- 1. (201-Tl) Thallous Chloride
- [The chloride salt form of thallium-201, a cyclotron produced isotope use in diagnostic imaging. Thallous chloride TI-201 accumulates in myocardial cells and other tissues in an analogous way as potassium, and can be evaluated as a function of blood flow. By scintigraphic means, areas with decreased blood flow, consisting of ischemic cells, can be visualized due to decreased uptake of TI-201 in contrast to areas with normal blood flow. ( NCI )] (UMLS (NCI) C0305040) =Indicator, Reagent, or Diagnostic Aid; Inorganic Chemical ;
=thallium chloride;
[DX201] IMAGING AGENTS (IN VIVO) RADIOPHARMACEUTICALS =Thallous chloride Tl201 1 MIL;
Thallous chloride Tl201 1 MIL/ML;
Thallous chloride Tl201 2 MIL/ML;
| - 12. TLR1
- [This gene is involved in pathogen recognition and in the activation of innate immunity. ( NCI )] (UMLS (NCI) C1366477) TLR1 Gene;
Toll-Like Receptor 1 Gene;
=Gene or Genome ;
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- 2. T lymphocyte depletion therapy
- [ ] (UMLS (CSP) C1171367) =Therapeutic or Preventive Procedure ;
| - 13. TLR2
- [This gene plays a role in pathogen recognition and mediates the host response to gram-positive bacteria and yeast. ( NCI )] (UMLS (NCI) C1336634) TLR2 Gene;
Toll-Like Receptor 2 Gene =Gene or Genome ;
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- 3. T lymphocyte marker
- [ ] (UMLS (CSP) C0598072) =Amino Acid, Peptide, or Protein; Immunologic Factor
| - 14. TLR3
- [Expressed most in placenta, pancreas, and CD11c+ immature dendritic leukocytes by human TLR3 Gene (TLR Family), 904-aa 104-kDa (precursor) type I membrane protein Toll-Like Receptor 3 contains a TIR domain and 22 LRR repeats. Likely involved in host viral defense, TLR3 recognizes viral dsRNA and has a fundamental role in pathogen recognition and activation of innate immunity to microbial agents. Sharing structural and functional similarities, highly conserved TLRs recognize pathogen-associated molecular patterns expressed on infectious agents and mediate cytokine production necessary for effective immunity. TLR3 appears to act via MyD88 (TIR interaction) and TRAF6, leading to NF-Kappa-B activation and production of type I interferons. (NCI) ( NCI )] (UMLS (NCI) C1313494) Toll-Like Receptor 3;
=Amino Acid, Peptide, or Protein; Immunologic Factor; Receptor |
- 4. Tl198 isotope
- [ ] (UMLS (CSP) C0303318) =Element, Ion, or Isotope
| - 15. TLR3
- [This gene is involved in innate antiviral responses. ( NCI )] (UMLS (NCI) C1336635) TLR3 Gene;
Toll-Like Receptor 3 Gene =Gene or Genome ;
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- 5. Tl202 isotope
- [ ] (UMLS (CSP) C0303323) =Element, Ion, or Isotope
| - 16. TLR4
- [This gene is involved in the mediation of immune responses and in signal transduction events induced by lipopolysaccharide. ( NCI )] (UMLS (NCI) C1336636) TLR4 Gene;
Toll-Like Receptor 4 Gene =Gene or Genome ;
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- 6. Tl204 isotope
- [ ] (UMLS (CSP) C0303324) =Element, Ion, or Isotope
| - 17. TLR5
- [This gene plays a role in the mediation of cytokine production and immunity. ( NCI )] (UMLS (NCI) C1336637) TLR5 Gene;
Toll-Like Receptor 5 Gene =Gene or Genome ;
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- 7. TLC D-99
- (UMLS (NCI) C0701184) =Organic Chemical; Antibiotic ;
| - 18. TLR6
- [Expressed in monocytes, CD11c+ immature dendritic cells, and dermal endothelial cells by human TLR6 Gene (TLR Family), 796-aa 92-kDa (precursor) type I membrane protein Toll-Like Receptor 6 contains a TIR domain and 13 LRR repeats. Sharing structural and functional similarities, highly conserved TLRs recognize pathogen-associated molecular patterns expressed on infectious agents and mediate cytokine production necessary for effective immunity. Bound extracellularly to TLR2, TLR6 mediates cellular response to fungi and bacterial lipoproteins MALP-2, STF, PSM, and OspA-L. TLR6 acts via MyD88 (TIR interaction) and TRAF6, leading to NF-kappa-B activation, cytokine secretion, and the inflammatory response. (NCI) ( NCI )] (UMLS (NCI) C0768454) Toll-Like Receptor 6;
=Amino Acid, Peptide, or Protein; Immunologic Factor; Receptor |
- 8. TLI Vaccine
- [A vaccine consisting of a preparation of allogeneic lymphocytes that encode a gene for telomerase. In transgenic lymphocyte immunization, the transgenic cells are infused into the patient, where they serve as antigen- presenting cells (APCs) with the dual function of antigen synthesis and presentation. Vaccination produces an immune response targeting cancer cells expressing telomerase. (NCI04) ( NCI )] (UMLS (NCI) C1327996) Transgenic Lymphocyte Immunization Vaccine =Pharmacologic Substance; Immunologic Factor
| - 19. TLR6
- [This gene is involved in immune responses through nuclear factor kappa-B signal transduction. ( NCI )] (UMLS (NCI) C1336638) TLR6 Gene;
Toll-Like Receptor 6 Gene =Gene or Genome ;
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- 9. Tlingit
- (UMLS (NCI) C0682118) =Population Group =Tlingit-Haida;
| - 20. TLR7
- [This gene plays a role in receptor signaling and in innate immune responses. ( NCI )] (UMLS (NCI) C1336639) TLR7 Gene;
Toll-Like Receptor 7 Gene =Gene or Genome ;
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- 10. TLK286
- [A substance that is being studied as a treatment for cancer. It belongs to the family of drugs called glutathione analogs. ( NCI )] (UMLS (NCI) C1258106) =Amino Acid, Peptide, or Protein; Pharmacologic Substance
| - 21. TLR8
- [This gene plays a role in receptor signaling and in immune responses. ( NCI )] (UMLS (NCI) C1336640) TLR8 Gene;
Toll-Like Receptor 8 Gene =Gene or Genome ;
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- 11. TLR protein
- [activates signal transduction pathways that result in transcriptional regulation and stimulate immune function; activates innate immunity as well as stimulating the antigen-specific immune response and triggering the inflammatory response; conveys signals stimulated by factors such as lipopolysaccharides, bacterial lipoproteins, peptidoglycans and also CpG nucleic acids. ( CSP )] (UMLS (CSP) C0670896) =Amino Acid, Peptide, or Protein; Receptor =Cell Surface Receptor;
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