- 101. 2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine
- [antibacterial used in combination with a sulfonamide to treat some urinary tract infections and pneumocystis pneumonia, and alone as an antimalarial. ( CSP )] (UMLS (NCI) C0041041) =Organic Chemical; Pharmacologic Substance ;
=Pyrimidine;
antibacterial agent;
DAP;
[AM900] ANTI-INFECTIVES, OTHER =2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine Sulfate (2:1);
TRIMETHOPRIM 100 MG;
TRIMETHOPRIM 160 MG;
TRIMETHOPRIM 200 MG;
TRIMETHOPRIM 40 MG/5ML;
TRIMETHOPRIM 16 MG/ML;
TRIMETHOPRIM 80 MG;
TRIMETHOPRIM 50 MG/5ML;
| - 151. 3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolyl Penicillin Sodium Monohydrate
- [The sodium salt form of dicloxacillin, a broad-spectrum, semi-synthetic beta-lactam with bactericidal and beta-lactamase resistant activity. Dicloxacillin sodium binds to penicillin binding proteins (PBP) located on the inner membrane of the bacterial cell wall. It also inhibits the cross-linkage of peptidoglycan, a critical component of bacterial cell walls. This leads to the inhibition of bacterial cell wall synthesis and eventually causes cell lysis. ( NCI )] (UMLS (NCI) C0887422) DICLOXACILLIN SODIUM;
DICLOXACILLIN SODIUM PREPARATION =Organic Chemical; Antibiotic ;
=3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolylpenicillin;
=DICLOXACILLIN SODIUM 250 MG;
DICLOXACILLIN SODIUM 500 MG;
DICLOXACILLIN SODIUM 62.5 MG/5ML |
- 102. 2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine Sulfate (2:1)
- [The sulfate salt form of trimethoprim, a synthetic substituted pyrimidine with antibacterial activity. Trimethoprim sulfate selectively binds to and reversibly inhibits dihydrofolate reductase, thereby blocking the production of tetrahydrofolic acid from dihydrofolic acid. This leads to an inhibition of bacterial synthesis of folic acid, thereby affecting nucleic acid and protein synthesis. Trimethoprim sulfate has a stronger binding affinity for the bacterial enzyme than for the corresponding mammalian enzyme. ( NCI )] (UMLS (NCI) C0724713) Trimethoprim Sulfate;
TRIMETHOPRIM SULFATE PREPARATION;
=Organic Chemical; Pharmacologic Substance ;
=2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine;
=TRIMETHOPRIM SULFATE 0.1 % | - 152. 3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolylpenicillin
- [A broad-spectrum, semi-synthetic, beta-lactam, penicillin antibiotic with bactericidal and beta-lactamase resistant activity. Dicloxacillin binds to penicillin binding proteins (PBP) located on the inner membrane of the bacterial cell wall. It also inhibits the cross-linkage of peptidoglycan, a critical component of bacterial cell walls. This leads to the inhibition of bacterial cell wall synthesis and eventually causes cell lysis. ( NCI )] (UMLS (NCI) C0012093) =Organic Chemical; Antibiotic =CLOXACILLIN;
[AM053] PENICILLINASE-RESISTANT PENICILLINS =3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolyl Penicillin Sodium Monohydrate;
|
- 103. 2,4-Diamino-5-methyl-6-[(3,4,5-trimethoxyanilino)methyl]quinazoline mono-D-glucuronate
- [A drug that belongs to the family of drugs called antimetabolites. It is used in the treatment of pneumocystis carinii pneumonia and is being studied in the treatment of cancer. ( NCI )] (UMLS (NCI) C0077209) =Organic Chemical; Pharmacologic Substance ;
| - 153. 3-(2-Dimethylamino)ethylindol-4-ol Dihydrogen Phosphate
- [A tryptamine alkaloid, isolated from fungi of the genus Psilocybe with hallucinogenic, anxiolytic and psychoactive activities. Psilocybin is converted by phosphatases in vivo into the active compound psilocin. Psilocin exerts its effect by binding to and activating serotonin 2A (5-HT2A) and 1A (5-HT1A) receptors in the central nervous system, thereby mimicking the effects of serotonin. ( NCI )] (UMLS (NCI) C0033850) =Organic Chemical; Pharmacologic Substance
|
- 104. 2,4-Diamino-6-(2,5-dimethoxybenzyl)-5-methylpyrido[2,3-d]pyrimidine
- [An anticancer drug. ( NCI )] (UMLS (NCI) C0054332) =Organic Chemical; Pharmacologic Substance ;
| - 154. 3D image
- [ ] (UMLS (CSP) C1253948) three dimensional image =Manufactured Object
|
- 105. 2,4-Dichloro-1-(4-nitrophenoxy)benzene
- [A white, crystalline, solid, combustible, chlorinated compound. Nitrofen was used as an herbicide, but is no longer used or manufactured in the United States. Exposure to nitrofen irritates the skin, eyes and respiratory tract and affects the blood and central nervous system. This substance is teratogenic and carcinogenic in animals and is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0068833) =Organic Chemical; Hazardous or Poisonous Substance
| - 155. 3D imaging
- [Technique to produce 3D images to provide the ability to visualize important structures in great detail. Traditionally CT and MRI scans produced static output on film. To produce 3D images, many scans are made, and then combined by computers to produce a 3D model, which can then be manipulated by the physician. 3D ultrasounds are produced using a somewhat similar technique. ( NCI )] (UMLS (CSP) C0887832) 3-D Imaging;
Medical Imaging, Three Dimensional;
Three Dimensional Imaging =Diagnostic Procedure |
- 106. 2,4-dihydroxy-5-methylpyrimidine
- [2,4-diketo-5-methylpyrimidine; one of the 5 major bases (with adenine, guanine, cytosine, and uracil) found in nucleic acids. ( CSP )] (UMLS (NCI) C0040087) =Nucleic Acid, Nucleoside, or Nucleotide; Biologically Active Substance ;
=Pyrimidine;
nucleobase | - 156. 4',7-Dihydroxyisoflavone
- [An isoflavone extract from soy, which is an inactive analog of the tyrosine kinase inhibitor genistein. It has antioxidant and phytoestrogenic properties. (NCI) ( NCI )] (UMLS (NCI) C0057090) =Organic Chemical; Vitamin ;
|
- 107. 2,4-Dioxo-5-fluoropyrimidine
- [pyrimidine analog that is an antineoplastic antimetabolite. ( CSP )] (UMLS (NCI) C0016360) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
=[AN300] ANTINEOPLASTICS, ANTIMETABOLITES;
[AN000] ANTINEOPLASTICS;
2, 4-Dioxopyrimidine;
fluoropyrimidine;
uracil analog;
[DE600] ANTINEOPLASTICS, TOPICAL =FLUOROURACIL 50 MG/ML;
FLUOROURACIL 5 %;
FLUOROURACIL 1 %;
FLUOROURACIL 2 %;
FLUOROURACIL 0.5 %;
| - 157. 4,4'-(2,3-Dimethyl-1,4-butanediyl)bis[1,2-benzenediol]
- [A potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. The compound also inhibits formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase to a lesser extent. It also serves as an antioxidant in fats and oils. ( MSH )] (UMLS (NCI) C0028347) =Organic Chemical; Pharmacologic Substance ;
