- 101. 10,11-Dihydro-10-oxo-5H-dibenz(b,f)azepine-5-carboxamide
- [A dibenzazepine carboxamide derivative with an anticonvulsant property. As a prodrug, oxcarbazepine is converted to its active metabolite, 10-monohydroxy. Although the mechanism of action has not been fully elucidated, electrophysiological studies indicate this agent blocks voltage-gated sodium channels, thereby stabilizing hyper-excited neural membranes, inhibiting repetitive neuronal firing, and decreasing the propagation of synaptic impulses. ( NCI )] (UMLS (NCI) C0069751) =Organic Chemical; Pharmacologic Substance =[CN400] ANTICONVULSANTS;
5H-Dibenz(b,f)azepine-5-carboxamide =OXCARBAZEPINE 300 MG;
OXCARBAZEPINE 600 MG;
OXCARBAZEPINE 150 MG;
OXCARBAZEPINE 300 MG/5ML | - 151. 2-(2-(Diethylamino)ethoxy)-3-phenylpropiophenone
- (UMLS (NCI) C0059677) =Organic Chemical; Pharmacologic Substance ;
|
- 102. 10,11delta-Amitriptyline Hydrochloride
- [A centrally acting muscle relaxant, chemically similar to amitriptyline hydrochloride with antidepressant activity. The exact mechanism of action of cyclobenzaprine hydrochloride has not been fully determined. However, it primarily acts at the brain stem to reduce tonic somatic motor activity, influencing both gamma and alpha motor neurons. This leads to a reduction in muscle spasms. ( NCI )] (UMLS (NCI) C0125988) =Organic Chemical; Pharmacologic Substance ;
=CYCLOBENZAPRINE;
=CYCLOBENZAPRINE HYDROCHLORIDE 10 MG | - 152. 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one
- [antioxidant flavonol widely distributed in plants. ( CSP )] (UMLS (NCI) C0034392) =Organic Chemical; Pharmacologic Substance; Vitamin =flavonoid;
vasoactive agent |
- 103. 10-(3-(Dimethylamino)propyl)phenothiazine Monohydrochloride
- [The hydrochloride salt form of promazine, a phenothiazine derivative with antipsychotic and antiemetic properties. Promazine hydrochloride blocks postsynaptic dopamine receptors D1 and D2 in the mesolimbic and medullary chemoreceptor trigger zone (CTZ), thereby decreasing stimulation of the vomiting center in the brain and psychotic effects, such as hallucinations and delusions. In addition, this agent blocks alpha-adrenergic receptors and exhibits strong anticholinergic activity. ( NCI )] (UMLS (NCI) C0546875) =Organic Chemical; Pharmacologic Substance =PROMAZINE;
=PROMAZINE HYDROCHLORIDE 50 MG/ML;
| - 153. 2-(3,4-Dihydroxyphenyl)ethanol
- (UMLS (NCI) C0376776) =Organic Chemical; Pharmacologic Substance ;
|
- 104. 10-Deacetyltaxol
- [An analog of paclitaxel with antineoplastic activity. 10-Deacetyltaxol binds to and stabilizes the resulting microtubules, thereby inhibiting microtubule disassembly which results in cell- cycle arrest at the G2/M phase and apoptosis. ( NCI )] (UMLS (NCI) C0044663) =Organic Chemical
| - 154. 2-(3,7,11,15,19,23,27,31,35,39-Decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecanyl)-5,6-dimethoxy-3-methyl-2,5-cyclohexadiene-1,4-dione
- [family of isoprenoid quinones which serve as mitochondrial electron transport cofactors. ( CSP )] (UMLS (NCI) C0041536) =Organic Chemical; Pharmacologic Substance; Biologically Active Substance =Benzoquinone Compound;
cofactor |
- 105. 11D10
- [A murine monoclonal anti-idiotype antibody (anti-Id). Anti-Id 11D10 mimics a specific epitope of the high molecular weight human milk fat globule (HMFG) glycoprotein primarily expressed by human breast and some other tumor cells at high density. This specific HMFG epitope is identified by mAb BrE1, which was used as the immunizing antibody or Ab1 to generate the anti-Id (Ab2) 11D10. Anti-ID 11D10 reacts specifically with breast tumor cells and with minimal reactivity with normal tissues. Vaccination with anti-Id 11D10 induces anti-anti-idiotype antibodies (Ab3) that may react with breast cancer cell lines expressing the HMFG membrane epitope. ( NCI )] (UMLS (NCI) C0677765) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor
| - 155. 2-(4-(((3,5-Dimethylanilino)Carbonyl)Methyl)Phenoxy)-2-Methylpropionic Acid
- [A synthetic small molecule with radiosensitizing activity. Efaproxiral increases oxygen levels in hypoxic tumor tissues by binding non-covalently to the hemoglobin tetramer and decreasing hemoglobin-oxygen binding affinity. Increasing tumor oxygenation reduces tumor radioresistance. (NCI04) ( NCI )] (UMLS (NCI) C0080719) =Organic Chemical; Pharmacologic Substance
|
- 106. 11D10 Anti-Idiotype Vaccine
- [A vaccine consisting of a monoclonal antibody (MoAB) directed against an idiotype that mimics a human milk fat globule (HMFG) membrane epitope. Vaccination with monoclonal antibody 11D10 anti-idiotype vaccine induces anti-anti-idiotype antibodies (Ab3) that may react with breast cancer cell lines expressing the HMFG membrane epitope. (NCI04) ( NCI )] (UMLS (NCI) C0935720) Monoclonal Antibody 11D10 Anti-Idiotype Vaccine;
TriAb anti-idiotype antibody =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor | - 156. 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide Monohydrochloride
- [The hydrochloride salt from of lidocaine, an aminoethylamide and a prototypical member of the amide class anesthetics. Lidocaine interacts with voltage-gated Na+ channels in the nerve cell membrane and blocks the transient increase in permeability of excitable membranes to Na+. This prevents the generation and conduction of nerve impulses and produces a reversible loss of sensation. Lidocaine hydrochloride also exhibits class IB antiarrhythmic effects. The agent decreases the flow of sodium ions into myocardial tissue, especially on the Purkinje network, during phase 0 of the action potential, thereby decreasing depolarization, automaticity and excitability. ( NCI )] (UMLS (NCI) C0546869) =Organic Chemical; Pharmacologic Substance =[CV300] ANTIARRHYTHMICS;
