- 1. ryanodine
- [binds to and inhibits the calcium-sensitive calcium channel of muscle sarcoplasmic reticulum and homologous organelles in other cell types, blocking the fast calcium release step in intracellular signal transduction. ( CSP )] (UMLS (CSP) C0035983) =Organic Chemical; Pharmacologic Substance; Biologically Active Substance =alkaloid;
[CV200] CALCIUM CHANNEL BLOCKERS | - 2. ryanodine receptor
- [A tetrameric calcium release channel in the SARCOPLASMIC RETICULUM membrane of smooth muscle cells, acting oppositely to SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES. It is important in skeletal and cardiac excitation-contraction coupling and studied by using RYANODINE. Abnormalities are implicated in ARRHYTHMIAS, CARDIAC and MUSCULAR DISEASES. ( MSH )] (UMLS (CSP) C0054493) =Amino Acid, Peptide, or Protein; Receptor ;
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