjugation reactions to catalyze ubiquitin polymerization. RBX1 promotes neddylation of CUL1 and probably CUL2. It also probably interacts with CDC34 and may stimulate CDC34 autoubiquitination. (NCI) ( NCI )] (UMLS (NCI) C1313794) Regulator of Cullins 1;
RING Box Protein 1;
RING Finger Protein;
RING Finger Protein 75;
ROC1;
ZYP Protein =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
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- 8. Rb86 isotope
- [ ] (UMLS (CSP) C0303558) =Indicator, Reagent, or Diagnostic Aid; Element, Ion, or Isotope ;
| - 17. RBX1
- [This gene plays a critical role in ubiquitination. ( NCI )] (UMLS (NCI) C1335605) RBX1 Gene;
Ring-Box 1 Gene;
=Gene or Genome ;
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- 9. RBBB
- [An impairment of transmission of the cardiac electrical impulse along the fibers of the right bundle branch. A " complete RBBB pattern" (with QRS duration > 0.11s) does not necessarily reflect the existence of a total conduction block in the right branch. This pattern only indicates that the entire or major parts of both ventricles are activated by the impulse emerging from the left branch. Thus, a significant degree of conduction delay ("high-grade" or "incomplete RBBB) can produce a similar pattern. ( NCI )] (UMLS (NCI) C0085615) =Disease or Syndrome
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