=catechol;
=MASOPROCOL;
|
- 108. 2,6 dimethoxyphenylpenicillin
- [semisynthetic penicillin used as an antibacterial in resistant staphylococcal infections. ( CSP )] (UMLS (CSP) C0025643) =Organic Chemical; Antibiotic ;
=Penicillanic Acid;
[AM050] PENICILLINS;
[AM053] PENICILLINASE-RESISTANT PENICILLINS;
=4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 6-((2,6-dimethoxybenzoyl)amino)-3,3-dimethyl-7-oxo-, Monosodium Salt, Monohydrate,(2S-(2alpha,5alpha,6beta))- | - 158. 4,4'-(Dimethylamino)benzophenone
- [A white to green colored leaflet material that emits toxic fumes of nitrogen oxides when heated to decomposition. Michler's ketone is used as a chemical intermediate in making dyes and pigments, particularly auramine derivatives, for dyeing paper, textiles, and leather. Exposure to Michler's ketone affects the central nervous system. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0066505) =Organic Chemical; Hazardous or Poisonous Substance
|
- 109. 2,6-Diamino-3-(phenylazo)-pyridine Hydrochloride
- [A synthetic, brick-red crystalline solid that is only slightly soluble in cold water and ethanol but is soluble in boiling water, acetic acid, glycerol, ethylene glycol and propylene glycol. It is used orally as a urinary tract analgesic. Side effects of phenazopyridine hydrochloride administration can include nausea, interference with the oxygen-carrying capacity of red blood cells (methemoglobinemia), hemolytic anemia as well as renal and hepatic toxicity. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0700555) =Organic Chemical; Pharmacologic Substance ;
=PHENAZOPYRIDINE;
=PHENAZOPYRIDINE HYDROCHLORIDE 100 MG;
PHENAZOPYRIDINE HYDROCHLORIDE 200 MG;
PHENAZOPYRIDINE HYDROCHLORIDE 50 MG;
PHENAZOPYRIDINE HYDROCHLORIDE 150 MG;
| - 159. 4,4'-Diaminodiphenylsulfide
- [A brown to violet colored solid aromatic amine that emits toxic fumes of nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen and sulfur oxides when heated to decomposition. 4,4'-Thiodianiline is primarily used as a chemical intermediate in the production of certain dyes. Exposure to this substance is irritating to the respiratory tract and can result in methemoglobinemia causing headache, dizziness, weakness and can lead to shortness of breath, collapse and even death. 4,4'-Thiodianiline is a possible mutagen and is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0047830) =Organic Chemical; Pharmacologic Substance ;
|
- 110. 2-((2,3-Dimethylphenyl)amino)benzoic Acid
- [An anthranilic acid and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activity. Mefenamic acid inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis, by prostaglandin synthase, is responsible for the therapeutic effects of mefenamic acid. Mefenamic acid also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation. ( NCI )] (UMLS (NCI) C0025152) =Organic Chemical; Pharmacologic Substance ;
=Anthranilic Acids;
[CN104] NONSTEROIDAL ANTI-INFLAMMATORY ANALGESICS =Mefenamate 250 MG | - 160. 4,4'-Diamonophenyl
- [A grayish-red, yellowish or white colored, very toxic, crystalline aromatic amine that darkens when exposed to air and light. Benzidine has been widely used for the detection of blood and as a reagent in the manufacture of dyes. Ingestion of benzidine causes cyanosis, headache, mental confusion, nausea and vomiting. Its use is now limited because of strong association between exposure to benzidine and an increased risk of bladder cancer in humans. (NCI05) ( NCI )] (UMLS (NCI) C0005047) =Organic Chemical; Hazardous or Poisonous Substance
|
- 111. 2-((2,6-Dichlorophenyl)amino)-benzeneacetic Acid, Monopotassium Salt
- [The potassium salt form of diclofenac, a benzene acetic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with analgesic, antipyretic and anti-inflammatory activity. Diclofenac potassium is a non-selective reversible and competitive inhibitor of cyclooxygenase (COX), subsequently blocking the conversion of arachidonic acid into prostaglandin precursors. This leads to an inhibition of the formation of prostaglandins that are involved in pain, inflammation and fever. ( NCI )] (UMLS (NCI) C0282131) =Organic Chemical; Pharmacologic Substance ;
=2-[(2,6-Dichlorophenyl)amino]benzeneacetic Acid;
2-[(2,6-Dichlorophenyl)amino]benzeneacetic Acid Monosodium Salt =DICLOFENAC POTASSIUM 50 MG | - 161. 4,4'-Dichloro-2,2'-methylenediphenol
- [A nontoxic laxative vermicide of chlorinated phenol compound. Dichlorophen is used as a veterinary fungicide, anthelmintic, and anti-protozoan, as well as an ingredient in antimicrobial soaps and shampoos. This agent probably acts by increasing the clearing of intestinal contents, thereby eradicating tapeworm infections from the intestines. ( NCI )] (UMLS (NCI) C0012082) =Organic Chemical; Pharmacologic Substance
|
- 112. 2-(2-(Diethylamino)ethoxy)-3-phenylpropiophenone
- (UMLS (NCI) C0059677) =Organic Chemical; Pharmacologic Substance ;
| - 162. 4,4'-Dichloro-3-(trifluoromethyl)-carbanilide
- [A synthetic, carbanilide compound with antiseptic activity. Cloflucarban is used as disinfectant and is found in antimicrobial soaps and deodorants. ( NCI )] (UMLS (NCI) C0055912) =Organic Chemical; Pharmacologic Substance ;
|
- 113. 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one
- [antioxidant flavonol widely distributed in plants. ( CSP )] (UMLS (NCI) C0034392) =Organic Chemical; Pharmacologic Substance; Vitamin =flavonoid;
vasoactive agent | - 163. 4,5-Diphenyl-2-oxazolepropionic Acid
- [A nonsteroidal anti-inflammatory drug (NSAID) derivative of oxazole-propionic acid with analgesic and antipyretic properties. As a first generation NSAID inhibitor, oxaprozin binds to and inactivates both isoforms of cyclooxygenase (COX-1 and-2), thereby blocking the conversion of arachidonic acid to pro-inflammatory prostaglandins. When inhibiting COX-2, this agent may be effective in relieving pain and inflammation; when inhibiting COX-1, it may produce unacceptable gastrointestinal side effects. (NCI04) ( NCI )] (UMLS (NCI) C0069739) =Organic Chemical; Pharmacologic Substance =Propionic Acids;
[MS102] NONSALICYLATE NSAIS, ANTIRHEUMATIC =OXAPROZIN 600 MG;
|
- 114. 2-(3,4-Dihydroxyphenyl)ethanol
- (UMLS (NCI) C0376776) =Organic Chemical; Pharmacologic Substance ;
| - 164. 4,9-Dimethoxy-7H-furo[3,2-g][1]benzopyran-7-one
- (UMLS (NCI) C0064041) =Organic Chemical