.omega.-Diethylamino-2,6-dimethylacetanilide;
[CN204] LOCAL ANESTHETICS, INJECTION;
[GU900] GENITOURINARY AGENTS, OTHER =LIDOCAINE HCL MISC. POWDER (GM);
LIDOCAINE HYDROCHLORIDE 1 %;
LIDOCAINE HYDROCHLORIDE 1 %WV;
LIDOCAINE HYDROCHLORIDE 100 MG/ML;
LIDOCAINE HYDROCHLORIDE 160 MG;
LIDOCAINE HYDROCHLORIDE 2.5 %;
LIDOCAINE HYDROCHLORIDE 300 MG;
LIDOCAINE HYDROCHLORIDE 4 %;
LIDOCAINE HYDROCHLORIDE 10 MG/ML;
LIDOCAINE HYDROCHLORIDE 0.5 %;
LIDOCAINE HYDROCHLORIDE 5 %;
LIDOCAINE HYDROCHLORIDE 1 GM;
LIDOCAINE HYDROCHLORIDE 200 MG/ML;
LIDOCAINE HYDROCHLORIDE 2 GM;
LIDOCAINE HYDROCHLORIDE 2 MG/ML;
LIDOCAINE HYDROCHLORIDE 4 MG/ML;
LIDOCAINE HYDROCHLORIDE 20 MG/ML;
LIDOCAINE HYDROCHLORIDE 1.5 %;
LIDOCAINE HYDROCHLORIDE 40 MG/ML;
LIDOCAINE HYDROCHLORIDE 8 MG/ML;
LIDOCAINE HYDROCHLORIDE 2 %;
|
- 107. 14-Diethoxyacetoxydaunorubicin
- [A semi-synthetic derivative of the anthracycline antineoplastic antibiotic daunorubicin. Detorubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent also produces toxic free-radical intermediates and interacts with cell membrane lipids causing lipid peroxidation. Detorubicin is less toxic than daunorubicin. (NCI04) ( NCI )] (UMLS (NCI) C0057578) =Organic Chemical; Pharmacologic Substance ;
| - 157. 2-(DIETHYLAMINO)ETHANOL
- (UMLS (NCI) C0046079) =Organic Chemical; Pharmacologic Substance ;
|
- 108. 15 day report
- (UMLS (HL7) C1546918) =Temporal Concept =Report timing;
| - 158. 2-(Diethylamino)ethyl 3-amino-4-propoxybenzoate Monohydrochloride
- [The hydrochloride salt form of proparacaine, a benzoic acid derivative with local anesthetic property. Proparacaine hydrochloride stabilizes the neuronal membrane by binding to and inhibiting voltage-gated sodium channels, thereby inhibiting sodium ion influx required for the initiation and conduction of impulses within the neuronal cell, and resulting in a loss of sensation. ( NCI )] (UMLS (NCI) C0740235) Benzoic Acid, 3-amino-4-propoxy-, 2-(diethylamino)ethyl Ester, Hydrochloride;
Proparacaine Hydrochloride;
PROPARACAINE HYDROCHLORIDE PREPARATION =Organic Chemical; Pharmacologic Substance =Proparacaine;
=PROPARACAINE HYDROCHLORIDE 0.5 % |
- 109. 15-Deoxyspergualin Hydrochloride
- (UMLS (NCI) C0284558) =Organic Chemical; Pharmacologic Substance ;
| - 159. 2-(Diethylamino)ethyl p-aminobenzoate Monohydrochloride
- [The hydrochloride salt form of procaine, a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodium channels, thereby inhibiting the ionic flux required for the initiation and conduction of impulses. In addition, this agent increases electrical excitation threshold, reduces rate of rise of action potential and slows nerve impulse propagation thereby causing loss of sensation. ( NCI )] (UMLS (NCI) C0358490) =Organic Chemical; Pharmacologic Substance =PROCAINE;
=PROCAINE HYDROCHLORIDE 1 %;
PROCAINE HYDROCHLORIDE 2 %;
PROCAINE HYDROCHLORIDE 1.25 %;
PROCAINE HYDROCHLORIDE 10 %;
|
- 110. 17,21-Dihydroxypregn-4-ene-3,11,20-trione
- [naturally occurring glucocorticoid used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent; cortisone itself is inactive and is converted in the liver to the active metabolite cortisol. ( CSP )] (UMLS (NCI) C0010137) =Steroid; Pharmacologic Substance; Hormone ;
=[HS051] GLUCOCORTICOIDS;
Pregnenes =21-(Acetyloxy)-17-hydroxypregn-4-ene-3,11,20-trione;
CORTISONE 25 MG;
| - 160. 2-(Difluoromethyl)-DL-ornithine
- [polyamine antagonist which reversibly inhibits DNA polymerase and irreversibly inhibits ornithine decarboxylase; used against bladder cancer, with potential applications in epilepsy and PCP withdrawal. ( CSP )] (UMLS (NCI) C0086156) =Amino Acid, Peptide, or Protein; Pharmacologic Substance ;
=[AN000] ANTINEOPLASTICS;
Antiprotozoal Agent;
fluoroaminoacid;
|
- 111. 17-Demethoxy-15-methoxy-11-O-methylgeldanamycin, (15R)-
- [A benzoquinone antineoplastic antibiotic isolated from the bacterium Streptomyces hygroscopicus. Herbimycin binds to and inhibits the cytosolic chaperone functions of heat shock protein 90 (HSP90). HSP90 maintains the stability and functional shape of many oncogenic signaling proteins; the inhibition of HSP90 promotes the proteasomal degradation of oncogenic signaling proteins that may be over-expressed or overactive in tumor cells. (NCI04) ( NCI )] (UMLS (NCI) C0062565) =Organic Chemical; Antibiotic ;
| - 161. 2-(Difluoromethyl)-dl-ornithine Hydrochloride, Monohydrate
- [The hydrochloride form of eflornithine, a difluoromethylated ornithine compound with antineoplastic activity. Eflornithine irreversibly inhibits ornithine decarboxylase, an enzyme required for polyamine biosynthesis, thereby inhibiting the formation and proliferation of tumor cells. Polyamines are involved in nucleosome oligomerization and DNA conformation, creating a chromatin environment that stimulates neoplastic transformation of cells. (NCI04) ( NCI )] (UMLS (NCI) C0282042) =Amino Acid, Peptide, or Protein; Pharmacologic Substance =Alpha-Difluoromethylornithine;
=EFLORNITHINE HYDROCHLORIDE 13.9 % |
- 112. 17d
- [Mandibular left third molar distal hemisection ( HL7V3.0 )] (UMLS (HL7) C1552104) =Body Part, Organ, or Organ Component =Permanent dentition;
| - 162. 2-Deoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose
