- 401. Cytarabine/Imatinib Mesylate
- (UMLS (NCI) C1134549) =Therapeutic or Preventive Procedure ;
| - 449. Cytologic Technique
- [Technique for manipulation of cells and analysis of cell properties and subcellular features. ( NCI )] (UMLS (NCI) C0010818) =Laboratory Procedure ;
|
- 402. Cytarabine/Irinotecan
- (UMLS (NCI) C1327859) =Therapeutic or Preventive Procedure
| - 450. Cytology
- [The light microscopic study of normal and abnormal cells in fine needle aspirates (FNAs), body cavity fluids, and smears. — 2004 ( NCI )] (UMLS (NCI) C0010819) =Biomedical Occupation or Discipline ;
|
- 403. Cytarabine/Leucovorin Calcium
- (UMLS (NCI) C0879401) =Therapeutic or Preventive Procedure
| - 451. Cytology and Pathology
- [A branch of pathology that studies and diagnoses diseases on the cellular level including the anatomy, physiology, pathology and chemistry of the cell. ( NCI )] (UMLS (NCI) C0243139) =Occupation or Discipline ;
|
- 404. Cytarabine/Leucovorin Calcium/Methotrexate
- (UMLS (NCI) C1327822) =Therapeutic or Preventive Procedure ;
| - 452. cytolysin
- [group of substances elaborated by microorganisms, plants or animals that are specifically toxic to individual cells; they may be involved in immunity or may be contained in venoms. ( CSP )] (UMLS (CSP) C0010821) =Hazardous or Poisonous Substance ;
=Toxin;
=hemolysin;
|
- 405. Cytarabine/Leucovorin Calcium/Methotrexate/Rituximab
- (UMLS (NCI) C1134698) =Therapeutic or Preventive Procedure ;
| - 453. cytolysis
- [pathologic dissolution or disintegration of cells. ( CSP )] (UMLS (CSP) C1536403) =Cell Function; ;
=Cytotoxicity;
=Autolysis;
bacteriolysis;
Hemolysis;
|
- 406. Cytarabine/Oblimersen
- (UMLS (NCI) C1328115) =Therapeutic or Preventive Procedure; ;
| - 454. CYTOMEGALOVIRAL DISEASE
- [Infection with CYTOMEGALOVIRUS, characterized by enlarged cells bearing intranuclear inclusions. Infection may be in almost any organ, but the salivary glands are the most common site in children, as are the lungs in adults. ( MSH )] (UMLS (ICD9CM) C0010823) =Disease or Syndrome ;
=Herpesviridae disease;
=CMV retinitis;
|
- 407. Cytarabine/UCN-01
- (UMLS (NCI) C0879416) =Therapeutic or Preventive Procedure
| - 455. Cytomegaloviral Pneumonia
- (UMLS (NCI) C0276253) =Disease or Syndrome
|
- 408. Cytarabine/VNP40101M
- (UMLS (NCI) C1328055) =Therapeutic or Preventive Procedure ;
| - 456. Cytomel
- (UMLS (NCI) C0010826) =Amino Acid, Peptide, or Protein; Pharmacologic Substance
|
- 409. cytidine
- [pyrimidine nucleoside that is composed of the base cytosine linked to the five-carbon sugar D-ribose. ( CSP )] (UMLS (CSP) C0010715) =Nucleic Acid, Nucleoside, or Nucleotide; Biologically Active Substance ;
=pyrimidine nucleoside;
ribonucleoside;
cytosine nucleoside;
=4-Amino-1-beta-D-ribofuranosyl-1,3,5-triazin-2(1H)-one;
.beta.-Cytosine arabinoside;
deoxycytidine | - 457. Cytometry
- [The measurement of physical and /or chemical characteristics of cells, or, by extension, of other biological particles. ( NCI )] (UMLS (NCI) C0814048) =Laboratory Procedure
|
- 410. Cytidine Deaminase
- [An enzyme that catalyzes the deamination of cytidine, forming uridine. EC 3.5.4.5. ( MSH )] (UMLS (NCI) C0010723) =Amino Acid, Peptide, or Protein; Enzyme ;
| - 458. Cytopathology
- (UMLS (HL7) C1547979) =Intellectual Product =Diagnostic Service Section ID;
|
- 411. Cytidyl Transferase
- [A family of enzymes that catalyze the transfer of a phosphate group using CTP as the donor molecule (EC 2.7.7.x) ( NCI )] (UMLS (NCI) C1333192) Cytidylyltransferase =Amino Acid, Peptide, or Protein; Enzyme