|
- 115. 2-(4-(((3,5-Dimethylanilino)Carbonyl)Methyl)Phenoxy)-2-Methylpropionic Acid
- [A synthetic small molecule with radiosensitizing activity. Efaproxiral increases oxygen levels in hypoxic tumor tissues by binding non-covalently to the hemoglobin tetramer and decreasing hemoglobin-oxygen binding affinity. Increasing tumor oxygenation reduces tumor radioresistance. (NCI04) ( NCI )] (UMLS (NCI) C0080719) =Organic Chemical; Pharmacologic Substance
| - 165. 4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl)benzenesulfornamide
- [A sulfonamide-derived, competitive and specific endothelin receptor antagonist with a slightly higher affinity for the endothelin A receptor than endothelin B receptor. Bosentan blocks the action of endothelin 1, an extremely potent endogenous vasoconstrictor and bronchoconstrictor, by binding to endothelin A and endothelin B receptors in the endothelium and vascular smooth muscle. Bosentan decreases both pulmonary and systemic vascular resistance and is particularly used in the treatment of pulmonary arterial hypertension. ( NCI )] (UMLS (NCI) C0252643) =Organic Chemical; Pharmacologic Substance =[CV900] CARDIOVASCULAR AGENTS, OTHER;
Unclassified Ingredients =BOSENTAN 125 MG;
BOSENTAN 62.5 MG;
|
- 116. 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide Monohydrochloride
- [The hydrochloride salt from of lidocaine, an aminoethylamide and a prototypical member of the amide class anesthetics. Lidocaine interacts with voltage-gated Na+ channels in the nerve cell membrane and blocks the transient increase in permeability of excitable membranes to Na+. This prevents the generation and conduction of nerve impulses and produces a reversible loss of sensation. Lidocaine hydrochloride also exhibits class IB antiarrhythmic effects. The agent decreases the flow of sodium ions into myocardial tissue, especially on the Purkinje network, during phase 0 of the action potential, thereby decreasing depolarization, automaticity and excitability. ( NCI )] (UMLS (NCI) C0546869) =Organic Chemical; Pharmacologic Substance =[CV300] ANTIARRHYTHMICS;
.omega.-Diethylamino-2,6-dimethylacetanilide;
[CN204] LOCAL ANESTHETICS, INJECTION;
[GU900] GENITOURINARY AGENTS, OTHER =LIDOCAINE HCL MISC. POWDER (GM);
LIDOCAINE HYDROCHLORIDE 1 %;
LIDOCAINE HYDROCHLORIDE 1 %WV;
LIDOCAINE HYDROCHLORIDE 100 MG/ML;
LIDOCAINE HYDROCHLORIDE 160 MG;
LIDOCAINE HYDROCHLORIDE 2.5 %;
LIDOCAINE HYDROCHLORIDE 300 MG;
LIDOCAINE HYDROCHLORIDE 4 %;
LIDOCAINE HYDROCHLORIDE 10 MG/ML;
LIDOCAINE HYDROCHLORIDE 0.5 %;
LIDOCAINE HYDROCHLORIDE 5 %;
LIDOCAINE HYDROCHLORIDE 1 GM;
LIDOCAINE HYDROCHLORIDE 200 MG/ML;
LIDOCAINE HYDROCHLORIDE 2 GM;
LIDOCAINE HYDROCHLORIDE 2 MG/ML;
LIDOCAINE HYDROCHLORIDE 4 MG/ML;
LIDOCAINE HYDROCHLORIDE 20 MG/ML;
LIDOCAINE HYDROCHLORIDE 1.5 %;
LIDOCAINE HYDROCHLORIDE 40 MG/ML;
LIDOCAINE HYDROCHLORIDE 8 MG/ML;
LIDOCAINE HYDROCHLORIDE 2 %;
| - 166. 4-(Dimethylamino)-1,4,4A,5,5A,6,11,12A-Octahydro-3,6,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-2-Naphthacenecarboxamide
- [A broad-spectrum naphthacene antibiotic produced semisynthetically from chlortetracycline, an antibiotic isolated from the bacterium Streptomyces aureofaciens. In bacteria, tetracycline binds to the 30S ribosomal subunit, interferes with the binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby inhibiting protein synthesis. ( NCI )] (UMLS (NCI) C0039644) =Organic Chemical; Antibiotic ;
=[GA303] H.PYLORI AGENTS;
[AM250] TETRACYCLINES =(4S,4aS,5aS,6S,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide Monohydrochloride;
TETRACYCLINE 125 MG/5ML;
TETRACYCLINE 500 MG |
- 117. 2-(DIETHYLAMINO)ETHANOL
- (UMLS (NCI) C0046079) =Organic Chemical; Pharmacologic Substance ;
| - 167. 4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolate
- [A tertiary amine possessing antimuscarinic and antispasmodic properties. Oxybutynin blocks muscarinic receptors in smooth muscle, hence inhibiting acetylcholine binding and subsequent reduction of involuntary muscle contractions. Oxybutynin is used to reduce bladder contractions by relaxing bladder smooth muscle. ( NCI )] (UMLS (NCI) C0069805) =Organic Chemical; Pharmacologic Substance ;
=Mandelic Acids;
[GU201] ANTISPASMODICS, URINARY =OXYBUTYNIN CHLORIDE;
OXYBUTYNIN 3.9 MG;
|
- 118. 2-(Diethylamino)ethyl 3-amino-4-propoxybenzoate Monohydrochloride
- [The hydrochloride salt form of proparacaine, a benzoic acid derivative with local anesthetic property. Proparacaine hydrochloride stabilizes the neuronal membrane by binding to and inhibiting voltage-gated sodium channels, thereby inhibiting sodium ion influx required for the initiation and conduction of impulses within the neuronal cell, and resulting in a loss of sensation. ( NCI )] (UMLS (NCI) C0740235) Benzoic Acid, 3-amino-4-propoxy-, 2-(diethylamino)ethyl Ester, Hydrochloride;
Proparacaine Hydrochloride;
PROPARACAINE HYDROCHLORIDE PREPARATION =Organic Chemical; Pharmacologic Substance =Proparacaine;
=PROPARACAINE HYDROCHLORIDE 0.5 % | - 168. 4-Dimethylaminoazobenzene
- [A yellow, crystalline solid compound. 4-Dimethylaminoazobenzene was used as a dye for coloring polishes, wax products, polystyrene and soap, and was also used as a pH indicator, but is no longer used or produced in the United States. Exposure to this substance causes dermatitis. 4-dimethylaminoazobenzene is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0012411) =Organic Chemical; Hazardous or Poisonous Substance ;
|
- 119. 2-(Diethylamino)ethyl p-aminobenzoate Monohydrochloride
- [The hydrochloride salt form of procaine, a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodium channels, thereby inhibiting the ionic flux required for the initiation and conduction of impulses. In addition, this agent increases electrical excitation threshold, reduces rate of rise of action potential and slows nerve impulse propagation thereby causing loss of sensation. ( NCI )] (UMLS (NCI) C0358490) =Organic Chemical; Pharmacologic Substance =PROCAINE;
=PROCAINE HYDROCHLORIDE 1 %;
PROCAINE HYDROCHLORIDE 2 %;
PROCAINE HYDROCHLORIDE 1.25 %;
PROCAINE HYDROCHLORIDE 10 %;
| - 169. 4-[2-[4-(3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-piperidinyl]-2-oxoethyl]-1-piperidinecarboxamide
