- 1. (+)-6-((4-Chlorophenyl)-1H-1,2,4-triazol-1-ylmethyl)-1-methyl-1H-benzotriazole
- [A hormone therapy drug used to decrease the production of estrogen. ( NCI )] (UMLS (NCI) C0286224) =Organic Chemical; Pharmacologic Substance
| - 51. 7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-2-naphthacenecarboxamide Monohydrochloride
- [The hydrochloride salt form of demeclocycline, a broad-spectrum, tetracycline derivative exhibiting antimicrobial activity. Demeclocycline hydrochloride binds reversibly to the 30S ribosomal subunit, thereby blocking the binding of aminoacyl-tRNA to the A-site of the mRNA-ribosome complex. This inhibits protein synthesis. In addition, this agent inhibits ADH-induced water reabsorption in the kidneys, thereby causing diuresis. ( NCI )] (UMLS (NCI) C0282125) =Organic Chemical; Antibiotic ;
=7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-2-naphthacenecarboxamide;
=DEMECLOCYCLINE HYDROCHLORIDE 150 MG;
DEMECLOCYCLINE HYDROCHLORIDE 300 MG;
|
- 2. (+-)-1-(3-Chlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone Hydrochloride
- [The hydrochloride salt of an aminoketone antidepressant. The molecular mechanism of the antidepressant effect of bupropion is unknown. This agent does not inhibit monoamine oxidase and, compared to classical tricyclic antidepressants, is a weak blocker of the neuronal uptake of serotonin and norepinephrine. Buproprion also weakly inhibits the neuronal re-uptake of dopamine. ( NCI )] (UMLS (NCI) C0700563) =Organic Chemical; Pharmacologic Substance =1-Propanone, 1-(3-Chlorophenyl)-2-((1,1-dimethylethyl)amino)-;
=BUPROPION HYDROCHLORIDE 100 MG;
BUPROPION HYDROCHLORIDE 75 MG;
BUPROPION HYDROCHLORIDE 150 MG | - 52. 7-Chloro-5-(2-chlorophenyl)-1, 3-Dihydro-3-Hydroxy-1,4- Benzodiazepin-2-one
- [7-chloro-5-(2-chlorophenyl)-1, 3-dihydro-3-hydroxy-1,4- benzodiazepin-2-one. ( CSP )] (UMLS (NCI) C0024002) =Organic Chemical; Pharmacologic Substance =benzodiazepine;
Benzodiazepinones;
tranquilizer;
[CN302] BENZODIAZEPINE DERIVATIVE, SEDATIVES/HYPNOTICS =LORAZEPAM 1 MG;
LORAZEPAM 2 MG;
LORAZEPAM 2 MG/ML;
LORAZEPAM 0.5 MG;
LORAZEPAM 4 MG/ML |
- 3. (+-)-1-(4-(4-Chlorophenyl)-2-((2,6-dichlorophenyl)thio)butyl)-1H-imidazole Mononitrate
- [The nitrate salt form of butaconazole, a synthetic imidazole derivative with fungistatic properties. Butoconazole nitrate interferes with steroid biosynthesis by inhibiting the conversion of lanosterol to ergosterol, thereby changing the fungal cell membrane lipid composition. This alters cell permeability and leads to growth inhibition. Butaconazole nitrate is active against many dermatophytes and yeasts. It also contains antibacterial effects against some gram-positive organisms. ( NCI )] (UMLS (NCI) C0107509) =Organic Chemical; Pharmacologic Substance =butoconazole;
=BUTOCONAZOLE NITRATE 2 % | - 53. 7-Chloro-7-deoxylincomycin
- [A semisynthetic broad spectrum antibiotic produced by chemical modification of the parent compound lincomycin. Clindamycin dissociates peptidyl-tRNA from the bacterial ribosome, thereby disrupting bacterial protein synthesis. (NCI04) ( NCI )] (UMLS (NCI) C0008947) =Carbohydrate; Antibiotic =LINCOMYCIN;
[AM350] LINCOMYCINS;
[DE752] ANTIACNE AGENTS, TOPICAL;
[GU300] ANTI-INFECTIVES, VAGINAL =7(S)-Chloro-7-deoxylincomycin 2-phosphate;
7-Chloro-7-deoxylincomycin Hydrochloride;
Clindamycin Palmitate Hydrochloride;
|
- 4. (-)-2-(2-Chlorophenyl)-5,7-dihydroxy-8-[(3R,4S)-3-hydroxy-1-methyl-4-piperidinyl]-4H-1-benzopyran-4-one Hydrochloride
- [antineoplastic cyclin dependent kinase inhibitor. ( CSP )] (UMLS (NCI) C0281603) =Organic Chemical; Pharmacologic Substance =[AN000] ANTINEOPLASTICS;
enzyme inhibitor;
flavone;
| - 54. 7-Chloro-7-deoxylincomycin Hydrochloride
- [The hydrochloride salt form of clindamycin, a lincomycin antibiotic with antibacterial activity. Clindamycin hydrochloride exerts its antibacterial effect by binding to the 50S subunits of bacterial ribosomes, thereby interfering with peptidyl transferase activity in the elongation process of protein synthesis. As a result, this agent prevents bacterial cell growth. ( NCI )] (UMLS (NCI) C0282105) =Carbohydrate; Antibiotic ;
=7-Chloro-7-deoxylincomycin;
7(S)-Chloro-7-deoxylincomycin 2-phosphate =CLINDAMYCIN HYDROCHLORIDE 150 MG;
CLINDAMYCIN HYDROCHLORIDE 75 MG;
CLINDAMYCIN HYDROCHLORIDE 300 MG |
- 5. (-)-Cholesterol
- [C27H46O, the major fatty steroid alcohol of vertebrate animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils. ( CSP )] (UMLS (NCI) C0008377) =Steroid; Biologically Active Substance ;
=cholestane compound;
Cholestenes;
sterol;
Unclassified Ingredient Preparations =hydroxycholesterol;
cholesterol oxide;
SALICYLIC ACID 40% OINTMENT(GM);
BASLE CREAM,TOP;
ALUMINUM ACETATE/ZINC OXIDE PASTE,TOP;
CHOLESTEROL 3 %;
| - 55. 8-Chloro Cyclic AMP
- [A substance that is being studied as an anticancer drug. It is an analogue of a substance that occurs naturally in the body (cyclic adenosine monophosphate). ( NCI )] (UMLS (NCI) C0050063) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
|
- 6. (CH3)2CHCH2CH3
- [An organic, branched-chain alkane with five carbon atoms. ( NCI )] (UMLS (NCI) C0083072) =Organic Chemical
| - 56. 8-Chloro-6-(2-fluorophenyl)-1-Methyl- 4H- Imidazo(1,5a)(1,4)Benzodiazepine