| - 459. Cytopathology
- [A cytopathologist is an anatomic pathologist trained in the diagnosis of human disease by means of the study of cells obtained from body secretions and fluids, by scraping, washing, or sponging the surface of a lesion, or by the aspiration of a tumor mass or body organ with a fine needle. A major aspect of a cytopathologist's practice is the interpretation of Papanicolaou-stained smears of cells from the female reproductive systems, the "Pap" test. However, the cytopathologist's expertise is applied to the diagnosis of cells from all systems and areas of the body. He/she is a consultant to all medical specialists. A subspecialty certificate was first issued by the ABMS in 1989.ACGME Accredited Residency Program Requirements: None. ( HL7V3.0 )] (UMLS (HL7) C1555817) =Professional or Occupational Group =pathologist;
|
- 412. cytidylate
- [ ] (UMLS (CSP) C0598270) =Nucleic Acid, Nucleoside, or Nucleotide
| - 460. cytopenia
- [A reduction in the number of blood cells. ( NCI )] (UMLS (CSP) C0010828) =Pathologic Function ;
|
- 413. cytidylate kinase
- [ ] (UMLS (CSP) C0056909) =Amino Acid, Peptide, or Protein; Enzyme
| - 461. cytoplasm
- [protoplasm of a cell exclusive of that of the nucleus; it consists of a continuous aqueous solution (cytosol) and the organelles and inclusions suspended in it (phaneroplasm), and is the site of most of the chemical activities of the cell. ( CSP )] (UMLS (CSP) C0010834) =Cell Component ;
=cell component;
=20S Catalytic Proteasome;
caveola |
- 414. cytochalasin
- [group of fungal metabolites that affect the motility of polymorphonuclear leukocytes. ( CSP )] (UMLS (CSP) C0010739) =Pharmacologic Substance; Biologically Active Substance ;
=Fungal Toxin;
| - 462. Cytoplasmic Inclusion
- [Cell substance ( UWDA )] (UMLS (NCI) C0205708) =Cell Component
|
- 415. cytochemistry
- [Branch of histochemistry associated with the localization of cellular components by specific staining methods, as for example the localization of acid phosphatases by the Gomori method. ( NCI )] (UMLS (CSP) C0010741) =Biomedical Occupation or Discipline
| - 463. Cytoplasmic Organelle
- [Cell part which consists of macromolecules aggregated into discrete structures in the protoplasm. (Digital Anatomist Foundational Model) ( NCI )] (UMLS (NCI) C1179962) =Cell Component ;
|
- 416. Cytochlor
- [A radio-sensitizing pyrimidine nucleoside with potential antineoplastic activity. Cytochlor is metabolized first to a phosphate derivative, CldCMP, by the enzyme deoxycytidine kinase and then to the active uracyl derivative, CldUMP, by the enzyme dCMP deaminase; deoxycytidine kinase and dCMP deaminase have been found in abnormally high concentrations in most cancers. CldUMP, the active metabolite, incorporates into DNA and, upon exposure to radiation, induces the formation of uracil radicals and double-strand DNA breaks. (NCI04) ( NCI )] (UMLS (NCI) C1328172) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
| - 464. Cytoplasmic Protein
- [Protein within the interior of the cell; excludes membrane, mitochondrial, and nuclear proteins. ( NCI )] (UMLS (NCI) C1333198) =Amino Acid, Peptide, or Protein; Biologically Active Substance
|
- 417. Cytochlor/Tetrahydrouridine
- (UMLS (NCI) C1328173) =Therapeutic or Preventive Procedure; ;
| - 465. Cytoplasmic Protein Gene