- [A synthetic tricyclic derivative of carboxamide with antineoplastic properties. Lonarfanib binds to and inhibits farnesyl transferase, an enzyme involved in the post-translational modification and activation of Ras proteins. Ras proteins participate in numerous signalling pathways (proliferation, cytoskeletal organization), and play an important role in oncogenesis. Mutated ras proteins have been found in a wide range of human cancers. (NCI04) ( NCI )] (UMLS (NCI) C1257385) 4-[2-[4-[(11R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]-1-piperidinyl]-2-oxoethyl]-1-piperidinecarboxamide;
Lonafarnib;
=Organic Chemical; Pharmacologic Substance ;
|
- 120. 2-(Difluoromethyl)-DL-ornithine
- [polyamine antagonist which reversibly inhibits DNA polymerase and irreversibly inhibits ornithine decarboxylase; used against bladder cancer, with potential applications in epilepsy and PCP withdrawal. ( CSP )] (UMLS (NCI) C0086156) =Amino Acid, Peptide, or Protein; Pharmacologic Substance ;
=[AN000] ANTINEOPLASTICS;
Antiprotozoal Agent;
fluoroaminoacid;
| - 170. 5,5-Diphenyl-2,4-imidazolidinedione
- [anticonvulsant used in a wide variety of seizures; also an anti-arrhythmic and a muscle relaxant. ( CSP )] (UMLS (NCI) C0031507) =Organic Chemical; Pharmacologic Substance =[CN400] ANTICONVULSANTS;
hydantoin =5,5-Diphenyl-2,4-imidazolidinedione, Monosodium Salt;
Fosphenytoin;
PHENYTOIN SODIUM EXTENDED;
5,5-Diphenyl-2,4-imidazolidinedione, Monosodium Salt;
PHENYTOIN SODIUM EXTENDED;
PHENYTOIN 125 MG/5ML;
PHENYTOIN 50 MG;
PHENYTOIN 30 MG/5ML;
PHENYTOIN 100 MG |
- 121. 2-(Difluoromethyl)-dl-ornithine Hydrochloride, Monohydrate
- [The hydrochloride form of eflornithine, a difluoromethylated ornithine compound with antineoplastic activity. Eflornithine irreversibly inhibits ornithine decarboxylase, an enzyme required for polyamine biosynthesis, thereby inhibiting the formation and proliferation of tumor cells. Polyamines are involved in nucleosome oligomerization and DNA conformation, creating a chromatin environment that stimulates neoplastic transformation of cells. (NCI04) ( NCI )] (UMLS (NCI) C0282042) =Amino Acid, Peptide, or Protein; Pharmacologic Substance =Alpha-Difluoromethylornithine;
=EFLORNITHINE HYDROCHLORIDE 13.9 % | - 171. 5,5-Diphenyl-2,4-imidazolidinedione, Monosodium Salt
- [The sodium salt form of phenytoin, a hydantoin derivate and non-sedative antiepileptic agent with anticonvulsant activity. Phenytoin sodium promotes sodium efflux from neurons located in the motor cortex, thereby stabilizing the neuron and inhibiting synaptic transmission. This leads to a reduction in posttetanic potentiation at synapses, an inhibition of repetitive firing of action potentials and ultimately inhibits the spread of seizure activity. ( NCI )] (UMLS (NCI) C0237417) =Organic Chemical; Pharmacologic Substance =5,5-Diphenyl-2,4-imidazolidinedione;
=PHENYTOIN SODIUM 100 MG;
PHENYTOIN SODIUM 125 MG/5ML;
PHENYTOIN SODIUM 50 MG/ML;
PHENYTOIN SODIUM 30 MG;
PHENYTOIN SODIUM 300 MG;
PHENYTOIN SODIUM 200 MG;
|
- 122. 2-Diethylaminoethyl 4-amino-2-chlorobenzoate Hydrochloride
- [A synthetic, aminoester, local, anesthetic agent. At the injection site, chloroprocaine hydrochloride acts by inhibiting sodium influx through binding to specific membrane sodium ion channels in the neuronal cell membranes, restricting sodium permeability, and blocking nerve impulse conduction. This leads to a loss of sensation. Chloroprocaine hydrochloride is short-acting due to rapid hydrolysis by pseudocholinesterase into para-aminobenzoic acid in plasma. ( NCI )] (UMLS (NCI) C0132182) =Organic Chemical; Pharmacologic Substance ;
=chloroprocaine;
=CHLOROPROCAINE HYDROCHLORIDE 2 %;
CHLOROPROCAINE HYDROCHLORIDE 1 %;
CHLOROPROCAINE HYDROCHLORIDE 3 %;
| - 172. 5,6-Dimethylxanthenone-4-Acetic Acid
- [An anticancer drug that belongs to the family of drugs called angiogenesis inhibitors. ( NCI )] (UMLS (NCI) C0081181) =Organic Chemical; Pharmacologic Substance
|
- 123. 2-[(2,6-Dichlorophenyl)amino]benzeneacetic Acid
- [A nonsteroidal benzeneacetic acid derivative with anti-inflammatory activity. As a nonsteroidal anti-inflammatory drug (NSAID), diclofenac binds and chelates both isoforms of cyclooxygenase (COX-1 and-2), thereby blocking the conversion of arachidonic acid to pro-inflammatory-proprostaglandins. This agent also may inhibit COX-2-mediated tumor angiogenesis. When inhibiting COX-2, diclofenac may be effective in relieving pain and inflammation; when inhibiting COX-1, it may produce unacceptable gastrointestinal side effects. This agent may be more active against COX-2 than several other carboxylic acid-containing NSAIDs. (NCI04) ( NCI )] (UMLS (NCI) C0012091) =Organic Chemical; Pharmacologic Substance =phenylacetate;
[MS102] NONSALICYLATE NSAIS, ANTIRHEUMATIC;
[OP300] ANTI-INFLAMMATORIES, TOPICAL OPHTHALMIC;
=2-[(2,6-Dichlorophenyl)amino]benzeneacetic Acid Monosodium Salt;
2-((2,6-Dichlorophenyl)amino)-benzeneacetic Acid, Monopotassium Salt;
2-[(2,6-Dichlorophenyl)amino]benzeneacetic Acid Monosodium Salt;
| - 173. 5,7-Dichloro-8-hydroxyquinoline
- [A synthetic quinoline derivative with antibacterial activity. Although the mechanism of action is not fully understood, topical administration of chloroxine diminishes mitotic activity in the epidermis, thereby reducing excessive scaling associated with dandruff or seborrheic dermatitis of the scalp, including psoriasis and eczema. ( NCI )] (UMLS (NCI) C0055461) =Organic Chemical; Pharmacologic Substance =Chloroquinolinols;
[DE400] SOAPS/SHAMPOOS/SOAP-FREE CLEANSERS =CHLOROXINE 2 % |
- 124. 2-[(2,6-Dichlorophenyl)amino]benzeneacetic Acid Monosodium Salt
- [The sodium salt form of diclofenac, a benzene acetic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with analgesic, antipyretic and anti-inflammatory activity. Diclofenac sodium is a non-selective reversible and competitive inhibitor of cyclooxygenase (COX), subsequently blocking the conversion of arachidonic acid into prostaglandin precursors. This leads to an inhibition of the formation of prostaglandins that are involved in pain, inflammation and fever. ( NCI )] (UMLS (NCI) C0700583) =Organic Chemical; Pharmacologic Substance =2-[(2,6-Dichlorophenyl)amino]benzeneacetic Acid;
=2-((2,6-Dichlorophenyl)amino)-benzeneacetic Acid, Monopotassium Salt;
DICLOFENAC SODIUM 0.1 %;
DICLOFENAC SODIUM 50 MG;
DICLOFENAC SODIUM 75 MG;
DICLOFENAC SODIUM 100 MG;
DICLOFENAC SODIUM 25 MG;
DICLOFENAC SODIUM 3 % | - 174. 5-(((2,5-Dihydroxyphenyl)methyl)((2-hydroxyphenyl)methyl)amino)-2-hydroxy Benzoic Acid