- [8-chloro-6-(2-fluorophenyl)-1-methyl- 4H- imidazo(1,5a)(1,4)benzodiazepine; short acting benzodiazepine sedative with high liability for abuse; used for preanesthesia sedation (USP lists as an injectable anesthetic). ( CSP )] (UMLS (NCI) C0026056) =Organic Chemical; Pharmacologic Substance =benzodiazepine;
[CN300] SEDATIVES/HYPNOTICS;
[CN302] BENZODIAZEPINE DERIVATIVE, SEDATIVES/HYPNOTICS;
=MIDAZOLAM HYDROCHLORIDE;
|
- 7. 1-(2-chloroethyl)-1-nitroso-3-(D-glucos-2-yl)urea
- [A glucose-linked chloroethylnitrosourea with potential antineoplastic activity. Chlorozotocin alkylates DNA and proteins, induces the formation of interstrand DNA and DNA-protein crosslinks, and causes DNA strand breakage, thereby damaging DNA and resulting in cell death. This agent has been shown to exhibit antitumor and immunomodulatory effects in cell lines and animal models. Chlorozotocin is a mutagen and is less myelotoxic than other nitrosoureas. (NCI04) ( NCI )] (UMLS (NCI) C0055465) =Organic Chemical; Antibiotic
| - 57. 8-Chloro-6-phenyl-4H-(1,2,4)triazolo-(4,3-a)(1,4)benzodiazepine
- [A triazolo-benzodiazepine with anxiolytic, anticonvulsant, hypnotic, and muscle relaxant properties. Estazolam binds to the gamma-aminobutyric acid (GABA) receptor at a site distinct from the inhibitory neurotransmitter GABA binding site in the limbic system of the central nervous system (CNS). This binding leads to an opening of the chloride channels, which allows the flow of chloride ions into the neuron, hyperpolarizes the neuronal membrane, inhibits neuronal firing, and leads to a decrease in neuronal excitability. ( NCI )] (UMLS (NCI) C0014892) =Organic Chemical; Pharmacologic Substance =benzodiazepine;
[CN302] BENZODIAZEPINE DERIVATIVE, SEDATIVES/HYPNOTICS =ESTAZOLAM 1 MG;
ESTAZOLAM 2 MG |
- 8. 1-(2-Chloroethyl)-3-(2,6-Dioxo-3-Piperidyl)-1-Nitrourea
- [A chloroethylnitrosourea compound and an alkylating agent with antineoplastic property. PCNU inhibits DNA synthesis by alkylating DNA and causing DNA cross links, thereby inducing apoptosis. In addition, this agent may be associated with pulmonary, hepatic, and hematologic toxicities. Unlike other nitrosoureas, PCNU has strong alkylating while weak carbamoylating activity. ( NCI )] (UMLS (NCI) C0070165) =Organic Chemical; Pharmacologic Substance
| - 58. 9-Chloro-6alpha-fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 21-pivalate
- [A glucocorticoid receptor agonist with metabolic, anti-inflammatory, and immunosuppressive activity. Clocortolone pivalate exerts its effect by interacting with specific intracellular receptors and subsequently binds to DNA to modify gene expression. This results in an induction of the synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions are accomplished. ( NCI )] (UMLS (NCI) C0055900) =Steroid; Pharmacologic Substance; Hormone =Fluocortolone;
CLOCORTOLONE =CLOCORTOLONE PIVALATE 0.1 % |
- 9. 1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea
- [An anticancer drug that belongs to the family of drugs called alkylating agents. ( NCI )] (UMLS (NCI) C0036637) =Organic Chemical; Pharmacologic Substance ;
| - 59. C10H12CaN2Na2O8
- [Contracted name for a salt of ethylenediaminetetraacetate, an agent used as a chelator of lead and some other heavy metals. C10H12CaN2Na2O8. ( NCI )] (UMLS (NCI) C0006692) =Organic Chemical; Pharmacologic Substance; Indicator, Reagent, or Diagnostic Aid ;
=EDETATE;
=EDETATE CALCIUM DISODIUM 0.05 MG/ML;
EDETATE CALCIUM DISODIUM 200 MG/ML;
|
- 10. 1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea
- [cytotoxic alkylating agent of the nitrosourea group used as an antineoplastic. ( CSP )] (UMLS (NCI) C0023972) =Organic Chemical; Pharmacologic Substance =[AN000] ANTINEOPLASTICS;
nitrosourea;
Antineoplastic Alkylating Agent;
=LOMUSTINE 10 MG;
LOMUSTINE 100 MG;
LOMUSTINE 40 MG;
LOMUSTINE 300 MG;
| - 60. C3H
- (UMLS (NCI) C0025920) =Mammal ;
|
- 11. 1-(4-chlorobenzoyl)-5-methoxy- 2-methyl-1-H-indole-3-acetic acid
- [non-steroidal anti-inflammatory agent that inhibits the enzyme cyclooxygenase necessary for the formation of prostaglandins and other autacoids; also inhibits the motility of polymorphonuclear leukocytes. ( CSP )] (UMLS (NCI) C0021246) =Organic Chemical; Pharmacologic Substance =Indole;
cyclooxygenase inhibitor;
methoxyindole;
[MS102] NONSALICYLATE NSAIS, ANTIRHEUMATIC;
immunomodulator;
=KETOROLAC TROMETHAMINE;
Indomethacin Sodium;
INDOMETHACIN POWDER (GM);
Indomethacin Sodium;
INDOMETHACIN 25 MG;
INDOMETHACIN 25 MG/5ML;
INDOMETHACIN 50 MG;
INDOMETHACIN 75 MG;
| - 61. C6H12CLN3O4S
- [A chloroethylating nitrosourea that causes DNA cross-linking, inhibiting DNA replication. (NCI) ( NCI )] (UMLS (NCI) C0067099) =Organic Chemical; Pharmacologic Substance ;
|
- 12. 1-(5-Chloro-3-(2-chlorophenyl)-1-(3,4-dimethoxybenzenesulfonyl)-3-hydroxy-2,3-dihydro-1H-indole-2-carbonyl)pyrrolidine-2-carboxamide
- (UMLS (NCI) C0218068) =Organic Chemical; Pharmacologic Substance ;
| - 62. CH
- [large republic in eastern and central Asia, known also as the People's Republic of China; capital city is Beijing. ( CSP )] (UMLS (NCI) C0008115) =Geographic Area ;
=Asia;
|
- 13. 1-Chloro-2,3-epoxypropane
