- 1. 3T3 cell
- [a ubiquitous tissue culture model for nontransformed animal cells; derived from nonneoplastic immortalized fibroblasts. ( CSP )] (UMLS (CSP) C0085087) =Cell ;
=cell line;
| - 25. T-Cell Receptor Interacting Molecule
- [Expressed in T cells (not B cells or monocytes) of the thymus, spleen, lymph nodes, and peripheral leukocytes by human TRIM Gene, 186-aa 29/30-kD disulfide-linked dimeric type III transmembrane adaptor phosphoprotein T-Cell Receptor Interacting Molecule contains an 8-aa extracellular domain (includes a Cys residue), a 19-aa transmembrane region and an intracellular domain with 4 potential phosphorylation sites likely involved in SH2-mediated interactions with signaling proteins. Associated with CD3E and CD3Z, TRIM modulates the TCR-CD3 complex in T lymphocytes. After T-cell activation, TRIM is tyrosine phosphorylated by Src kinases and associates with PIK3R1. (NCI) ( NCI )] (UMLS (NCI) C0756533) TCRIM;
TCR-Interacting Molecule;
TRIM;
=Amino Acid, Peptide, or Protein; Biologically Active Substance |
- 2. 3TC/d4T/IDV
- (UMLS (NCI) C0393010) =Therapeutic or Preventive Procedure
| - 26. T-Cell Receptor, Alpha-Beta
- [T-cell receptors composed of CD3-associated alpha and beta polypeptide chains and expressed primarily in CD4+ or CD8+ T-cells. Unlike immunoglobulins, the alpha-beta T-cell receptors recognize antigens only when presented in association with major histocompatibility (MHC) molecules. ( MSH )] (UMLS (NCI) C0085247) =Amino Acid, Peptide, or Protein; Immunologic Factor; Receptor
|
- 3. 5'-tct ccc agc gtg cgc cat
- [A drug that may kill cancer cells by blocking the production of a protein that makes cancer cells live longer. ( NCI )] (UMLS (NCI) C0914297) Oblimersen;
olbimersen =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
| - 27. T-Cell Receptor, Gamma-Delta
- [T-cell receptors composed of CD3-associated gamma and delta polypeptide chains and expressed primarily in CD4-/CD8- T-cells. The receptors appear to be preferentially located in epithelial sites and probably play a role in the recognition of bacterial antigens. The T-cell receptor gamma/delta chains are separate and not related to the gamma and delta chains which are subunits of CD3 (see ANTIGENS, CD3). ( MSH )] (UMLS (NCI) C0085246) =Amino Acid, Peptide, or Protein; Immunologic Factor; Receptor
|
- 4. T cadherin
- [ ] (UMLS (CSP) C0390690) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
| - 28. T-Cell Rich/Histiocyte-Rich Large B-Cell Lymphoma
- (UMLS (NCI) C1321547) T-Cell/Histiocyte Rich Lymphoma =Neoplastic Process ;
|
- 5. T Cell
- [lymphocytes responsible for cell-mediated immunity, formed when lymphocytes circulate through the thymus gland and differentiate to thymocytes; when exposed to an antigen, they divide rapidly and produce large numbers of new T cells sensitized to that antigen. ( CSP )] (UMLS (NCI) C0039194) =Cell =lymphocyte;
=helper T lymphocyte;
suppressor T lymphocyte;
CTL;
| - 29. T1c
- (UMLS (NCI) C0475386) =Classification
|
- 6. T Cell Receptor Signaling Pathway
- [The T Cell Receptor plays a key role in the immune system. The specificity of the receptor is governed by the binding site formed from the mature alpha and beta chains or gamma and delta chains in gamma/delta T Cells. It is the ability of this receptor to bind a complex of foreign peptide in the groove of an MHC molecule that leads to T cell activation. Upon activation the T cell can assist in activating other cells or carry out cytolytic attacks depending on the particular T cell type. The CD3 complex and CD4 (Th cells) or CD8 (Tc cells) work to transmit the activation signal to the T cell's transcriptional machinery upon engagement of the receptor. (BioCarta) ( NCI )] (UMLS (NCI) C1325934) =Molecular Function ;