- [A compound isolated from strains of Streptomyces griseolavendus that may exert antitumor activity by inhibition of protein tyrosine kinase and tubulin polymerization. (NCI) ( NCI )] (UMLS (NCI) C0064695) =Organic Chemical; Pharmacologic Substance ;
|
- 125. 2-[3-(Dimethyl-amino)propyl]-8,8-diethyl-2-aza-8-germaspiro[4,5]decane
- [A synthetic organometallic compound containing the element germanium with possible antineoplastic activity. Spirogermanium exhibits significant toxicity, particularly neurotoxicity. (NCI04) ( NCI )] (UMLS (NCI) C0075018) =Organic Chemical; Pharmacologic Substance ;
| - 175. 5-((3,5-dibutyl-1H-1,2,4-triazol-1-yl)methyl)-2-(2-(1H-tetrazol-5-yl)phenyl)pyridine
- [A nonpeptide angiotensin II receptor antagonist with antihypertensive activity. Forasartan selectively competes with angiotensin II for the binding of the angiotensin II (AT1) receptor subtype 1 in vascular smooth muscle, thereby blocking angiotensin II-mediated vasoconstriction resulting in vascular dilatation. In addition, the antagonistic effect on AT1 in the adrenal gland, prevents angiotensin II-induced stimulation of aldosterone synthesis and secretion by the adrenal cortex. This blocks the effects of aldosterone leading to an increase in sodium excretion and water and eventually a reduction in plasma volume and blood pressure. ( NCI )] (UMLS (NCI) C0250070) =Organic Chemical; Pharmacologic Substance ;
|
- 126. 3', 5'-Dichloroamethopterin
- [A chlorinated methotrexate derivative. Dichloromethotrexate inhibits the enzyme dihydrofolate reductase, thereby preventing the synthesis of purine nucleotides and thymidylates and inhibiting DNA and RNA synthesis. This agent is metabolized and excreted by the liver. (NCI04) ( NCI )] (UMLS (NCI) C0046764) =Organic Chemical; Pharmacologic Substance
| - 176. 5-(1,2-Dithiolan-3-yl)pentanoic Acid
- [A naturally occurring micronutrient, synthesized in small amounts by plants and animals (including humans), with potential chemopreventive and protective properties. Alpha-lipoic acid acts as a free radical scavenger and assists in repairing oxidative damage, regenerates endogenous antioxidants, including vitamin C, E and glutathione. This antioxidant also promotes glutathione synthesis. In addition, alpha-lipoic acid exerts metal chelating capacities and functions as a cofactor in various mitochondrial enzyme complexes involved in the decarboxylation of alpha-keto acids. ( NCI )] (UMLS (NCI) C0023791) =Organic Chemical; Pharmacologic Substance; Vitamin
|
- 127. 3',4'-Didehydro-4'-deoxy-C'-norvincaleukoblastine
- [An anticancer drug that belongs to the family of plant drugs called vinca alkaloids. ( NCI )] (UMLS (NCI) C0078257) =Organic Chemical; Pharmacologic Substance ;
=[AN000] ANTINEOPLASTICS;
VINBLASTINE =NVB | - 177. 5-[[4-[4(3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy]phenyl]methyl\-2,4-thiazolidinedione
- [A drug used in diabetes treatment that is being studied for its effect on reducing the risk of cancer cell growth in fat tissue. ( NCI )] (UMLS (NCI) C0245514) =Organic Chemical; Pharmacologic Substance ;
=Chromans;
antihyperglycemic;
thiazole;
Unclassified Ingredient Preparations |
- 128. 3,12-Diaza-6,9-diazoniadispiro(5.2.5.2)hexadecane, 3,12-bis(3-chloro-2-hydroxypropyl)-, dichloride
- [An dispiropiperazine derivative with potential cytostatic, anti-inflammatory and immune-suppressive properties. Although the exact mechanism of action of prospidin is not known, this agent was shown to interact with DNA, disrupting cell cycle at G2 phase, inhibiting phagocytic activity of monocytes and macrophage. Prospidin has good anti-lupus activity due to its immunosuppressive effects and was also used in refractory rheumatoid arthritis as an anti-rheumatic drug. (NCI04) ( NCI )] (UMLS (NCI) C0033524) =Organic Chemical; Pharmacologic Substance
| - 178. 6-(2,2-Dimethyl-5-oxo-4-phenyl-1-imidazolidinyl)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid
- [A semi-synthetic penicillin compound with bactericidal properties. Hetacillin is a prodrug that is converted to ampicillin. Ampicillin binds to inactivated penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs, including transpeptidases, carboxypeptidases, and endopeptidases, participate in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. This results in the weakening of the bacterial cell wall and eventually causes cell lysis. (NCI05) ( NCI )] (UMLS (NCI) C0062587) =Organic Chemical; Antibiotic ;
|
- 129. 3,3'-Diindolymethane
- [A phytonutrient and plant indole found in cruciferous vegetables including broccoli, Brussels sprouts, cabbage, cauliflower and kale, with potential anti-androgenic and antineoplastic activities. As a dimer of indole-3-carbinol, diindolylmethane (DIM) promotes beneficial estrogen metabolism in both sexes by reducing the levels of 16-hydroxy estrogen metabolites and increasing the formation of 2-hydroxy estrogen metabolites, resulting in increased antioxidant activity. Although this agent induces apoptosis in tumor cells in vitro, the exact mechanism by which DIM exhibits its antineoplastic activity in vivo is unknown. ( NCI )] (UMLS (NCI) C1100708) 3,3'-Methylenebis-1H-indole;
CCRIS 5806;
Diindolylmethane;
=Organic Chemical; Pharmacologic Substance ;
| - 179. 6-DIAZO-5-OXO-L-NORLEUCINE
- [An antibiotic isolated from Streptomyces with potential antineoplastic activity. Diazooxonorleucine inhibits several glutamine-dependent biosynthetic pathways including the synthesis of D-glucosamine phosphate, purines and pyrimidines. As an L-glutamine antagonist, diazooxonorleucine inhibits phosphate-activated glutaminase, thereby interfering with glutamine metabolism, ultimately depleting cells of this essential amino acid and reducing the capacity to proliferate. Another mechanism of action including inhibition of glycoprotein, gamma-guanosine triphosphatease, DNA and RNA synthesis has been proposed. ( NCI )] (UMLS (NCI) C0012020) =Amino Acid, Peptide, or Protein; Pharmacologic Substance
|
- 130. 3,3'-Dimethoxybenzidine
- [A colorless, highly toxic, crystalline compound that turns violet when exposed to air. Dianisidine is used exclusively as an intermediate for the production of dyes and pigments. Exposure to this substance causes skin irritation and sensitization. Dianisidine is reasonably anticipated to be a human carcinogen based on evidence of carcinogenicity in experimental animals. (NCI05) ( NCI )] (UMLS (NCI) C0011969) =Organic Chemical; Hazardous or Poisonous Substance ;