- [A volatile and flammable, clear, colorless, liquid, chlorinated cyclic ether with an irritating, chloroform-like odor that emits toxic fumes of hydrochloric acid and other chlorinated compounds when heated to decomposition. Epichlorohydrin is used in the manufacture of epoxy resins, synthetic glycerin and elastomers. Exposure to epichlorohydrin irritates the eyes, skin and respiratory tract, and can cause chemical pneumonitis, pulmonary edema, and renal lesions. This substance also affects the blood. Epichlorohydrin is reasonably anticipated to be a human carcinogen and may be associated with an increased risk of developing respiratory cancer. (NCI05) ( NCI )] (UMLS (NCI) C0014486) =Organic Chemical; Hazardous or Poisonous Substance ;
| - 63. CH
- [A country in Central Europe, east of France, north of Italy. (NCI) ( NCI )] (UMLS (NCI) C0039021) =Geographic Area
|
- 14. 1-Chloroisobutylene
- [A clear, colorless, highly volatile and flammable liquid chlorinated hydrocarbon that emits highly toxic fumes of hydrochloric acid and other chlorinated compounds when heated to decomposition. Dimethylvinyl chloride is exclusively used for research purposes in organic synthesis and in the production of isobutylene compounds. This substance is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0044333) =Organic Chemical; Pharmacologic Substance ;
| - 64. CH ENLARGMNT LACRIM GLND
- (UMLS (ICD9CM) C1300133) Chronic enlargement of lacrimal gland =Disease or Syndrome
|
- 15. 1-[(2-Chlorophenyl)diphenylmethyl]-1H-imidazole
- [A synthetic, imidazole derivate with broad-spectrum, antifungal activity. Clotrimazole inhibits biosynthesis of sterols, particularly ergosterol, an essential component of the fungal cell membrane, thereby damaging and affecting the permeability of the cell membrane. This results in leakage and loss of essential intracellular compounds, and eventually causes cell lysis. ( NCI )] (UMLS (NCI) C0009074) =Organic Chemical; Pharmacologic Substance =imidazole;
[DE102] ANTIFUNGAL, TOPICAL;
[GU300] ANTI-INFECTIVES, VAGINAL;
[NT900] NASAL AND THROAT, TOPICAL, OTHER =CLOTRIMAZOLE 10 MG;
CLOTRIMAZOLE 100 MG;
CLOTRIMAZOLE 200 MG;
CLOTRIMAZOLE 1 % | - 65. CH OB ASTHMA W STAT ASTH
- [ ] (UMLS (ICD9CM) C0375334) =Disease or Syndrome ;
|
- 16. 1-[(4-Chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine
- [A synthetic piperazine with anti-emetic, sedative and histamine H1antagonistic properties. Meclizine blocks the H1 histamine receptor and prevents the symptoms that are caused by histamine activity on capillaries, bronchial and gastrointestinal smooth muscles, including vasodilation, increased capillary permeability, bronchoconstriction, and spasmodic contraction of gastrointestinal smooth muscles. Meclizine hydrochloride may exert its antiemetic effects by its anticholinergic actions or due to a direct effect on the medullary chemoreceptive trigger zone. ( NCI )] (UMLS (NCI) C0025039) =Organic Chemical; Pharmacologic Substance ;
=Benzhydryl Compounds;
Piperazines;
[CN550] ANTIVERTIGO AGENTS;
=1-[(4-Chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine Dihydrochloride Monohydrate | - 66. CH OBST ASTH W (AC) EXAC
- (UMLS (ICD9CM) C1176341) Chronic obstructive asthma, with acute exacerbation =Disease or Syndrome ;
|
- 17. 1-[(4-Chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine Dihydrochloride Monohydrate
- [The hydrochloride salt form of meclizine, a synthetic piperazine with anti-emetic, sedative and histamine H1 antagonistic properties. Meclizine hydrochloride blocks the H1 histamine receptor and prevents the symptoms that are caused by histamine activity on capillaries, bronchial and gastrointestinal smooth muscles, including vasodilation, increased capillary permeability, bronchoconstriction, and spasmodic contraction of gastrointestinal smooth muscles. Meclizine hydrochloride may exert its antiemetic effects by its anticholinergic actions or due to a direct effect on the medullary chemoreceptive trigger zone. ( NCI )] (UMLS (NCI) C0282227) =Organic Chemical; Pharmacologic Substance =1-[(4-Chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine;
=MECLIZINE HYDROCHLORIDE 15 MG;
MECLIZINE HYDROCHLORIDE 50 MG;
MECLIZINE HYDROCHLORIDE 12.5 MG;
MECLIZINE HYDROCHLORIDE 25 MG;
MECLIZINE HYDROCHLORIDE 30 MG;
| - 67. CH PL COCCIDIOIDOMYCOSIS
- [ ] (UMLS (ICD9CM) C0339963) =Disease or Syndrome ;
|
- 18. 1-[2-{(4-chloro-phenyl)methoxy}-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole Mononitrate
- [An imidazole derivative and broad-spectrum antimycotic agent with fungistatic properties. Econazole nitrate inhibits biosynthesis of ergosterol, thereby damaging the fungal cell wall membrane and altering its permeability which leads to a loss of essential intracellular components. In addition, econazole nitrate inhibits biosynthesis of triglycerides and phospholipids and inhibits oxidative and peroxidative enzyme activity which may contribute to cellular necrosis and cell death. Econazole nitrate is also active against some gram positive bacteria. This antifungal agent is used in the treatment various dermatomycoses. ( NCI )] (UMLS (NCI) C0546862) =Organic Chemical; Pharmacologic Substance =ECONAZOLE;
=ECONAZOLE NITRATE 1 %;
| - 68. Ch-1PTPase
- [Alternative alpha, beta, gamma, and delta isoforms of Protein Tyrosine Phosphatase PCPTP1 are expressed in brain, kidney, placenta, small intestine, stomach, uterus, or prostate by human PTPRR Gene (PTP Family). Type I membrane protein receptor-type PTP isoforms alpha and beta possess an extracellular region, a single transmembrane region, and a single intracellular catalytic domain. Cytoplasmic nonreceptor-type PTP isoforms gamma and delta contain 1 PTP domain and locate in the perinuclear area. PTPRR sequesters inactive MAPKs, such as MAPK1, MAPK3, and MAPK14, in the cytoplasm. MAPKs likely bind to a dephosphorylated kinase interacting motif, phosphorylation of which by Protein Kinase A complex releases MAPKs for activation and nuclear translocation. Mouse Ptprr is expressed predominately in the brain and regulates MAP kinase activity and localization. (NCI) ( NCI )] (UMLS (NCI) C0963314) EC-PTP;