- [2-deoxy-2-(3-methyl-3-nitrosoureido) -D-glucopyranose; USP antineoplastic antibiotic; at high doses it destroys pancreatic beta cells and can be used to create experimental animal models of diabetes mellitus. ( CSP )] (UMLS (NCI) C0038432) =Carbohydrate; Antibiotic ;
=[AM300] AMINOGLYCOSIDES;
antineoplastic antibiotics;
nitrosourea;
=STREPTOZOCIN 1 GM/VIL;
|
- 113. 18d
- [Mandibular left second molar distal hemisection ( HL7V3.0 )] (UMLS (HL7) C1552106) =Body Part, Organ, or Organ Component =Permanent dentition;
| - 163. 2-Deoxyphenobarbital
- [An analog of phenobarbital with antiepileptic property. Although the mechanism of action has not been fully elucidated, primidone probably exerts its actions, in a manner similar to phenobarbital, via activation of gamma-aminobutyric acid (GABA)-A receptor/chloride ionophore complex, which leads to prolonged and increased frequency of opening of the chloride channel within the receptor complex. This results in an alteration in the electrical activity of the nerve cell membrane, causing hyperpolarization and prevention of partial and tonic-clonic seizures. In addition, this agent is partially metabolized to phenobarbital and phenylethylmalonamide (PEMA), which may also contribute to its anti-seizure properties. ( NCI )] (UMLS (NCI) C0033148) =Organic Chemical; Pharmacologic Substance =[CN400] ANTICONVULSANTS;
5-Ethyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione =PRIMIDONE 250 MG;
PRIMIDONE 50 MG;
PRIMIDONE 250 MG/5ML |
- 114. 19d
- [Mandibular left first molar distal hemisection ( HL7V3.0 )] (UMLS (HL7) C1552108) =Body Part, Organ, or Organ Component =Permanent dentition;
| - 164. 2-Diethylaminoethyl 4-amino-2-chlorobenzoate Hydrochloride
- [A synthetic, aminoester, local, anesthetic agent. At the injection site, chloroprocaine hydrochloride acts by inhibiting sodium influx through binding to specific membrane sodium ion channels in the neuronal cell membranes, restricting sodium permeability, and blocking nerve impulse conduction. This leads to a loss of sensation. Chloroprocaine hydrochloride is short-acting due to rapid hydrolysis by pseudocholinesterase into para-aminobenzoic acid in plasma. ( NCI )] (UMLS (NCI) C0132182) =Organic Chemical; Pharmacologic Substance ;
=chloroprocaine;
=CHLOROPROCAINE HYDROCHLORIDE 2 %;
CHLOROPROCAINE HYDROCHLORIDE 1 %;
CHLOROPROCAINE HYDROCHLORIDE 3 %;
|
- 115. 1D1O Anti-lymphoma Antibody
- [A type of monoclonal antibody that is being studied as a treatment for hematologic (blood) cancers. ( NCI )] (UMLS (NCI) C1122758) Apolizumab =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor
| - 165. 2-[(2,6-Dichlorophenyl)amino]benzeneacetic Acid
- [A nonsteroidal benzeneacetic acid derivative with anti-inflammatory activity. As a nonsteroidal anti-inflammatory drug (NSAID), diclofenac binds and chelates both isoforms of cyclooxygenase (COX-1 and-2), thereby blocking the conversion of arachidonic acid to pro-inflammatory-proprostaglandins. This agent also may inhibit COX-2-mediated tumor angiogenesis. When inhibiting COX-2, diclofenac may be effective in relieving pain and inflammation; when inhibiting COX-1, it may produce unacceptable gastrointestinal side effects. This agent may be more active against COX-2 than several other carboxylic acid-containing NSAIDs. (NCI04) ( NCI )] (UMLS (NCI) C0012091) =Organic Chemical; Pharmacologic Substance =phenylacetate;
[MS102] NONSALICYLATE NSAIS, ANTIRHEUMATIC;
[OP300] ANTI-INFLAMMATORIES, TOPICAL OPHTHALMIC;
=2-[(2,6-Dichlorophenyl)amino]benzeneacetic Acid Monosodium Salt;
2-((2,6-Dichlorophenyl)amino)-benzeneacetic Acid, Monopotassium Salt;
2-[(2,6-Dichlorophenyl)amino]benzeneacetic Acid Monosodium Salt;
|
- 116. 2 DEG BURN BACK OF HAND
- [ ] (UMLS (ICD9CM) C0161228) =Injury or Poisoning
| - 166. 2-[(2,6-Dichlorophenyl)amino]benzeneacetic Acid Monosodium Salt
- [The sodium salt form of diclofenac, a benzene acetic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with analgesic, antipyretic and anti-inflammatory activity. Diclofenac sodium is a non-selective reversible and competitive inhibitor of cyclooxygenase (COX), subsequently blocking the conversion of arachidonic acid into prostaglandin precursors. This leads to an inhibition of the formation of prostaglandins that are involved in pain, inflammation and fever. ( NCI )] (UMLS (NCI) C0700583) =Organic Chemical; Pharmacologic Substance =2-[(2,6-Dichlorophenyl)amino]benzeneacetic Acid;
=2-((2,6-Dichlorophenyl)amino)-benzeneacetic Acid, Monopotassium Salt;
DICLOFENAC SODIUM 0.1 %;
DICLOFENAC SODIUM 50 MG;
DICLOFENAC SODIUM 75 MG;
DICLOFENAC SODIUM 100 MG;
DICLOFENAC SODIUM 25 MG;
DICLOFENAC SODIUM 3 % |
- 117. 2 DEG BURN FINGR W THUMB
- [ ] (UMLS (ICD9CM) C0161226) =Injury or Poisoning
| - 167. 2-[3-(Dimethyl-amino)propyl]-8,8-diethyl-2-aza-8-germaspiro[4,5]decane
- [A synthetic organometallic compound containing the element germanium with possible antineoplastic activity. Spirogermanium exhibits significant toxicity, particularly neurotoxicity. (NCI04) ( NCI )] (UMLS (NCI) C0075018) =Organic Chemical; Pharmacologic Substance ;
|
- 118. 2 Dimensional Gel Electrophoresis
- [A technique in which proteins are first separated across a gel, usually polyacrylamide, according to their isoelectric point, and then separated in a perpendicular direction on the basis of their molecular weight. ( NCI )] (UMLS (NCI) C0013860) =Laboratory Procedure ;
=gel electrophoresis;
| - 168. 3 day report
- (UMLS (HL7) C1546920) =Temporal Concept =Report timing;