| - 180. 6-Dibromodideoxydulcitol
- [An anticancer drug that belongs to the family of drugs called alkylating agents. ( NCI )] (UMLS (NCI) C0026252) =Carbohydrate; Pharmacologic Substance ;
|
- 131. 3,3'-Dimethyl-4,4'-biphenyldiamine
- [A white to reddish colored, combustible, aromatic amine that emits toxic fumes of nitrogen oxides when heated to decomposition. o-Tolidine is used in industry as a dye or as an intermediate in the manufacture of dyes and pigments and is also used in clinical laboratories for the detection of blood. Exposure to this substance irritates the eyes, skin and respiratory tract and damages the kidneys and liver. o-Tolidine is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0046581) =Organic Chemical; Hazardous or Poisonous Substance
| - 181. 6-[(3,4-dihydro-4,4-dimethyl-2H-1-benzothiopyran-6-yl)ethynyl]- 3-Pyridinecarboxylic Acid, Ethyl Ester
- [A synthetic, topical retinoid. Tazarotene induces the expression of tazarotene-induced gene 3 (TIG3), a tumor suppressor gene. In psoriasis, tazarotene normalizes abnormal keratinocyte differentiation and reduces their hyperproliferation. (NCI04) ( NCI )] (UMLS (NCI) C0288792) =Organic Chemical; Pharmacologic Substance ;
=Nicotinic Acids;
[DE752] ANTIACNE AGENTS, TOPICAL =TAZAROTENE 0.1 %;
TAZAROTENE 0.05 % |
- 132. 3,3-Dichloro-(1,1-Biphenyl)-4,4-Diamine
- [A synthetic, light-sensitive, gray to purple crystalline solid that is insoluble in cold water but is soluble in ether, benzene, glacial acetic acid and alcohol. It is used primarily in the manufacture of pigments for printing ink, textiles, paper, paint, rubber, and plastics and as a curing agent for isocyanate-containing polymers and solid urethane plastics. When heated to decomposition, 3,3-dichlorobenzidine emits toxic fumes of chlorinated compounds and nitrogen oxides. The primary routes of potential human exposure to 3,3-dichlorobenzidine are inhalation of airborne dust, ingestion of contaminated well water by those living near hazardous waste sites, and dermal contact, primarily during industrial operations. Contact with this compound may cause dermatitis. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0000370) =Organic Chemical; Hazardous or Poisonous Substance ;
| - 182. 7,8-Didehydro-4,5-epoxy- 3-methoxy-17-methyl-(5a ,6a)-Morphinan-6-ol Sulfate (2:1)
- [The sulfate salt form of codeine, a naturally occurring phenanthrene alkaloid and opioid agonist with analgesic, antidiarrheal and antitussive activity. Codeine sulfate mimics the actions of opioids by binding to the opioid receptors at many sites within the central nervous system (CNS). Stimulation of the mu-subtype opioid receptor stimulates the exchange of GTP for GDP on the G-protein complex and subsequently inhibits adenylate cyclase. This results in a decrease in intracellular cAMP and leads to a reduction in the release of neurotransmitters such as substance P, GABA, dopamine, acetylcholine and noradrenaline. The analgesic effect of codeine sulfate is likely due to its metabolite morphine, which induces opening of G-protein-coupled inwardly rectifying potassium (GIRK) channels and blocks the opening of N-type voltage-gated calcium channels, thereby resulting in hyperpolarization and reduced neuronal excitability. ( NCI )] (UMLS (NCI) C0304352) =Organic Chemical; Pharmacologic Substance =codeine;
=CODEINE SULFATE 10 MG;
CODEINE SULFATE 30 MG;
CODEINE SULFATE 10 MG/5ML;
CODEINE SULFATE 60 MG;
CODEINE SULFATE 15 MG |
- 133. 3,4 dihydroxyphenylacetate
- [metabolite of DOPA. ( CSP )] (UMLS (CSP) C0178432) =Organic Chemical ;
=phenylacetate;
| - 183. 7,8-Dihydro-8-Oxoguanine Triphosphatase
- [Human 7,8-dihydro-8-oxoguanine triphosphatase protein (197 aa, 23 kD - unprocessed precursor) is encoded by the nudix (nucleoside diphosphate linked moiety X)-type motif 1 gene (NUDT1). Isoforms of this soluble protein are localized to both the cytoplasm and mitochondria of the cell. It catalyzes the hydrolysis of 8-oxo-dGTP to yield 8-oxo-dGMP and diphosphate. Misincorporation of 8-oxo-dGTP into DNA can result in A:T to C:G transversion mutations. Therefore, this enzyme is considered to be antimutagenic. ( NCI )] (UMLS (NCI) C0210507) =Amino Acid, Peptide, or Protein; Enzyme ;
|
- 134. 3,4,5,6-Dibenzocarbazole
- [A crystalline, carcinogenic aromatic hydrocarbon consisting of five fused rings and produced during the incomplete combustion of organic matter. 7H-Dibenzo[c,g]carbazole is primarily found in cigarette tar. This substance is used only for research purposes. 7H-Dibenzo[c,g]carbazole is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0049973) =Organic Chemical; Hazardous or Poisonous Substance
| - 184. 9,10-Dihydroergotamine Mesylate
- [An ergot derivative with agonistic activity for alpha-adrenergic, serotonergic, and dopaminergic receptors. Dihydroergotamine mesylate most likely relieves migraine headaches by binding to and stimulating the 5-HT1D receptor subtype, thereby causing constriction of cerebral blood vessels. However, it has also been proposed that dihydroergotamine mesylate acts upon 5-HT1D receptors on sensory nerve endings of the trigeminal system, thereby decreasing the release of pro-inflammatory neuropeptide release. ( NCI )] (UMLS (NCI) C0700532) =Organic Chemical; Pharmacologic Substance =DIHYDROERGOTAMINE;
=DIHYDROERGOTAMINE MESYLATE 1 MG/ML;
DIHYDROERGOTAMINE MESYLATE 4 MG/ML;
|
- 135. 3,4-Dihydro-2,2-dimethyl-2H-naphtho(1,2-b)pyran-5,6-dione
- [A naphthoquinone compound derived from bark of Tabebuia sp., with antitumor, antibacterial, antifungal and antitrypanosomal activities. Beta-lapachone exerts its anti-tumor effect by indirect actions of inducing p53-independent apoptosis and cell cycle arrest mediated through altered activities of cell cycle control regulatory proteins; including down-regulating retinoblastoma protein (pRB), a transcriptional repressor target at transcription factor E2F-1, as well as induces expression of cyclin dependent kinase inhibitor 1A (CDKN1A or p21). Both E2F-1 and p21 are required for G1/S-phase transition during cell cycle. This agent also inhibits DNA topoisomerase I by a mechanism distinct from that of camptothecin, and thereby blocks the formation of a cleavable complex leading to enzyme inhibition and prevent DNA repair. Furthermore, beta-lapachone could induce reactive oxygen species in vivo, and result in cytotoxicity. ( NCI )] (UMLS (NCI) C0053471) =Organic Chemical; Pharmacologic Substance ;