| - 30. T2c
- (UMLS (NCI) C0475389) =Classification
|
- 7. T-Cell Activation
- [T-Cell Activation involves stimulation of T lymphocytes by receptor interaction with mitogens or cell surface-displayed antigens resulting in biosynthesis of lymphokines, cell proliferation, cell differentiation, and maturation to support immune activity. ( NCI )] (UMLS (NCI) C1155065) =Cell Function
| - 31. T3c
- (UMLS (NCI) C0475394) =Classification
|
- 8. T-Cell and NK-Cell Neoplasm
- (UMLS (NCI) C1336554) T-Cell Neoplasm =Neoplastic Process ;
| - 32. T4c
- (UMLS (NCI) C0475397) =Classification ;
|
- 9. T-cell depletion
- [Treatment to destroy T cells, which play an important role in the immune response. Elimination of T cells from a bone marrow graft from a donor may reduce the chance of an immune reaction against the recipient's tissues. ( NCI )] (UMLS (NCI) C0677960) =Therapeutic or Preventive Procedure
| - 33. TC
- [Two island groups in the North Atlantic Ocean, southeast of The Bahamas. (NCI) ( NCI )] (UMLS (NCI) C0041405) =Geographic Area
|
- 10. T-Cell Immunodeficiency
- (UMLS (NCI) C1274233) =Disease or Syndrome
| - 34. Tc 99m
- [One of the radioactive isotopes of technetium, a gamma/beta-emitter with a half life of 6 hours. ( NCI )] (UMLS (NCI) C0303611) =Indicator, Reagent, or Diagnostic Aid; Element, Ion, or Isotope =Tc element;
|
- 11. T-Cell Leukemia Translocation Altered Gene
- [This gene is putatively involved in the regulation of cell growth. ( NCI )] (UMLS (NCI) C1336599) TCTA;
TCTA Gene =Gene or Genome ;
| - 35. Tc 99m Dextran
- [A radiolabeled substance that is used in cancer diagnosis. ( NCI )] (UMLS (NCI) C0076028) =Carbohydrate; Indicator, Reagent, or Diagnostic Aid
|
- 12. T-Cell Leukemia Translocation Altered Gene Product
- [Ubiquitously expressed (highest in kidney) 103-aa 11-kDa T-Cell Leukemia Translocation Altered Gene Product is encoded by human TCTA Gene. (NCI) ( NCI )] (UMLS (NCI) C1336600) TCTA;
=Amino Acid, Peptide, or Protein; Biologically Active Substance | - 36. Tc 99m Human Serum Albumin Colloid
- [A colloid formulation of human serum albumin (HSA) labeled with Technetium-99m (Tc-99m) with diagnostic imaging properties. This HSA radioconjugate contains the gamma-emitting Tc99m, a metastable nuclide of molybdenum-99. A potential advantage of the Tc-99m-HSA suspension is its smaller colloid particle size compared to formulations containing either sulfur or tin, thereby allowing for enhanced imaging of the lymphatic draining pattern during lymphoscintigraphic or sentinel lymph node mapping procedures. ( NCI )] (UMLS (NCI) C0879625) Technetium Tc 99m Human Serum Albumin Colloid =Amino Acid, Peptide, or Protein; Pharmacologic Substance ;
|
- 13. T-Cell Leukemia, Homeobox 1 Gene
- [This gene plays a role in transcriptional regulation and organogenesis. Translocations in the gene are associated with acute T-cell leukemia. ( NCI )] (UMLS (NCI) C0920270) TLX1;
TLX1 Gene;
=Gene or Genome | - 37. Tc 99m LL2
- [A radioimmunoconjugate of the humanized IgG1 monoclonal antibody (MoAb) LL2 labeled with Technetium 99m (Tc-99m). Epratuzumab (MoAb LL2) recognizes CD22, a B-lymphocyte-restricted antigen expressed as a cytoplasmic protein in progenitor B cells, and as a cell surface protein in mature B cells. Tc-99m epratuzumab delivers gamma emission Tc-99m directly to B-lymphocyte lineage cells, thereby may be used in diagnosis or treatment purposes. ( NCI )] (UMLS (NCI) C0678085) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor
|
- 14. T-Cell Leukemia/Lymphoma 1B Gene
- [This gene plays a role in the development of B cells. It is also involved in regulation of cell differentiation, growth and survival. ( NCI )] (UMLS (NCI) C1336598) TCL1B;
TCL1B Gene =Gene or Genome ;
| - 38. Tc 99m Monoclonal Antibody 170
- [A radioimmunoconjugate of a murine whole immunoglobulin G monoclonal antibody MAb-170 labeled with Technetium 99m (Tc-99m). MAb-170, originally raised against a carbohydrate epitope (a synthetic Thomsen-Friedenreich antigen), has been found to have panadenocarcinoma affinity, including adenocarcinomas of breast, fallopian tube, colon, endometrium, prostate, bladder, liver, lung, and ovary. Tc-99m MAb-170 delivers gamma emission Tc-99m nuclide directly to adenocarcinoma tissues, thereby may be used in diagnostic or imaging purpose. ( NCI )] (UMLS (NCI) C0393033) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor
|
- 15. T-Cell Lymphoma Invasion and Metastasis 1 Gene
- [This gene is plays a role in signal transduction, apoptosis and cytoskeletal remodeling. ( NCI )] (UMLS (NCI) C0812248) TIAM1;
TIAM1 Gene =Gene or Genome | - 39. Tc 99m Sestamibi
- [Sestamibi is a large synthetic molecule of the isonitrile family, which can be labeled with Tc99m. It passes through cells membranes passively, collecting in cells with large numbers of mitochondria. It is often used for imaging of the thyroid and parathyroid. ( NCI )] (UMLS (NCI) C0162680) =Organic Chemical; Indicator, Reagent, or Diagnostic Aid
|
- 16. T-Cell Proliferation
- [An increase in the number of all, or specific subsets of, T-cells by cell growth and cell division during an immune response or during development. ( NCI )] (UMLS (NCI) C1155046) =Cell Function
| - 40. Tc 99m Sulfur Colloid
- [A gamma-emitting colloid used in scintillation scanning of the reticuloendothelial system (RES). After intravenous administration, technetium Tc 99m sulfur colloid is phagocytized by the reticuloendothelial system and concentrated in the liver, spleen, and bone marrow; detection/localization of phagocytized gamma ray-emitting colloid is performed with a gamma-ray scintillation camera. Scintillation scanning using technetium Tc 99m colloid sulfur helps determine the distribution and function of the RES and the extent to which tumor involves the RES. The RES includes cells types that can phagocytize and sequester inert particles and vital dyes; RES cell types include macrophages or macrophage precursors, specialized endothelial cells lining the sinusoids of the liver, spleen, and bone marrow, and reticular cells of lymphatic tissue and of bone marrow. ( NCI )] (UMLS (NCI) C0039419) =Indicator, Reagent, or Diagnostic Aid; Inorganic Chemical
|
- 17. T-Cell Proliferation of Uncertain Malignant Potential
- (UMLS (NCI) C1336550) =Neoplastic Process ;
| - 41. Tc element
- [first artificially produced element; technetium has the atomic symbol Tc, atomic number 43; all technetium isotopes are radioactive; technetium 99m has a half-life of about 6 hours and is used diagnostically as a radioactive imaging agent. ( CSP )] (UMLS (CSP) C0039411) =Element, Ion, or Isotope ;
=Elements, radioactive;
radioisotope;
heavy metal;
[DX201] IMAGING AGENTS (IN VIVO) RADIOPHARMACEUTICALS =Tc 99m;
Technetium Tc 99m Disofenin;
technetium Tc 99m teboroxime;