|
- 119. 2',3'-Dideoxyadenosine
- [A synthetic nucleoside analogue of deoxyadenosine and a prodrug of didanosine in which the 3' hydroxyl group on the ribose moiety is replaced by a hydrogen atom. Dideoxyadenosine competitively inhibits adenylyl cyclase, thereby reducing levels of cyclic adenosine monophosphate (cAMP). By inhibiting cAMP-mediated gene activation in tumor cells, this agent may retard tumor cell proliferation. (NCI04) ( NCI )] (UMLS (NCI) C0012131) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
| - 169. 3 DEG BRN W LOSS LEG-MLT
- [ ] (UMLS (ICD9CM) C0161314) =Injury or Poisoning
|
- 120. 2',3'-Dideoxycytidine
- [cytidine analog which inhibits reverse transcriptase and has potential efficacy against AIDS. ( CSP )] (UMLS (NCI) C0012132) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance =[AM800] ANTIVIRALS;
deoxycytidine;
2',3'-Dideoxycytidine;
Dideoxynucleosides;
2'3' dideoxynucleoside;
=2',3'-Dideoxycytidine;
2'3' dideoxy 3' thiacytidine;
ZALCITABINE (DIDEOXYCYTIDINE,ddC) 0.375 MG;
ZALCITABINE (DIDEOXYCYTIDINE,ddC) 0.75 MG;
2',3'-Dideoxycytidine;
| - 170. 3 DEG BRN W LOSS-LEG NOS
- [ ] (UMLS (ICD9CM) C0161307) =Injury or Poisoning
|
- 121. 2',3'-Dideoxyinosine
- [inosine nucleoside analog; antiHIV agent. ( CSP )] (UMLS (NCI) C0012133) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance =[AM800] ANTIVIRALS;
Dideoxynucleosides;
inosine;
2'3' dideoxynucleoside =DIDANOSINE 100 MG;
DIDANOSINE 150 MG;
DIDANOSINE 25 MG;
DIDANOSINE 50 MG;
DIDANOSINE 125 MG;
DIDANOSINE 400 MG;
DIDANOSINE 200 MG;
DIDANOSINE 250 MG;
DIDANOSINE 10 MG/ML;
DIDANOSINE 167 MG | - 171. 3 DEG BRN W LOSS-LOW LEG
- [ ] (UMLS (ICD9CM) C0161311) =Injury or Poisoning
|
- 122. 2'-Deoxy-5-azacytidine
- [An anticancer drug that belongs to the family of drugs called antimetabolites. ( NCI )] (UMLS (NCI) C0049065) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
| - 172. 3 DEG BURN BACK OF HAND
- [ ] (UMLS (ICD9CM) C0161238) =Injury or Poisoning
|
- 123. 2'-Deoxy-5-trifluoromethyluridine
- [A fluorinated thymidine analog with potential antineoplastic activity. Trifluridine is incorporated into DNA and inhibits thymidylate synthase, resulting in inhibition of DNA synthesis, inhibition of protein synthesis, and apoptosis. This agent also exhibits antiviral activity. (NCI04) ( NCI )] (UMLS (NCI) C0040987) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
=dT;
[OP203] ANTIVIRALS, TOPICAL OPHTHALMIC =TRIFLURIDINE 1 % | - 173. 3 DEG BURN FINGR W THUMB
- [ ] (UMLS (ICD9CM) C0161236) =Injury or Poisoning
|
- 124. 2'-Deoxycytidine Kinase
- [Deoxycytidine Kinase, encoded by the DCK gene, is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. (from LocusLink) ( NCI )] (UMLS (NCI) C0011486) =Amino Acid, Peptide, or Protein; Enzyme ;
| - 174. 3 DEG BURN W LOSS-ANKLE
- [ ] (UMLS (ICD9CM) C0161310) =Injury or Poisoning
|
- 125. 2'-Deoxythymidine
- [A pyrimidine nucleoside component of DNA comprised of thymidine linked by its N1 nitrogen to the C1 carbon of deoxyribose. ( NCI )] (UMLS (NCI) C0086126) =Nucleic Acid, Nucleoside, or Nucleotide; Biologically Active Substance ;
| - 175. 3 DEG BURN W LOSS-FOOT
- [ ] (UMLS (ICD9CM) C0161309) =Injury or Poisoning
|
- 126. 2'3' dideoxy 3' thiacytidine
- [zalcitabine analog ( CSP )] (UMLS (CSP) C0209738) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
=[AM800] ANTIVIRALS;
2',3'-Dideoxycytidine;
2'3' dideoxynucleoside;
=Lamivudine 10 MG/ML;
LAMIVUDINE 150 MG;
LAMIVUDINE 25 MG/5ML;
LAMIVUDINE 100 MG;
LAMIVUDINE 300 MG | - 176. 3 DEG BURN W LOSS-KNEE
- [ ] (UMLS (ICD9CM) C0161312) =Injury or Poisoning
|
- 127. 2'3' dideoxynucleoside
- [series of antiretroviral nucleoside analogs with potential efficacy against AIDS. ( CSP )] (UMLS (CSP) C0282384) =Nucleic Acid, Nucleoside, or Nucleotide =deoxyribonucleoside;
Reverse Transcriptase Inhibitor;
nucleoside analog;
=2',3'-Dideoxycytidine;
2',3'-Dideoxyinosine;
3'-Azido-3'-deoxythymidine;
1-(2,3-Dideoxy-beta-glycero-pent-2-enofuranosyl)thymine;
2'3' dideoxy 3' thiacytidine;
| - 177. 3 DEG BURN W LOSS-THIGH
- [ ] (UMLS (ICD9CM) C0161313) =Injury or Poisoning
|
- 128. 2, 4-Dioxopyrimidine
- [2,4-diketopyrimidine; one of the 5 major bases (with adenine, guanine, cytosine, and thymine) which are a component of nucleic acids. ( CSP )] (UMLS (NCI) C0041917) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance; Biologically Active Substance =Pyrimidine;
Pyrimidinones;
nucleobase;
=2,4-Dioxo-5-fluoropyrimidine;
thiouracil;
5-(bis-(2-Chloroethyl) Amino) Uracil | - 178. 3 DEG BURN W LOSS-TOE
- [ ] (UMLS (ICD9CM) C0375684) =Injury or Poisoning
|
- 129. 2,2',2'',2''''-[(4,8-Dipiperidinopyrimido-[5,4-d]pyrimidine-2,6-diyl)dinitrilo]tetraethanol
- [platelet inhibitor and coronary vasodilator used to prevent thromboembolism associated with mechanical heart valves, as prophylactic adjunct in the prevention of myocardial reinfarction, and as a diagnostic aid adjunct in myocardial perfusion imaging; administered orally and intravenously. ( CSP )] (UMLS (NCI) C0012582) =Organic Chemical; Pharmacologic Substance ;
=piperidine;
[BL700] PLATELET AGGREGATION INHIBITORS;
Pyrimidine;
coronary vasodilator =DIPYRIDAMOLE 25 MG;
DIPYRIDAMOLE 5 MG/ML;
DIPYRIDAMOLE 75 MG;
DIPYRIDAMOLE 50 MG;
DIPYRIDAMOLE 200 MG;
| - 179. 3' deoxyadenosine
- [An anticancer drug that belongs to a family of drugs called antitumor antibiotics. ( NCI )] (UMLS (CSP) C0056331) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
|