| - 185. Di-Adreson-F
- (UMLS (NCI) C0699539) =Steroid; Pharmacologic Substance
|
- 136. 3,4-Dihydro-2-amino-6-methyl-4-oxy-5-(4-pyridylthio)-quinazoline Dihydrochloride
- [The hydrochloride salt form of nolatrexed, a water-soluble lipophilic quinazoline folate analog with antineoplastic activity. Nolatrexed occupies the folate binding site of thymidylate synthase, resulting in inhibition of thymidylate synthase activity and thymine nucleotide synthesis with subsequent inhibition of DNA replication, DNA damage, S-phase cell cycle arrest, and caspase-dependent apoptosis. This agent also exhibits radiosensitizing activity. (NCI04) ( NCI )] (UMLS (NCI) C0389037) =Organic Chemical; Pharmacologic Substance
| - 186. Di-dgA-RFB4 Immunotoxin
- [An anticancer drug that is a combination of a monoclonal antibody (RFB4) and an immunotoxin (dgA). ( NCI )] (UMLS (NCI) C0677768) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor
|
- 137. 3,4-dihydro-3-methyl-4-oxoimidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide
- [dacarbazine derivative; alkylating antineoplastic agent. ( CSP )] (UMLS (NCI) C0076080) =Organic Chemical; Pharmacologic Substance =[AN000] ANTINEOPLASTICS;
1H-imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazenyl)-;
Antineoplastic Alkylating Agent;
=TEMOZOLOMIDE 20 MG;
TEMOZOLOMIDE 100 MG;
TEMOZOLOMIDE 5 MG;
TEMOZOLOMIDE 250 MG;
| - 187. DIA (differentiation inhibiting activity)
- [ ] (UMLS (CSP) C0113865) =Amino Acid, Peptide, or Protein; Immunologic Factor
|
- 138. 3,4-dihydroxy-4'-methyl-5-nitrobenzophenone
- [A benzophenone derivative and a catechol-O-methyltransferase (COMT) inhibitor. Tolcapone selectively and reversibly inhibits COMT, an enzyme that catalyzes the metabolism of biologically active catechols and their hydroxylated metabolites by transferring the methyl group of S-adenosyl-L-methionine to the phenolic group of catechol-containing substrates. When given in conjunction with a peripheral dopa decarboxylase inhibitor and levodopa, tolcapone may prevent the metabolism of levodopa to 3-methoxy-4-hydroxy- L-phenylalanine (3-OMD) in the brain and peripheral tissues leading to increased bioavailability and enhancement of delivery to the central nervous system (CNS) of levodopa. ( NCI )] (UMLS (NCI) C0246330) =Organic Chemical; Pharmacologic Substance ;
=[CN500] ANTIPARKINSON AGENTS;
Benzophenones =TOLCAPONE 100 MG;
TOLCAPONE 200 MG;
| - 188. diabetes amputation
- [ ] (UMLS (CSP) C0598284) =Therapeutic or Preventive Procedure
|
- 139. 3,4-Dihydroxybenzohydroxamic acid
- [3,4-dihydroxybenzohydroxamic acid. An inhibitor of ribonucleotide reductase. ( NCI )] (UMLS (NCI) C0094556) =Organic Chemical; Pharmacologic Substance ;
| - 189. diabetes bronze
- [condition in which there is a deviation or interruption in the storage of iron in the body. ( CSP )] (UMLS (CSP) C0018995) =Disease or Syndrome =DIS IRON METABOLISM;
inborn metal metabolism disorder;
iron overload;
=hemosiderosis;
|
- 140. 3,4-Dihydroxyphenylethanol
- (UMLS (NCI) C0046981) =Organic Chemical; Pharmacologic Substance
| - 190. diabetes education
- [instruction or training that encourages behaviors most likely to optimize health potentials through information about diabetes; facilitates the prevention of diabetes, frequently for those who are at risk for developing diabetes; also includes instruction or training that increases the awareness and favorably influences the attitudes and knowledge about diabetes on a personal or community basis; it also includes the training of medical personnel about diabetes for prevention or treatment programs, for this type of diabetes education postcoordinate with the appropriate health professional education term. ( CSP )] (UMLS (CSP) C0850356) =Educational Activity =health education;
|
- 141. 3,5-Diacetamido-2,4,6-triiodobenzoic Acid, Sodium Salt
- [An iodinated radiopaque X-ray contrast medium. Diatrizoate sodium blocks X-rays, thereby allowing body structures containing iodine to be delineated in contrast to those structures that do not contain iodine and allowing visualization of these areas. This contrast agent is used as a diagnostic aid in angiography, urography and radiography. (NCI05) ( NCI )] (UMLS (NCI) C0012007) =Organic Chemical; Indicator, Reagent, or Diagnostic Aid =3,5-Bis(acetylamino)-2,4,6-triiodobenzoic Acid;
1-Deoxy-1-(methylamino)-D-glucitol 3,5-diacetamido-2,4,6-triiodobenzoate (salt) =DIATRIZOATE NA PWDR,ORAL;
DIATRIZOATE SODIUM 80 MG/ML;
DIATRIZOATE SODIUM 100 MG;
DIATRIZOATE SODIUM 8 %;
DIATRIZOATE SODIUM 20 %;
DIATRIZOATE SODIUM 35 %;
DIATRIZOATE SODIUM 50 %;
DIATRIZOATE SODIUM 42 %;
DIATRIZOATE SODIUM 25 %;
DIATRIZOATE SODIUM 10 %;
DIATRIZOATE SODIUM 30 %;
DIATRIZOATE SODIUM 29.1 % | - 191. Diabetes Educator
- (UMLS (HL7) C1555973) =Intellectual Product =Registered Nurse;
|
- 142. 3,5-Dibromo-N-(4-bromophenyl)-2-hydroxybenzamide
- [A salicylanilide derivative with antibacterial and antifungal activities banned by FDA due to its photosensitizing effect. Tribromsalan is used as disinfectant in medicated soaps. ( NCI )] (UMLS (NCI) C0077019) =Organic Chemical; Pharmacologic Substance ;
| - 192. DIABETES IN PREG-UNSPEC
- [ ] (UMLS (ICD9CM) C0341893) =Disease or Syndrome
|
- 143. 3,5-dichloro-2,4-dimethoxy-6-(trichloromethyl) pyridine
- [An anticancer drug that belongs to the family of drugs called alkylating agents. ( NCI )] (UMLS (NCI) C0070220) =Organic Chemical; Pharmacologic Substance
| - 193. Diabetes in Pregnancy
- [glucose intolerance which onsets during pregnancy; does not include diabetics who become pregnant or women who become lactosuric; after pregnancy, the woman is reclassified as diabetic or not depending on whether glucose intolerance persists. ( CSP )] (UMLS (NCI) C0085207) =Disease or Syndrome ;
=Diabete mellito;
Pregnancy Complication;
Pregnancy Disorder;
=fetal macrosomia |
- 144. 3,6-Dinitro-2-phenyl-4H-1-benzopyran-4-one
- (UMLS (NCI) C0538186) =Organic Chemical; Pharmacologic Substance ;
| - 194. diabetes insipidus
- [metabolic disorder due to injury of the neurohypophyseal system; results in deficient quanity of antidiuretic hormone being released or produced, failure of tubular reabsorption of water in the kidney. ( CSP )] (UMLS (CSP) C0011848) =Disease or Syndrome =hypopituitarism;
Metabolic Disease =Diabetes Insipidus, Nephrogenic;
Wolfram syndrome;
Diabetes Insipidus, Nephrogenic;
antidiuretic hormone defective syndrome |