NC-PTPCOM1;
PCPTP1;
Protein Tyrosine Phosphatase Cr1PTPase;
Protein Tyrosine Phosphatase NC-PTPCOM1;
Protein Tyrosine Phosphatase Receptor Type R;
Protein Tyrosine Phosphatase-PCPTP1;
PTPBR7;
PTPRR;
PTP-SL;
Receptor Type Protein Tyrosine Phosphatase R =Amino Acid, Peptide, or Protein; Enzyme; Receptor |
- 19. 1-[4-Chloroanilino]-4-[4-pyridylmethyl]phthalazine Succinate
- [An orally bioavailable anilinophthalazine with potential antineoplastic activity. Vatalanib binds to and inhibits the protein kinase domain of vascular endothelial growth factor receptors 1 and 2; both receptor tyrosine kinases are involved in angiogenesis. This agent also binds to and inhibits related receptor tyrosine kinases, including platelet-derived growth factor (PDGF) receptor, c-Kit, and c-Fms. ( NCI )] (UMLS (NCI) C0912586) 1-Phthalazinamine, N-(4-chlorophenyl)-4-(4-pyridinylmethyl)-, butanedioate (1:1);
Butanedioic Acid, Compd. with N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine (1:1);
PTK 787/ZK 222584;
VATALANIB =Organic Chemical; Pharmacologic Substance | - 69. Ch14.18
- [A chimeric mouse/human monoclonal antibody with potential antineoplastic activity. Monoclonal antibody Ch14.18 binds to the ganglioside GD2 and induces antibody-dependent cell-mediated cytotoxicity and complement-dependent cytotoxicity against GD2-expressing tumor cells. GD2 is overexpressed in malignant melanoma, neuroblastoma, osteosarcoma, and small cell carcinoma of the lung. (NCI04) ( NCI )] (UMLS (NCI) C0281581) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor
|
- 20. 10-((3-Chloro-4-methoxyphenyl)methyl)-6-methyl-3-(2-methylpropyl)-16-(1-(3-phenyloxiranyl)ethyl)-1,4-dioxa-8,11-diazacyclohexadec-13-ene-2,5,9,12-tetrone
- [The cryptophycins are a family of 16-membered macrolide antimitotic agents isolated from the cyanobacteria Nostoc sp. The mechanism of anticancer activity of the cryptophycins has been associated with their destabilization of microtubules and induction of bcl-2 phosphorylation leading to apoptosis. Cryptophycins demonstrated activity against the wide spectrum of solid tumors including those that overexpress the multidrug resistance efflux pump P-glycoprotein. (NCI) ( NCI )] (UMLS (NCI) C0257217) =Amino Acid, Peptide, or Protein; Pharmacologic Substance
| - 70. CHAGAS DIS OF OTH ORGAN
- [ ] (UMLS (ICD9CM) C0153125) =Disease or Syndrome
|
- 21. 10-chloro-4-hydroxy-6-methyl-2-phenyl-3,6-diazabicyclo[5.4.0]undeca-2,8,10,12-tetraen-5-one
- [A benzodiazepine derivative with antidepressant, sedative, hypnotic and anticonvulsant properties. Temazepam potentiates the inhibitory activities of gamma-aminobutyric acid (GABA) by binding to the GABA receptor, located in the limbic, neocortical and mesencephalic reticular system. This increases the frequency of chloride channel opening events, allowing the flow of chloride ions into the neuron leading to membrane hyperpolarization and decreases neuronal excitability. ( NCI )] (UMLS (NCI) C0039468) =Organic Chemical; Pharmacologic Substance =Benzodiazepinones;
[CN302] BENZODIAZEPINE DERIVATIVE, SEDATIVES/HYPNOTICS =TEMAZEPAM 15 MG;
TEMAZEPAM 30 MG;
TEMAZEPAM 7.5 MG;
| - 71. CHAGAS DISEASE NOS
- (UMLS (ICD9CM) C0007932) =Disease or Syndrome
|
- 22. 2-(4-Chlorophenoxy)-2-methylpropanoic acid ethyl ester
- [fibric acid derivative used in the treatment of hyperlipoproteinemia and hypertriglyceridemia. ( CSP )] (UMLS (NCI) C0009002) =Organic Chemical; Pharmacologic Substance ;
=[CV350] ANTILIPEMIC AGENTS;
butyrate;
Clofibric Acid;
chlorophenoxyacetate | - 72. chain (Gunter's chain)
- [4 [rd_br] ( HL7V3.0 )] (UMLS (HL7) C1552927) =Quantitative Concept =UnitOfMeasureAtomInsens;
UnitOfMeasureAtomSens |
- 23. 2-Chlorallyl Diethyldithiocarbamate
- [A synthetic, amber oil that is slightly soluble in water and soluble in most organic solvents. Sulfallate products are no longer used in the United States. Therefore, the potential for human exposure is low. When heated to decomposition, sulfallate emits toxic fumes of hydrochloric acid, nitrogen, and sulfur oxides. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0054976) =Organic Chemical; Pharmacologic Substance ;
| - 73. chain (Gunter's or Surveyor's)
- [4 [rd_us] ( HL7V3.0 )] (UMLS (HL7) C1552916) =Quantitative Concept =UnitOfMeasureAtomInsens;
UnitOfMeasureAtomSens |
- 24. 2-Chloro-1,3-butadiene
- [A colorless, flammable, carcinogenic, chlorinated hydrocarbon with a pungent, ethereal odor. Chloroprene is used as a chemical intermediate in the manufacture of neoprene rubber. Exposure to this substance causes damage to the skin, lungs, CNS, kidneys, liver and depression of the immune system. Chloroprene is a mutagen and carcinogen in animals and is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0008267) =Organic Chemical; Hazardous or Poisonous Substance ;
| - 74. chain (Ramden's or Engineer's)
- [100 [ft_us] ( HL7V3.0 )] (UMLS (HL7) C1552918) =Quantitative Concept =UnitOfMeasureAtomInsens;