- 130. 2,2'-Dichloro-4,4'-methylenedianiline
- [A tan-colored, solid, chlorinated aromatic amine with an amine-like odor that emits toxic fumes of hydrochloric acid and other chlorinated compounds when heated to decomposition. 4,4-Methylenebis-2-chloroaniline is primarily used in industry as a curing agent for liquid polyurethane elastomers and is used as an experimental carcinogen in research. Exposure to this substance can cause gastrointestinal distress and severe irritation of the face and eyes. 4,4-Methylenebis-2-chloroaniline is reasonably anticipated to be a human carcinogen and may be associated with an increased risk of developing bladder cancer. (NCI05) ( NCI )] (UMLS (NCI) C0025750) =Organic Chemical; Hazardous or Poisonous Substance ;
| - 180. 3', 5'-Dichloroamethopterin
- [A chlorinated methotrexate derivative. Dichloromethotrexate inhibits the enzyme dihydrofolate reductase, thereby preventing the synthesis of purine nucleotides and thymidylates and inhibiting DNA and RNA synthesis. This agent is metabolized and excreted by the liver. (NCI04) ( NCI )] (UMLS (NCI) C0046764) =Organic Chemical; Pharmacologic Substance
|
- 131. 2,2'-Dithio-bis-ethanesulfonate, Disodium Salt
- [A drug that belongs to the family of drugs called chemoprotective agents. ( NCI )] (UMLS (NCI) C0114346) =Organic Chemical; Pharmacologic Substance
| - 181. 3',4'-Didehydro-4'-deoxy-C'-norvincaleukoblastine
- [An anticancer drug that belongs to the family of plant drugs called vinca alkaloids. ( NCI )] (UMLS (NCI) C0078257) =Organic Chemical; Pharmacologic Substance ;
=[AN000] ANTINEOPLASTICS;
VINBLASTINE =NVB |
- 132. 2,3 dimercaptosuccinic acid
- [ ] (UMLS (CSP) C0205739) =Organic Chemical; Pharmacologic Substance; Indicator, Reagent, or Diagnostic Aid
| - 182. 3'-Deoxyadenosine-5'-(tetrahydrogen triphosphate)
- [The triphosphate salt of Cordycepin, a purine nucleoside antimetabolite analogue and antibiotic isolated from the fungus Cordyceps militaris with potential antineoplastic activity. Cordycepin incorporates into RNA, and, inhibits RNA chain elongation and synthesis due to the absence of a hydroxyl moiety at the 3' position. Because it is converted to an inactive metabolite by adenosine deaminase, this agent must be administered with an adenosine deaminase inhibitor in order to be effective. Cordycepin has displayed cytotoxicity against some leukemic cell lines in vitro. (NCI04) ( NCI )] (UMLS (NCI) C0046803) =Nucleic Acid, Nucleoside, or Nucleotide; Antibiotic
|
- 133. 2,3-Dibromo-1-propanol Phosphate(3:1)
- [A synthetic, colorless or pale yellow liquid that is insoluble in water and miscible with carbon tetrachloride, chloroform and methylene chloride. TRIS-BP is no longer used in the United States. The primary routes of human exposure to TRIS-BP are inhalation, dermal contact and ingestion. Since this compound is no longer produced in the United States, the risk of exposure is low. However, TRIS-BP persists in fabric and plastics, making occupational and consumer exposure possible. Contact with this chemical can irritate the eyes and skin. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0077281) =Organophosphorus Compound; Hazardous or Poisonous Substance ;
| - 183. 3,12-Diaza-6,9-diazoniadispiro(5.2.5.2)hexadecane, 3,12-bis(3-chloro-2-hydroxypropyl)-, dichloride
- [An dispiropiperazine derivative with potential cytostatic, anti-inflammatory and immune-suppressive properties. Although the exact mechanism of action of prospidin is not known, this agent was shown to interact with DNA, disrupting cell cycle at G2 phase, inhibiting phagocytic activity of monocytes and macrophage. Prospidin has good anti-lupus activity due to its immunosuppressive effects and was also used in refractory rheumatoid arthritis as an anti-rheumatic drug. (NCI04) ( NCI )] (UMLS (NCI) C0033524) =Organic Chemical; Pharmacologic Substance
|
- 134. 2,3-Dihydro-1H-imidazo(1,2-b)pyrazole
- [A synthetic agent, also known as IMPY, with antineoplastic properties. IMPY inhibits ribonucleotide reductase, an enzyme that converts ribonucleotides to deoxyribonucleotides during DNA synthesis; this agent specifically binds the smaller, nonheme-iron subunit of the enzyme. (NCI04) ( NCI )] (UMLS (NCI) C0045368) =Organic Chemical; Pharmacologic Substance ;
| - 184. 3,3'-Diindolymethane
- [A phytonutrient and plant indole found in cruciferous vegetables including broccoli, Brussels sprouts, cabbage, cauliflower and kale, with potential anti-androgenic and antineoplastic activities. As a dimer of indole-3-carbinol, diindolylmethane (DIM) promotes beneficial estrogen metabolism in both sexes by reducing the levels of 16-hydroxy estrogen metabolites and increasing the formation of 2-hydroxy estrogen metabolites, resulting in increased antioxidant activity. Although this agent induces apoptosis in tumor cells in vitro, the exact mechanism by which DIM exhibits its antineoplastic activity in vivo is unknown. ( NCI )] (UMLS (NCI) C1100708) 3,3'-Methylenebis-1H-indole;
CCRIS 5806;
Diindolylmethane;
=Organic Chemical; Pharmacologic Substance ;
|
- 135. 2,3-Dihydro-3-hydroxy-2-imino-6-(1-piperidinyl)-4-pyrimidinamine
- [potent long acting orally effective vasodilator, acting mainly on arterioles, used as an antihypertensive; also applied topically in the treatment of male pattern baldness of the vertex. ( CSP )] (UMLS (NCI) C0026196) =Organic Chemical; Pharmacologic Substance =antihypertensive agent;
Piperidines;
Pyrimidine;
[CV490] ANTIHYPERTENSIVES, OTHER;
DAP;