- 145. 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione
- [1,3-dimethylxanthine; methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. ( CSP )] (UMLS (NCI) C0039771) =Organic Chemical; Pharmacologic Substance; Biologically Active Substance =bronchodilator;
Xanthine Alkaloids;
xanthine;
Muscle Relaxant;
methylpurine;
[RE104] BRONCHODILATORS, XANTHINE-DERIVATIVE =1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-, compound with 1,2-Ethanediamine(2:1);
DIMENHYDRINATE;
1H-Purine-2,6-dione, 7-(2,3-dihydroxypropyl)-3,7-dihydro-1,3-dimethyl;
Choline, hydroxide, compound with Theophylline(1:1);
pamabrom;
Theophylline Anhydrous;
THEOPHYLLINE CALCIUM SALICYLATE;
THEOPHYLLINE SODIUM GLYCINATE;
THEOPHYLLINE CALCIUM SALICYLATE;
THEOPHYLLINE SODIUM GLYCINATE;
THEOPHYLLINE 0.4 MG/ML;
THEOPHYLLINE 0.8 MG/ML;
Theophylline 10 MG/ML;
THEOPHYLLINE 100 MG;
THEOPHYLLINE 120 MG;
THEOPHYLLINE 125 MG;
THEOPHYLLINE 2 MG/ML;
THEOPHYLLINE 250 MG;
THEOPHYLLINE 3.2 MG/ML;
THEOPHYLLINE 300 MG;
THEOPHYLLINE 4 MG/ML;
THEOPHYLLINE 450 MG;
THEOPHYLLINE 600 MG;
THEOPHYLLINE 1.6 MG/ML;
THEOPHYLLINE 200 MG;
THEOPHYLLINE 400 MG;
THEOPHYLLINE 100 MG/18.75ML;
THEOPHYLLINE 100 MG/15ML;
Theophylline 10.7 MG/ML;
Theophylline 5.9 MG/ML;
THEOPHYLLINE SODIUMGLYCINATE;
THEOPHYLLINE 80 MG/15ML;
| - 195. Diabetes mellitus
- [heterogeneous group of disorders that share glucose intolerance in common.(CSP)] (UMLS (ICPC) C0011849) (Diabetes mellitus; DIABETES MELITUSA; Diabetes mellitus; Diabetes mellitus; SOKERITAUTI; Diabete sucre; Diabetes mellitus; sukeret; diabetes mellitus; Diabete mellito; SUKKERSYKE/DIABETES MELLITUS; Diabetes mellitus; Diabetes mellitus; DIABETES MELLITUS/SOCKERSJUKA) =Disease or Syndrome =Endocrine Disease; Metabolic Disease; Endocrine Pancreas Disease; ENDOCRINE, METABOLIC AND NUTRITIONAL; Diagnosis/Diseases Component; =Diabetes Mellitus, Insulin-Dependent; adult onset diabetes mellitus; Diabetic Angiopathies; Diabetes with ketoacidosis; Diabetes with renal manifestations; Diabetes with neurological manifestations; Diabetes in Pregnancy; drug related diabetes mellitus; prediabetic state; virus related diabetes mellitus; diabetic cardiomyopathy; diabetic ophthalmopathy; Diabetes Mellitus, Experimental; Diabetes Mellitus, Insulin-Dependent; Diabetes Mellitus, Lipoatrophic; adult onset diabetes mellitus; Diabetic Angiopathies; Diabetes with ketoacidosis; Diabetes with renal manifestations; Diabetes with neurological manifestations; Obesity in Diabetes; Diabetes mellitus, antepartum; Diabetes in Pregnancy; prediabetic state; diabetic coma;
|
- 146. 3,7-Dihydro-3,7-dimethyl-1-(5-oxohexyl)-1H-purine-2,6-dione
- [metabolite of pentifylline (a preparation of theobromine and hexyl halide); used as a vasodilator. ( CSP )] (UMLS (NCI) C0030899) =Organic Chemical; Pharmacologic Substance ;
=theobromine;
Vasodilating Agent;
[CV900] CARDIOVASCULAR AGENTS, OTHER;
=PENTOXIFYLLINE 400 MG;
| - 196. diabetes mellitus diet
- [A diet that uses carbohydrates sparingly. Typically with a restriction in daily energy content (e.g. 1600-2000 kcal). ( HL7V3.0 )] (UMLS (HL7) C1550566) =Intellectual Product =Diet;
|
- 147. 3,7-Dimethyl-9-(2,6, 6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol
- [Vitamin A. It is essential for proper vision and healthy skin and mucous membranes. Retinol is being studied for cancer prevention; it belongs to the family of drugs called retinoids. ( NCI )] (UMLS (NCI) C0087161) =Organic Chemical; Pharmacologic Substance; Vitamin =Retinoic Acid Agent;
| - 197. diabetes mellitus genetics
- [heredity of diabetes mellitus, especially the mechanisms of hereditary transmission and the variation of inherited characteristics of diabetes mellitus; the genetic constitution of an individual as it relates to diabetes mellitus. ( CSP )] (UMLS (CSP) C0596425) =Occupation or Discipline =Genetics;
|
- 148. 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)2-trans-4-trans-6-cis-8-trans-nonatetraenoic Acid
- [A drug being studied for cancer prevention. It belongs to the family of drugs called retinoids. ( NCI )] (UMLS (NCI) C0281666) =Organic Chemical; Pharmacologic Substance; Vitamin =(All-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic Acid;
[DE600] ANTINEOPLASTICS, TOPICAL =ALITRETINOIN 0.1 % | - 198. diabetes mellitus nursing
- [ ] (UMLS (CSP) C0599003) =Biomedical Occupation or Discipline ;
|
- 149. 3-(((Dimethylamino)carbonyl)oxy)-1-methylpyridinium Bromide
- [The bromide salt form of pyridostigmine, a quaternary ammonium carbamate derivative and a acetylcholinesterase inhibitor. Pyridostigmine bromide binds reversibly to acetylcholinesterase active sites in the peripheral nervous system, thereby preventing the breakdown of acetylcholine. This leads to an accumulation of acetylcholine at cholinergic synapses and facilitates transmission of impulses across the neuromuscular junction. Mediated through muscarinic receptors, this agent increases contraction of bronchial and intestinal smooth muscle and the exocrine glands secretions, while it causes paralysis of the skeletal muscles mediated through nicotinic receptors . In addition, pyridostigmine is used as a reversible blocking agent to prevent organophosphates from binding to the acetylcholinesterase receptors and thereby protect the nervous system from the effects of nerve agents such as Soman. ( NCI )] (UMLS (NCI) C0034262) =Organic Chemical; Pharmacologic Substance ;
=Pyridinium Compounds;
PYRIDOSTIGMINE =PYRIDOSTIGMINE BROMIDE 180 MG;
PYRIDOSTIGMINE BROMIDE 5 MG/ML;
PYRIDOSTIGMINE BROMIDE 60 MG;
PYRIDOSTIGMINE BROMIDE 60 MG/5ML;
| - 199. Diabetes mellitus of mother, with delivery
- [ ] (UMLS (ICD9CM) C0341897) =Disease or Syndrome
|
- 150. 3-(2,5-Dihydroxyphenyl)-2-propenoic Acid Methyl Ester
- [A cell-permeable analog of erbstatin, a compound isolated from Streptomyces that inhibits the autophosphorylation of epidermal growth factor receptor. Erbstatin analogue competitively inhibits epidermal growth factor receptor-associated tyrosine kinase, inhibiting the activation of v-abl tyrosine kinase. In addition, this agent has induced apoptosis in mouse thymocytes and inhibits the G2/M phase of the cell cycle. (NCI) ( NCI )] (UMLS (NCI) C0083406) =Organic Chemical; Pharmacologic Substance
| - 200. Diabetes mellitus of mother, with delivery, with mention of postpartum complication
- [ ] (UMLS (ICD9CM) C0341896) =Disease or Syndrome
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