UnitOfMeasureAtomSens |
- 25. 2-Chloro-1-(difluoromethoxy)-1,1,2-trifluoroethane
- [extremely stable inhalation anesthetic that allows rapid adjustments of anesthesia depth with little change in pulse or respiratory rate. ( CSP )] (UMLS (NCI) C0014277) =Organic Chemical; Pharmacologic Substance ;
=[CN200] ANESTHETICS;
Methyl Ethers;
[CN201] ANESTHETICS INHALATION;
haloether =ENFLURANE 99.9 % | - 75. chalastodermia
- [group of connective tissue diseases in which skin hangs in loose pendulous folds; believed to be associated with decreased elastic tissue formation as well as an abnormality in elastin formation; usually a genetic disease, but acquired cases have been reported. ( CSP )] (UMLS (CSP) C0010495) =Disease or Syndrome =Connective Tissue Disease;
Genetic Condition;
Cutaneous Disorder;
Skin Diseases, Genetic |
- 26. 2-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)-phenothiazine
- [phenothiazine derivative used chiefly as an antiemetic. ( CSP )] (UMLS (NCI) C0033229) =Organic Chemical; Pharmacologic Substance =[GA700] ANTIEMETICS;
Phenothiazine;
[CN700] ANTIPSYCHOTICS;
=2-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)phenothiazine Edisylate;
Prochlorperazine Dimaleate;
2-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)phenothiazine Edisylate;
Prochlorperazine Dimaleate;
PROCHLORPERAZINE 10 MG;
PROCHLORPERAZINE 2.5 MG;
PROCHLORPERAZINE 25 MG;
PROCHLORPERAZINE 5 MG/ML;
PROCHLORPERAZINE 5 MG | - 76. CHALAZION
- [A non-neoplastic cyst of the MEIBOMIAN GLANDS of the eyelid. ( MSH )] (UMLS (ICD9CM) C0007933) =Disease or Syndrome =cyst;
DISORDER OF EYELID NOS |
- 27. 2-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)phenothiazine Edisylate
- [The edisylate salt form of prochlorperazine, a derivative of phenothiazine with antipsychotic and antiemetic properties. Prochlorperazine edisylate blocks postsynaptic dopamine receptors in cortical and limbic areas of the brain, thereby preventing the excess of dopamine in the brain. This leads to a reduction in psychotic symptoms, including hallucinations and delusions. Prochlorperazine edisylate appears to exert its antiemetic activity by blocking the dopamine and histamine receptors in the chemical trigger zone (CTZ) in the brain, thereby relieving nausea and vomiting. ( NCI )] (UMLS (NCI) C0033230) =Organic Chemical; Pharmacologic Substance =2-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)-phenothiazine;
=PROCHLORPERAZINE EDISYLATE 5 MG/ML;
PROCHLORPERAZINE EDISYLATE 5 MG/5ML;
| - 77. CHALAZION EXCISION
- [ ] (UMLS (ICD9CM) C0176144) =Therapeutic or Preventive Procedure
|
- 28. 2-Chloro-10-(3-(dimethylamino)propyl)phenothiazine
- [prototypical phenothiazine antipsychotic drug; antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking dopamine receptors; chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup. ( CSP )] (UMLS (NCI) C0008286) =Organic Chemical; Pharmacologic Substance ;
=Phenothiazine;
[CN700] ANTIPSYCHOTICS;
[CN701] PHENOTHIAZINES/RELATED, ANTIPSYCHOTICS;
=2-Chloro-10-(3-(dimethylamino)propyl)phenothiazine Monohydrochloride;
CHLORPROMAZINE 100 MG;
CHLORPROMAZINE 25 MG | - 78. Chalkyitsik Village
- (UMLS (HL7) C1550824) =Population Group =NativeEntityAlaska;
|
- 29. 2-Chloro-10-(3-(dimethylamino)propyl)phenothiazine Monohydrochloride
- [The hydrochloride salt form of chlorpromazine, a phenothiazine and traditional antipsychotic agent with anti-emetic activity. Chlorpromazine hydrochloride exerts its antipsychotic effect by blocking postsynaptic dopamine receptors in cortical and limbic areas of the brain, thereby preventing the excess of dopamine in the brain. This leads to a reduction in psychotic symptoms, such as hallucinations and delusions. Chlorpromazine hydrochloride appears to exert its anti-emetic activity by blocking the dopamine receptors in the chemical trigger zone (CTZ) in the brain, thereby relieving nausea and vomiting. ( NCI )] (UMLS (NCI) C0355077) =Organic Chemical; Pharmacologic Substance =2-Chloro-10-(3-(dimethylamino)propyl)phenothiazine;
=CHLORPROMAZINE HYDROCHLORIDE 25 MG;
CHLORPROMAZINE HYDROCHLORIDE 100 MG;
CHLORPROMAZINE HYDROCHLORIDE 10 MG;
CHLORPROMAZINE HYDROCHLORIDE 10 MG/5ML;
CHLORPROMAZINE HYDROCHLORIDE 150 MG;
CHLORPROMAZINE HYDROCHLORIDE 200 MG;
CHLORPROMAZINE HYDROCHLORIDE 30 MG;
CHLORPROMAZINE HYDROCHLORIDE 30 MG/ML;
CHLORPROMAZINE HYDROCHLORIDE 75 MG;
CHLORPROMAZINE HYDROCHLORIDE 50 MG;
CHLORPROMAZINE HYDROCHLORIDE 100 MG/ML;
CHLORPROMAZINE HYDROCHLORIDE 25 MG/ML;
| - 79. chalone
- [Peptides that inhibit mitosis (ANTIMITOTICS). During the 1960's the term referred to crude extracts that inhibited cell proliferation; the activity was later attributed to PYROGLUTAMATE type oligopeptides. ( MSH )] (UMLS (CSP) C0007937) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
|
- 30. 2-Chloro-11-(4-methyl-1-piperazinyl)dibenz(b,f)(1,4)oxazepine Succinate(1:1)
- [The succinate salt form of loxapine, a tricyclic dibenzoxazepine antipsychotic agent with antiemetic, sedative, anticholinergic, and antiadrenergic actions. Loxapine succinate exerts its actions by blocking the dopamine receptors at postsynaptic receptor sites in the limbic system, cortical system and basal ganglia, thereby reducing the hallucinations and delusions that are associated with schizophrenia. This agent also exerts extrapyramidal side effects. ( NCI )] (UMLS (NCI) C0024057) =Organic Chemical; Pharmacologic Substance ;