[DE900] DERMATOLOGICALS, TOPICAL OTHER =MINOXIDIL 10 MG;
MINOXIDIL 2.5 MG;
MINOXIDIL 2 %;
MINOXIDIL 5 %;
| - 185. 3,3'-Dimethoxybenzidine
- [A colorless, highly toxic, crystalline compound that turns violet when exposed to air. Dianisidine is used exclusively as an intermediate for the production of dyes and pigments. Exposure to this substance causes skin irritation and sensitization. Dianisidine is reasonably anticipated to be a human carcinogen based on evidence of carcinogenicity in experimental animals. (NCI05) ( NCI )] (UMLS (NCI) C0011969) =Organic Chemical; Hazardous or Poisonous Substance ;
|
- 136. 2,3-Dihydroxy-2-(1-methylethyl)butanoic Acid (2,3,5,7a-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl)methyl Ester N-Oxide
- [A natural pyrrolizidine alkaloid with antineoplastic properties. Indicine-N-oxide alkylates and crosslinks DNA. (NCI04) ( NCI )] (UMLS (NCI) C0063465) =Organic Chemical; Pharmacologic Substance ;
| - 186. 3,3'-Dimethyl-4,4'-biphenyldiamine
- [A white to reddish colored, combustible, aromatic amine that emits toxic fumes of nitrogen oxides when heated to decomposition. o-Tolidine is used in industry as a dye or as an intermediate in the manufacture of dyes and pigments and is also used in clinical laboratories for the detection of blood. Exposure to this substance irritates the eyes, skin and respiratory tract and damages the kidneys and liver. o-Tolidine is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0046581) =Organic Chemical; Hazardous or Poisonous Substance
|
- 137. 2,3-Dihydroxybutanedioic Acid
- [A white crystalline dicarboxylic acid found in many plants, particularly tamarinds and grapes. Tartaric acid is used to generate carbon dioxide through interaction with sodium bicarbonate following oral administration. Carbon dioxide extends the stomach and provides a negative contrast medium during double contrast radiography. In high doses, this agent acts as a muscle toxin by inhibiting the production of malic acid, which could cause paralysis and maybe death. ( NCI )] (UMLS (NCI) C0075821) =Organic Chemical; Indicator, Reagent, or Diagnostic Aid; Hazardous or Poisonous Substance =tartrate;
Inactive Ingredient Preparations =STANNOUS TARTRATE;
TARTARIC;
DIPYRIDAMOLE 5 MG INTRAVENOUS INJECTION;
TARTARIC ACID PWDR;
TARTARIC ACID 0.42 GM | - 187. 3,3-Dichloro-(1,1-Biphenyl)-4,4-Diamine
- [A synthetic, light-sensitive, gray to purple crystalline solid that is insoluble in cold water but is soluble in ether, benzene, glacial acetic acid and alcohol. It is used primarily in the manufacture of pigments for printing ink, textiles, paper, paint, rubber, and plastics and as a curing agent for isocyanate-containing polymers and solid urethane plastics. When heated to decomposition, 3,3-dichlorobenzidine emits toxic fumes of chlorinated compounds and nitrogen oxides. The primary routes of potential human exposure to 3,3-dichlorobenzidine are inhalation of airborne dust, ingestion of contaminated well water by those living near hazardous waste sites, and dermal contact, primarily during industrial operations. Contact with this compound may cause dermatitis. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0000370) =Organic Chemical; Hazardous or Poisonous Substance ;
|
- 138. 2,4 dinitrophenol
- [toxic dye, chemically related to trinitrophenol (picric acid), used in biochemical studies of oxidative processes where it uncouples oxidative phosphorylation; also used as a metabolic stimulant. ( CSP )] (UMLS (CSP) C0045511) =Organic Chemical; Indicator, Reagent, or Diagnostic Aid ;
=dye;
Haptens;
nitrophenol;
| - 188. 3,4 dihydroxyphenylacetate
- [metabolite of DOPA. ( CSP )] (UMLS (CSP) C0178432) =Organic Chemical ;
=phenylacetate;
|
- 139. 2,4,D/2,4,5,T
- [(2,4-dichlorophenoxy)acetic acid, butyl ester, mixture with butyl (2,4,5-trichlorophenoxy)acetate; an herbicide and chemical defoliant. ( CSP )] (UMLS (NCI) C0050961) =Organic Chemical; Hazardous or Poisonous Substance =herbicide;
| - 189. 3,4,5,6-Dibenzocarbazole
- [A crystalline, carcinogenic aromatic hydrocarbon consisting of five fused rings and produced during the incomplete combustion of organic matter. 7H-Dibenzo[c,g]carbazole is primarily found in cigarette tar. This substance is used only for research purposes. 7H-Dibenzo[c,g]carbazole is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0049973) =Organic Chemical; Hazardous or Poisonous Substance
|
- 140. 2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine
- [antibacterial used in combination with a sulfonamide to treat some urinary tract infections and pneumocystis pneumonia, and alone as an antimalarial. ( CSP )] (UMLS (NCI) C0041041) =Organic Chemical; Pharmacologic Substance ;
=Pyrimidine;
antibacterial agent;
DAP;
[AM900] ANTI-INFECTIVES, OTHER =2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine Sulfate (2:1);
TRIMETHOPRIM 100 MG;
TRIMETHOPRIM 160 MG;
TRIMETHOPRIM 200 MG;
TRIMETHOPRIM 40 MG/5ML;
TRIMETHOPRIM 16 MG/ML;
TRIMETHOPRIM 80 MG;
TRIMETHOPRIM 50 MG/5ML;
| - 190. 3,4-Dihydro-2,2-dimethyl-2H-naphtho(1,2-b)pyran-5,6-dione