TECHNETIUM Tc 99m SODIUM PERTECHNETATE |
- 18. T-Cell Prolymphocytic Leukemia, Cerebriform Cell Variant
- (UMLS (NCI) C1336551) T-Cell Prolymphocytic Leukemia, Sezary Cell-like Variant =Neoplastic Process ;
| - 42. TCAR/TG
- (UMLS (NCI) C0281378) =Therapeutic or Preventive Procedure ;
|
- 19. T-Cell Prolymphocytic Leukemia, Small Cell Variant
- (UMLS (NCI) C1336552) =Neoplastic Process ;
| - 43. TCDF (tetrachlorodibenzofuran)
- [ ] (UMLS (CSP) C0599158) =Organic Chemical ;
|
- 20. T-Cell Receptor Alpha
- [One component of the alpha-beta T-cell receptor. Encoded by a locus on chromosome 14. Somatic recombination results in formation of the active gene. ( NCI )] (UMLS (NCI) C0087048) =Amino Acid, Peptide, or Protein; Immunologic Factor; Receptor
| - 44. TCF21 Gene
- [This gene plays a role in embryonic trancriptional regulation. ( NCI )] (UMLS (NCI) C1420638) Transcription Factor 21 Gene;
=Gene or Genome |
- 21. T-Cell Receptor Beta
- [One component of the alpha-beta T-cell receptor. Encoded by a locus on chromosome 7. Somatic recombination results in formation of the active gene. ( NCI )] (UMLS (NCI) C0087049) =Amino Acid, Peptide, or Protein; Immunologic Factor; Receptor
| - 45. TCF3
- [This gene plays a role in regulation of transcription. It is involved in the control of tissue-specific cell fate during embryogenesis. ( NCI )] (UMLS (NCI) C1336596) TCF3 Gene;
Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) Gene =Gene or Genome ;
|
- 22. T-Cell Receptor Delta
- [One component of the gamma-delta T-cell receptor. Encoded by a locus on chromosome 14. Somatic recombination results in formation of the active gene. ( NCI )] (UMLS (NCI) C0087050) =Amino Acid, Peptide, or Protein; Immunologic Factor; Receptor
| - 46. TCF7L2
- [This gene plays a role in signal transduction and regulation of transcription. ( NCI )] (UMLS (NCI) C1420644) TCF7L2 Gene;
Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) Gene =Gene or Genome |
- 23. T-Cell Receptor Gamma
- [One component of the gamma-delta T-cell receptor. Encoded by a locus on chromosome 7. Somatic recombination results in formation of the active gene. ( NCI )] (UMLS (NCI) C0087051) =Amino Acid, Peptide, or Protein; Immunologic Factor; Receptor
| - 47. TCR/ACK _ Automated equipment test code settings request
- (UMLS (HL7) C1549392) =Health Care Activity =Event Type;
|
- 24. T-Cell Receptor Gene
- [The T-cell antigen receptors consist of a heterodimer of integral membrane glycoproteins. Two distinct receptors exist, alpha/beta and gamma/delta. Alpha/beta receptors are found on helper and cytotoxic T-cells and are specific for antigenic peptides presented in association with MHC gene products. Gamma/delta receptors, found in association with CD3, directly recognize proteins and non-proteinacious phospho-ligands. Alpha/beta and gamma/delta are non-covalently associated with CD3-gamma, -delta, -epsilon, and -zeta proteins, forming the TCR-CD3 complex, which activate MAPKs and JNK1 through the CD3 antigens, the adaptor protein LAT, and tyrosine kinases LCK and ZAP70. The genes for T-cell receptor subunits are encoded by distinct gene elements that are assembled by somatic rearrangement during T-cell development. Translocations and inversions of these loci are observed in human T-cell leukemias and lymphomas. ( NCI )] (UMLS (NCI) C0524889) =Gene or Genome ;
| - 48. TCU/ACK _ Automated equipment test code settings update
- (UMLS (HL7) C1549391) =Health Care Activity =Event Type;
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