=LOXAPINE;
=LOXAPINE SUCCINATE 10 MG;
LOXAPINE SUCCINATE 25 MG;
LOXAPINE SUCCINATE 50 MG;
LOXAPINE SUCCINATE 5 MG;
| - 80. Chamber of the Eye
- (UMLS (NCI) C0459556) =Body Space or Junction
|
- 31. 2-Chloro-4-Phenylphenol
- (UMLS (NCI) C0045999) =Organic Chemical; Pharmacologic Substance ;
| - 81. CHAMOCA
- (UMLS (NCI) C0279969) =Therapeutic or Preventive Procedure
|
- 32. 2-Chloro-9-(2-deoxy-2-fluoroarabinofuranosyl)adenine
- [A substance that is being studied as a treatment for cancer. It belongs to the family of drugs called nucleoside analogs. ( NCI )] (UMLS (NCI) C0092777) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
| - 82. chamomile
- [Common name for several daisy-like plants (MATRICARIA; TRIPLEUROSPERMUM; ANTHEMIS; CHAMAEMELUM) native to Europe and Western Asia, now naturalized in the United States and Australia. ( MSH )] (UMLS (CSP) C0752226) =Plant
|
- 33. 2-Chloroethyl-3-Sarcosinamide-1-Nitrosourea
- [An anticancer drug that belongs to the family of drugs called alkylating agents. ( NCI )] (UMLS (NCI) C0045644) =Organic Chemical; Pharmacologic Substance ;
| - 83. Chamomile
- [The flower-heads of either the plant Anthemis nobilis or the plant Matricaria chamomilla. Chamomile has a warm aromatic odour and a very bitter taste and contains volatile oils which are a mixture of butyl and amyl angelates and valerates. Due to its coumarin constituents, large doses may interfere with coagulation. (NCI04) ( NCI )] (UMLS (NCI) C0439963) =Organic Chemical; Pharmacologic Substance =Unclassified Ingredients;
Inactive Ingredient Preparations |
- 34. 21-Chloro-6alpha,9-difluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17-propionate
- [The propionate salt form of halobetasol, a synthetic corticosteroid with anti-inflammatory, antipruritic and vasoconstrictor activities. Halobetasol, a topical steroid, diffuses across cell membranes to interact with cytoplasmic corticosteroid receptors located in both the dermal and intradermal cells, thereby activates gene expression of anti-inflammatory proteins mediated via corticosteroid receptor respond element. Specifically, this agent induces phospholipase A2 inhibitory proteins, which inhibit the release of arachidonic acid, thereby inhibiting the biosynthesis of potent mediators of inflammation, such as prostaglandins and leukotrienes. As a result, halobetasol reduces edema, erythema and pruritus through its cutaneous effects on vascular dilation and permeability. ( NCI )] (UMLS (NCI) C0098735) =Steroid; Pharmacologic Substance ;
=CLOBETASOL;
Halobetasol =Halobetasol;
HALOBETASOL PROPIONATE 0.05 % | - 84. Champus
- (UMLS (HL7) C0007938) =Health Care Related Organization =DRG Payor;
|
- 35. 21-Chloro-9-fluoro-11beta,16alpha,17-trihydroxypregn-4-ene-3,20-dione Cyclic 16,17-Acetal with Acetone
- [A topical, synthetic glucocorticoid with anti-inflammatory and anti-allergic properties. Halcinonide exerts its effect by interacting with specific intracellular receptors, and the ligand-receptor complex subsequently modulates gene expressions via the typical glucocorticoid signalling pathway. This results in the synthesis of certain anti-inflammatory proteins as well as in synthesis inhibition of certain inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions are accomplished. (NCI05) ( NCI )] (UMLS (NCI) C0018513) =Steroid; Pharmacologic Substance =Pregnenediones;
[DE200] ANTI-INFLAMMATORY, TOPICAL =HALCINONIDE 0.025 %;
HALCINONIDE 0.1 %;
| - 85. chancroid
- [Acute, localized autoinoculable infectious disease usually acquired through sexual contact. Caused by HAEMOPHILUS DUCREYI, it occurs endemically almost worldwide, especially in tropical and subtropical countries and more commonly in seaports and urban areas than in rural areas. ( MSH )] (UMLS (CSP) C0007947) =Disease or Syndrome =Haemophilus Infections;
Sexually Transmitted Diseases, Bacterial |
- 36. 3-Chloro-5-(3-(dimethylamino)propyl)-10,11-dihydro-5H-dibenz(b,f)azepine
- [A tricyclic antidepressant that acts by reducing the re-uptake of norepinephrine and serotonin in the central nervous system, thereby enhancing the effects of these neurotransmitters. This drug also binds to alpha-adrenergic, histaminergic, and cholinergic receptors which are responsible for the many side effects seen with this agent. ( NCI )] (UMLS (NCI) C0009010) =Organic Chemical; Pharmacologic Substance ;
=[CN601] TRICYCLIC ANTIDEPRESSANTS;
Dibenzazepines =3-Chloro-5-(3-(dimethylamino)propyl)-10,11-dihydro-5H-dibenz(b,f)azepine monohydrochloride;
| - 86. Chandipura virus
- [ ] (UMLS (CSP) C0318810) =Virus
|
- 37. 3-Chloro-5-(3-(dimethylamino)propyl)-10,11-dihydro-5H-dibenz(b,f)azepine monohydrochloride
- [The hydrochloride salt form of clomipramine, a tertiary amine salt derivative of dibenzazepine. Clomipramine hydrochloride is a tricyclic antidepressant that acts by reducing the re-uptake of norepinephrine and serotonin in the central nervous system, thereby enhancing the effects of these neurotransmitters. This drug also binds to alpha-adrenergic, histaminergic, and cholinergic receptors which are responsible for the many side effects seen with this agent. ( NCI )] (UMLS (NCI) C0282107) =Organic Chemical; Pharmacologic Substance ;
=3-Chloro-5-(3-(dimethylamino)propyl)-10,11-dihydro-5H-dibenz(b,f)azepine;
=CLOMIPRAMINE HYDROCHLORIDE 25 MG;