- [A naphthoquinone compound derived from bark of Tabebuia sp., with antitumor, antibacterial, antifungal and antitrypanosomal activities. Beta-lapachone exerts its anti-tumor effect by indirect actions of inducing p53-independent apoptosis and cell cycle arrest mediated through altered activities of cell cycle control regulatory proteins; including down-regulating retinoblastoma protein (pRB), a transcriptional repressor target at transcription factor E2F-1, as well as induces expression of cyclin dependent kinase inhibitor 1A (CDKN1A or p21). Both E2F-1 and p21 are required for G1/S-phase transition during cell cycle. This agent also inhibits DNA topoisomerase I by a mechanism distinct from that of camptothecin, and thereby blocks the formation of a cleavable complex leading to enzyme inhibition and prevent DNA repair. Furthermore, beta-lapachone could induce reactive oxygen species in vivo, and result in cytotoxicity. ( NCI )] (UMLS (NCI) C0053471) =Organic Chemical; Pharmacologic Substance ;
|
- 141. 2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine Sulfate (2:1)
- [The sulfate salt form of trimethoprim, a synthetic substituted pyrimidine with antibacterial activity. Trimethoprim sulfate selectively binds to and reversibly inhibits dihydrofolate reductase, thereby blocking the production of tetrahydrofolic acid from dihydrofolic acid. This leads to an inhibition of bacterial synthesis of folic acid, thereby affecting nucleic acid and protein synthesis. Trimethoprim sulfate has a stronger binding affinity for the bacterial enzyme than for the corresponding mammalian enzyme. ( NCI )] (UMLS (NCI) C0724713) Trimethoprim Sulfate;
TRIMETHOPRIM SULFATE PREPARATION;
=Organic Chemical; Pharmacologic Substance ;
=2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine;
=TRIMETHOPRIM SULFATE 0.1 % | - 191. 3,4-Dihydro-2-amino-6-methyl-4-oxy-5-(4-pyridylthio)-quinazoline Dihydrochloride
- [The hydrochloride salt form of nolatrexed, a water-soluble lipophilic quinazoline folate analog with antineoplastic activity. Nolatrexed occupies the folate binding site of thymidylate synthase, resulting in inhibition of thymidylate synthase activity and thymine nucleotide synthesis with subsequent inhibition of DNA replication, DNA damage, S-phase cell cycle arrest, and caspase-dependent apoptosis. This agent also exhibits radiosensitizing activity. (NCI04) ( NCI )] (UMLS (NCI) C0389037) =Organic Chemical; Pharmacologic Substance
|
- 142. 2,4-Diamino-5-methyl-6-[(3,4,5-trimethoxyanilino)methyl]quinazoline mono-D-glucuronate
- [A drug that belongs to the family of drugs called antimetabolites. It is used in the treatment of pneumocystis carinii pneumonia and is being studied in the treatment of cancer. ( NCI )] (UMLS (NCI) C0077209) =Organic Chemical; Pharmacologic Substance ;
| - 192. 3,4-dihydro-3-methyl-4-oxoimidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide
- [dacarbazine derivative; alkylating antineoplastic agent. ( CSP )] (UMLS (NCI) C0076080) =Organic Chemical; Pharmacologic Substance =[AN000] ANTINEOPLASTICS;
1H-imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazenyl)-;
Antineoplastic Alkylating Agent;
=TEMOZOLOMIDE 20 MG;
TEMOZOLOMIDE 100 MG;
TEMOZOLOMIDE 5 MG;
TEMOZOLOMIDE 250 MG;
|
- 143. 2,4-Diamino-6-(2,5-dimethoxybenzyl)-5-methylpyrido[2,3-d]pyrimidine
- [An anticancer drug. ( NCI )] (UMLS (NCI) C0054332) =Organic Chemical; Pharmacologic Substance ;
| - 193. 3,4-dihydroxy-4'-methyl-5-nitrobenzophenone
- [A benzophenone derivative and a catechol-O-methyltransferase (COMT) inhibitor. Tolcapone selectively and reversibly inhibits COMT, an enzyme that catalyzes the metabolism of biologically active catechols and their hydroxylated metabolites by transferring the methyl group of S-adenosyl-L-methionine to the phenolic group of catechol-containing substrates. When given in conjunction with a peripheral dopa decarboxylase inhibitor and levodopa, tolcapone may prevent the metabolism of levodopa to 3-methoxy-4-hydroxy- L-phenylalanine (3-OMD) in the brain and peripheral tissues leading to increased bioavailability and enhancement of delivery to the central nervous system (CNS) of levodopa. ( NCI )] (UMLS (NCI) C0246330) =Organic Chemical; Pharmacologic Substance ;
=[CN500] ANTIPARKINSON AGENTS;
Benzophenones =TOLCAPONE 100 MG;
TOLCAPONE 200 MG;
|
- 144. 2,4-Dichloro-1-(4-nitrophenoxy)benzene
- [A white, crystalline, solid, combustible, chlorinated compound. Nitrofen was used as an herbicide, but is no longer used or manufactured in the United States. Exposure to nitrofen irritates the skin, eyes and respiratory tract and affects the blood and central nervous system. This substance is teratogenic and carcinogenic in animals and is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0068833) =Organic Chemical; Hazardous or Poisonous Substance
| - 194. 3,4-Dihydroxybenzohydroxamic acid
- [3,4-dihydroxybenzohydroxamic acid. An inhibitor of ribonucleotide reductase. ( NCI )] (UMLS (NCI) C0094556) =Organic Chemical; Pharmacologic Substance ;
|
- 145. 2,4-dihydroxy-5-methylpyrimidine
- [2,4-diketo-5-methylpyrimidine; one of the 5 major bases (with adenine, guanine, cytosine, and uracil) found in nucleic acids. ( CSP )] (UMLS (NCI) C0040087) =Nucleic Acid, Nucleoside, or Nucleotide; Biologically Active Substance ;
=Pyrimidine;
nucleobase | - 195. 3,4-Dihydroxyphenylethanol
- (UMLS (NCI) C0046981) =Organic Chemical; Pharmacologic Substance
|
- 146. 2,4-Dioxo-5-fluoropyrimidine
- [pyrimidine analog that is an antineoplastic antimetabolite. ( CSP )] (UMLS (NCI) C0016360) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
=[AN300] ANTINEOPLASTICS, ANTIMETABOLITES;
[AN000] ANTINEOPLASTICS;
2, 4-Dioxopyrimidine;
fluoropyrimidine;
uracil analog;
[DE600] ANTINEOPLASTICS, TOPICAL =FLUOROURACIL 50 MG/ML;
FLUOROURACIL 5 %;
FLUOROURACIL 1 %;
FLUOROURACIL 2 %;
FLUOROURACIL 0.5 %;
| - 196. 3,5-Diacetamido-2,4,6-triiodobenzoic Acid, Sodium Salt
- [An iodinated radiopaque X-ray contrast medium. Diatrizoate sodium blocks X-rays, thereby allowing body structures containing iodine to be delineated in contrast to those structures that do not contain iodine and allowing visualization of these areas. This contrast agent is used as a diagnostic aid in angiography, urography and radiography. (NCI05) ( NCI )] (UMLS (NCI) C0012007) =Organic Chemical; Indicator, Reagent, or Diagnostic Aid =3,5-Bis(acetylamino)-2,4,6-triiodobenzoic Acid;
1-Deoxy-1-(methylamino)-D-glucitol 3,5-diacetamido-2,4,6-triiodobenzoate (salt) =DIATRIZOATE NA PWDR,ORAL;
DIATRIZOATE SODIUM 80 MG/ML;
DIATRIZOATE SODIUM 100 MG;
DIATRIZOATE SODIUM 8 %;
DIATRIZOATE SODIUM 20 %;
DIATRIZOATE SODIUM 35 %;
DIATRIZOATE SODIUM 50 %;
DIATRIZOATE SODIUM 42 %;
DIATRIZOATE SODIUM 25 %;
DIATRIZOATE SODIUM 10 %;
DIATRIZOATE SODIUM 30 %;
DIATRIZOATE SODIUM 29.1 % |
- 147. 2,6 dimethoxyphenylpenicillin
- [semisynthetic penicillin used as an antibacterial in resistant staphylococcal infections. ( CSP )] (UMLS (CSP) C0025643) =Organic Chemical; Antibiotic ;
=Penicillanic Acid;
[AM050] PENICILLINS;
[AM053] PENICILLINASE-RESISTANT PENICILLINS;
=4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 6-((2,6-dimethoxybenzoyl)amino)-3,3-dimethyl-7-oxo-, Monosodium Salt, Monohydrate,(2S-(2alpha,5alpha,6beta))- | - 197. 3,5-Dibromo-N-(4-bromophenyl)-2-hydroxybenzamide
- [A salicylanilide derivative with antibacterial and antifungal activities banned by FDA due to its photosensitizing effect. Tribromsalan is used as disinfectant in medicated soaps. ( NCI )] (UMLS (NCI) C0077019) =Organic Chemical; Pharmacologic Substance ;
|
- 148. 2,6-Diamino-3-(phenylazo)-pyridine Hydrochloride
- [A synthetic, brick-red crystalline solid that is only slightly soluble in cold water and ethanol but is soluble in boiling water, acetic acid, glycerol, ethylene glycol and propylene glycol. It is used orally as a urinary tract analgesic. Side effects of phenazopyridine hydrochloride administration can include nausea, interference with the oxygen-carrying capacity of red blood cells (methemoglobinemia), hemolytic anemia as well as renal and hepatic toxicity. It is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0700555) =Organic Chemical; Pharmacologic Substance ;
=PHENAZOPYRIDINE;
=PHENAZOPYRIDINE HYDROCHLORIDE 100 MG;
PHENAZOPYRIDINE HYDROCHLORIDE 200 MG;
PHENAZOPYRIDINE HYDROCHLORIDE 50 MG;
PHENAZOPYRIDINE HYDROCHLORIDE 150 MG;
| - 198. 3,5-dichloro-2,4-dimethoxy-6-(trichloromethyl) pyridine
- [An anticancer drug that belongs to the family of drugs called alkylating agents. ( NCI )] (UMLS (NCI) C0070220) =Organic Chemical; Pharmacologic Substance
|
- 149. 2-((2,3-Dimethylphenyl)amino)benzoic Acid
- [An anthranilic acid and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activity. Mefenamic acid inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis, by prostaglandin synthase, is responsible for the therapeutic effects of mefenamic acid. Mefenamic acid also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation. ( NCI )] (UMLS (NCI) C0025152) =Organic Chemical; Pharmacologic Substance ;
=Anthranilic Acids;
[CN104] NONSTEROIDAL ANTI-INFLAMMATORY ANALGESICS =Mefenamate 250 MG | - 199. 3,6-Dinitro-2-phenyl-4H-1-benzopyran-4-one
- (UMLS (NCI) C0538186) =Organic Chemical; Pharmacologic Substance ;
|
- 150. 2-((2,6-Dichlorophenyl)amino)-benzeneacetic Acid, Monopotassium Salt
- [The potassium salt form of diclofenac, a benzene acetic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with analgesic, antipyretic and anti-inflammatory activity. Diclofenac potassium is a non-selective reversible and competitive inhibitor of cyclooxygenase (COX), subsequently blocking the conversion of arachidonic acid into prostaglandin precursors. This leads to an inhibition of the formation of prostaglandins that are involved in pain, inflammation and fever. ( NCI )] (UMLS (NCI) C0282131) =Organic Chemical; Pharmacologic Substance ;
=2-[(2,6-Dichlorophenyl)amino]benzeneacetic Acid;
2-[(2,6-Dichlorophenyl)amino]benzeneacetic Acid Monosodium Salt =DICLOFENAC POTASSIUM 50 MG | - 200. 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione
- [1,3-dimethylxanthine; methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. ( CSP )] (UMLS (NCI) C0039771) =Organic Chemical; Pharmacologic Substance; Biologically Active Substance =bronchodilator;
Xanthine Alkaloids;
xanthine;
Muscle Relaxant;
methylpurine;
[RE104] BRONCHODILATORS, XANTHINE-DERIVATIVE =1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-, compound with 1,2-Ethanediamine(2:1);
DIMENHYDRINATE;
1H-Purine-2,6-dione, 7-(2,3-dihydroxypropyl)-3,7-dihydro-1,3-dimethyl;
Choline, hydroxide, compound with Theophylline(1:1);
pamabrom;
Theophylline Anhydrous;
THEOPHYLLINE CALCIUM SALICYLATE;
THEOPHYLLINE SODIUM GLYCINATE;
THEOPHYLLINE CALCIUM SALICYLATE;
THEOPHYLLINE SODIUM GLYCINATE;
THEOPHYLLINE 0.4 MG/ML;
THEOPHYLLINE 0.8 MG/ML;
Theophylline 10 MG/ML;
THEOPHYLLINE 100 MG;
THEOPHYLLINE 120 MG;
THEOPHYLLINE 125 MG;
THEOPHYLLINE 2 MG/ML;
THEOPHYLLINE 250 MG;
THEOPHYLLINE 3.2 MG/ML;
THEOPHYLLINE 300 MG;
THEOPHYLLINE 4 MG/ML;
THEOPHYLLINE 450 MG;
THEOPHYLLINE 600 MG;
THEOPHYLLINE 1.6 MG/ML;
THEOPHYLLINE 200 MG;
THEOPHYLLINE 400 MG;
THEOPHYLLINE 100 MG/18.75ML;
THEOPHYLLINE 100 MG/15ML;
Theophylline 10.7 MG/ML;
Theophylline 5.9 MG/ML;
THEOPHYLLINE SODIUMGLYCINATE;
THEOPHYLLINE 80 MG/15ML;
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