CLOMIPRAMINE HYDROCHLORIDE 50 MG;
CLOMIPRAMINE HYDROCHLORIDE 75 MG | - 87. Change
- [The act of alteration or modification; changed or altered in form or character. ( NCI )] (UMLS (NCI) C0392747) =Functional Concept
|
- 38. 3-Chloroprocainamide
- [A third-generation DNA repair inhibitor that modulates multi-drug resistance. ( NCI )] (UMLS (NCI) C0649622) =Organic Chemical
| - 88. Change file records as defined in the record-level event codes for each record that follows
- (UMLS (HL7) C1549600) =Intellectual Product =File level event code;
|
- 39. 4-(3Chloro-4-flurophenylamine)-7-methoxy-6(3-(4morpholinyl)quinazoline
- [A substance that is being studied as a treatment for cancer. It belongs to the family of drugs called epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors. Also called ZD 1839. ( NCI )] (UMLS (NCI) C1122962) 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-4-morpholin] propoxy];
Gefitinib;
GEFITINIB PREPARATION =Organic Chemical; Pharmacologic Substance ;
=[AN000] ANTINEOPLASTICS;
Unclassified Ingredients =GEFITINIB 250 MG | - 89. Change in abd size/distension
- (UMLS (ICPC) C0000731) (Change in abd size/distension; ABDOMENAREN BOLUMEN ALDAKETA/ABDOMEN HAUNDITZEA; AEndring af abdom omfang/udspiling; Verandering omvang/uitzetting buik; MAHAN TURVOTUS/KOON MUUTOS; Changement vol abdom/distension; Veraenderung des Bauchumfangs; (108); valtozas has mereteben/kitagulas; Cambiamenti vol addom/distensione; ENDR AV ABD-STORRELSE/UTSPILING; Alt volume abdominal/distensao; Cambios perimetro abd/distension; FORANDRING I BUKOMFANG) Change in abdominal size/distension =Finding ;
|
- 40. 4-Chloroamphetamine
- [Chlorinated analog of AMPHETAMINE. Potent neurotoxin that causes release and eventually depletion of serotonin in the CNS. It is used as a research tool. ( MSH )] (UMLS (NCI) C0030131) =Organic Chemical; Pharmacologic Substance ;
| - 90. Change in EKG
- [Changes in cardiac electrical activity. ( NCI )] (UMLS (NCI) C0855329) Changes in EKG/ECG;
ECG/EKG changes;
EKG/ECG Changes;
Electrocardiographic Change =Finding |
- 41. 4-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]-1-piperazineethanol
- [A phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties. Perphenazine blocks postsynaptic dopamine 2(D2) receptors in the mesolimbic and medullary chemoreceptor trigger zone (CTZ), thereby preventing the excess of dopamine in the brain. This leads to reduction in psychotic symptoms, such as hallucinations and delusions. Perphenazine appears to exert its antiemetic activity by blocking the dopamine and histamine-1 receptor in the CTZ thereby relieving nausea and vomiting in the brain. In addition, perphenazine binds to alpha-adrenergic receptors. ( NCI )] (UMLS (NCI) C0031184) =Organic Chemical; Pharmacologic Substance =Phenothiazine;
[CN701] PHENOTHIAZINES/RELATED, ANTIPSYCHOTICS =PERPHENAZINE 16 MG;
PERPHENAZINE 2 MG;
PERPHENAZINE 16 MG/5ML;
PERPHENAZINE 8 MG;
PERPHENAZINE 4 MG | - 91. Change in feces/bowel movements
- (UMLS (ICPC) C0497179) (Change in feces/bowel movements; DEFEKAZIO ERRITMO ALDAKETAK/BESTE MUGIMENDUAK; AEndring af afforing/affor vaner; Verandering ontlast/defec patr; MUUTOS ULOSTEESSA /SUOLEN TOIMINNASSA; Modific selles/mouvem intest; Veraenderung Stuhlgang/Darmtaetigkeit; shinui bayetziot; valtozas szekuritesben/belmozg.ban; Cambiamenti feci/movim intestinali; ENDRING I AVFORING/AVFORINGSVANE; Alt nas fezes/mov intestinais; Cambio en heces/ritmo intestinal; FORANDRING I AVFORING/AVFORINGSVANOR) =Sign or Symptom ;
=Body System, Gastrointestinal; Symptoms and Complaints Component |
- 42. 4-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)-1-butanone
- [USP lists as an antipsychotic and as an "antidyskinetic" used in Tourette syndrome. ( CSP )] (UMLS (NCI) C0018546) =Organic Chemical; Pharmacologic Substance =butyrophenone;
piperidine;
[CN700] ANTIPSYCHOTICS;
Dopamine Antagonist;
[CN709] ANTIPSYCHOTICS, OTHER;
=HALOPERIDOL DECANOATE;
HALOPERIDOL LACTATE;
HALOPERIDOL DECANOATE;
HALOPERIDOL LACTATE;
HALOPERIDOL 0.5 MG;
HALOPERIDOL 1 MG;
HALOPERIDOL 10 MG;
HALOPERIDOL 2 MG;
HALOPERIDOL 2 MG/ML;
HALOPERIDOL 20 MG;
HALOPERIDOL 5 MG;
HALOPERIDOL 5 MG/ML;
| - 92. Change in Voice
- (UMLS (NCI) C0518179) =Sign or Symptom
|
- 43. 5-Chloro-2,4-pyridinediol
- [A pyridine derivative with antitumor activity. Gimeracil enhances the antitumor activity of fluoropyrimidines by competitively and reversibly inhibiting the enzyme dihydropyrimidine dehydrogenase causing decreased degradation of the fluoropyrimidines. ( NCI )] (UMLS (NCI) C0535459) =Organic Chemical; Pharmacologic Substance
| - 93. Change order/service request
- (UMLS (HL7) C1548272) =Intellectual Product =Order control codes;
|
- 44. 5-Chloro-2-(6-methylpyridin-3-yl)-3-(4-methylsulfonylphenyl) Pyridine
- [A synthetic, nonsteroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic ,and potential antineoplastic properties. Etoricoxib specifically binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in inhibition of the conversion of arachidonic acid into prostaglandins. Inhibition of COX-2 may induce apoptosis and inhibit tumor cell proliferation and angiogenesis. ( NCI )] (UMLS (NCI) C0972314) Etoricoxib;
ETORICOXIB UNIDENTIFIED;
=Organic Chemical; Pharmacologic Substance ;
| - 94. Changed as requested
- (UMLS (HL7) C1548273) =Intellectual Product =Order control codes;
|
- 45. 51 chromium release assay
- [effector Cytotoxic T Lymphocytes (CTL) bind targets (infected cells) bearing virus peptide on syngeneic Class I MHC and signal the targets to undergo apoptosis; if the targets are labeled with 51Chromium before the CTL are added, the amount of 51Cr released into the supernatant is proportional to the number of targets killed. ( CSP )] (UMLS (CSP) C0201618) =Laboratory Procedure =immunologic assay;
| - 95. CHANGES IN SKIN TEXTURE
- [ ] (UMLS (ICD9CM) C0159040) =Sign or Symptom
|
- 46. 6-Chloro-2,3,4,5-tetrahydro-1-(p-hydroxyphenyl)-1H-3-benzazepine-7,8-diol methanesulfonate(salt)
- [The mesylate salt form of fenoldopam, a benzazepine derivative with rapid-acting vasodilator activity. Fenoldopam mesylate is a racemic mixture of S- and R- isomers; the latter is responsible for the biological activity and has a significantly higher affinity for dopamine D1-like receptors (D1 and D5) as well as moderate affinity to alpha2-adrenoceptors. This agent selectively activates the dopamine D1-like receptor, thereby causing vasodilatation and increasing renal perfusion. ( NCI )] (UMLS (NCI) C0700481) =Organic Chemical; Pharmacologic Substance =FENOLDOPAM;
=FENOLDOPAM MESYLATE 10 MG/ML;
| - 96. Changes in vascular appearance of retina
- (UMLS (ICD9CM) C1363843) RETINAL VASCULAR CHANGES;
=Disease or Syndrome ;
|
- 47. 6-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
- [The hydrogenated derivative of chlorothiazide, a thiazide diuretic with antihypertensive and anti-urolithic effects. This agent binds to the electroneutral Na-K-Cl cotransporter (NKCC) and thereby impairs Na+, K+ and Cl- reabsorption on the luminal membrane of the early segment in the distal convoluted tubule in the kidney. This leads to an increase in urinary excretion of sodium, chloride, potassium, bicarbonate and water subsequently reducing plasma and extracellular fluid volume leading to a reduction in blood pressure. Hydrochlorothiazide also decreases urinary calcium and uric acid excretion by direct action on the distal tubule. ( NCI )] (UMLS (NCI) C0020261) =Organic Chemical; Pharmacologic Substance ;
=chlorothiazide;
[CV701] THIAZIDES/RELATED DIURETICS =2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(dichloromethyl)-3,4-dihydro-, 1,1-Dioxide;
Hydrochlorothiazide 10 MG/ML;
HYDROCHLOROTHIAZIDE 100 MG;
HYDROCHLOROTHIAZIDE 12.5 MG;
HYDROCHLOROTHIAZIDE 15 MG;
HYDROCHLOROTHIAZIDE 25 MG;
HYDROCHLOROTHIAZIDE 30 MG;
HYDROCHLOROTHIAZIDE 50 MG;
HYDROCHLOROTHIAZIDE 6.25 MG;
HYDROCHLOROTHIAZIDE 125 MG;
HYDROCHLOROTHIAZIDE .25 MG | - 97. Changes of corneal membranes
- [ ] (UMLS (ICD9CM) C0155114) =Acquired Abnormality ;
|
- 48. 6-Chloro-9-((4-(diethylamino)-1-methylbutyl)amino)-2-methoxyacridine Dihydrochloride
- [The dihydrochloride salt of quinacrine, a 9-aminoacridine derivative, with potential antineoplastic property in addition to its antiparasitic activity. Quinacrine may exert its antineoplastic activity by inhibiting the transcription and activity of both basal and inducible nuclear factor-kappaB (NF-kappaB). Continuous NF-kappaB signaling, as present in many tumors as well as during chronic inflammation, promotes the expression of anti-apoptotic proteins and cytokines while suppressing the expression of pro-apoptotic proteins, such as p53, thereby inhibiting apoptosis and inducing proliferation. The repression of NF-kappaB by quinacrine leads to an induction of the transcription of the tumor suppressor p53. The activation of p53 restores p-53-dependent apoptotic pathways and potentially leads to an inhibition of tumor cell growth. ( NCI )] (UMLS (NCI) C0949411) Atabrine Dihydrochloride;
Mepacrine Dihydrochloride;
Quinacrine Dihydrochloride;
Quinacrine Hydrochloride;
SN 390 =Organic Chemical; Pharmacologic Substance | - 98. Changuinola virus
- [ ] (UMLS (CSP) C0007949) =Virus
|
- 49. 7-Chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one
- [benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action; its actions are mediated by enhancement of amma-aminobutyric acid activity; it is used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome. ( CSP )] (UMLS (NCI) C0012010) =Organic Chemical; Pharmacologic Substance =[CN400] ANTICONVULSANTS;
benzodiazepine;
Benzodiazepinones;
[CN300] SEDATIVES/HYPNOTICS;
[CN302] BENZODIAZEPINE DERIVATIVE, SEDATIVES/HYPNOTICS;
=DIAZEPAM 10 MG;
DIAZEPAM 15 MG;
DIAZEPAM 2 MG;
DIAZEPAM 5 MG/ML;
Diazepam 1 MG/ML;
DIAZEPAM 5 MG;
DIAZEPAM 2.5 MG;
DIAZEPAM 20 MG | - 99. Channel
- [A path through which water or other materials may flow or travel. ( NCI )] (UMLS (NCI) C0439799) =Spatial Concept
|
- 50. 7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-2-naphthacenecarboxamide
- [A semi-synthetic, broad-spectrum naphthacene antibiotic produced by the bacterium Streptomyces aureofaciens. Demeclocycline binds to bacterial 30S ribosomal subunit and prevents binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby inhibiting protein synthesis. Demeclocycline also inhibits the effect of vasopressin on the renal tubules, thereby causing diuresis. ( NCI )] (UMLS (NCI) C0011276) =Organic Chemical; Antibiotic =[AM250] TETRACYCLINES;
=7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-2-naphthacenecarboxamide Monohydrochloride;
| - 100. Channel calibration parameters
- (UMLS (HL7) C1547330) =Idea or Concept =Data type;
|
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