- [Cytoplasmic Protein Genes encode Cytoplasmic Proteins that are typically localized in the cell interior, generally excluding the plasma membrane, mitochondria, and the nucleus. (NCI) ( NCI )] (UMLS (NCI) C1333199) =Gene or Genome ;
|
- 418. cytochrome a
- [A subclass of heme a containing cytochromes that have two imidazole nitrogens as axial ligands and an alpha-band absorption of 605 nm. They are found in a variety of microorganisms and in eucaryotes as a low-spin cytochrome component of MITOCHONDRIAL ELECTRON TRANSPORT COMPLEX IV. ( MSH )] (UMLS (CSP) C0056918) =Amino Acid, Peptide, or Protein; Enzyme
| - 466. Cytoplasmic Protein NCK2
- [Encoded by human NCK2 Gene, ubiquitous 380-aa 43-kDa cytoplasmic NCK Adaptor Protein 2, containing 1 SH2 domain and 3 SH3 domains, associates with tyrosine-phosphorylated growth factor receptors or their substrates. NCK2 interacts with PINCH and DOCK1. NCK2 shares 68% amino acid identity with NCK-alpha; most differences occur outside the SH2/SH3 domains. NCK2 associates with PDGF and EGF receptors via p62DOK and inhibits DNA synthesis. NCK2 binds to B ephrin cytoplasmic domains in a phosphotyrosine-dependent manner. NCK2-dependent (SH2 domain) B ephrin signaling increases FAK activity, redistributes paxillin, inhibits focal adhesions, and disassembles F-actin fibers. NCK2 SH3 domains bind proteins implicated in cytoskeletal regulation: CAP/ponsin, ABI1, dynamin, PAK1, HNRNPK, and axin. (NCI) ( NCI )] (UMLS (NCI) C1334865) GRB4;
NCK Adaptor Protein 2;
NCK-2;
NCKBeta;
SH2/SH3 Adaptor Protein NCK-Beta =Amino Acid, Peptide, or Protein; Biologically Active Substance |
- 419. cytochrome a3
- [A subclass of heme a containing cytochromes with an alpha-band absorption of 605 nm. They are found in a variety of microorganisms and in eukaryotes as a high-spin cytochrome component of MITOCHONDRIAL ELECTRON TRANSPORT COMPLEX IV. ( MSH )] (UMLS (CSP) C1257998) =Amino Acid, Peptide, or Protein; Biologically Active Substance
| - 467. Cytoplasmic Receptor
- [proteins in the cytoplasm or nucleus that specifically bind signaling molecules and trigger changes which influence the behavior of cells; major groups are the steroid hormone receptors, which usually are found in the cytoplasm, and the thyroid hormone receptors, which usually are found in the nucleus; not all cytoplasmic receptors are tree'd under this term. ( CSP )] (UMLS (NCI) C0206587) =Amino Acid, Peptide, or Protein; Receptor =Receptor;
=antigen receptor;
complement receptor;
cytokine receptor |
- 420. cytochrome aa3
- [A dimer of CYTOCHROME A and CYTOCHROME A3. ( MSH )] (UMLS (CSP) C1412005) =Amino Acid, Peptide, or Protein; Enzyme
| - 468. Cytoprotectants
- [Agents administered before, with, or after cancer therapy to reduce or prevent damage or toxicity to the normal cells. (NCI) ( NCI )] (UMLS (NCI) C1268903) Cytoprotective Agent;
Cytoprotective Drugs;
=Pharmacologic Substance; ;
|
- 421. cytochrome b
- [cytochromes of the b group that have alpha-band absorption of 563-564 nm and occur as subunits in mitochondrial electron transport complex III. ( CSP )] (UMLS (CSP) C0010744) =Amino Acid, Peptide, or Protein; Enzyme =CYP;
| - 469. cytoprotection
- [protection of a cell against harm or harmful agents by chemicals or biologicals. ( CSP )] (UMLS (CSP) C0524828) =Physiologic Function ;
=Cytotoxicity;
|
- 422. cytochrome b2
- [do not confuse with LACTATE DEHYDROGENASE, EC 1.1.1.27 and 1.1.1.28. ( CSP )] (UMLS (CSP) C0311584) =Amino Acid, Peptide, or Protein; Enzyme ;
=CYP;
| - 470. Cytosar
- (UMLS (NCI) C0591320) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance; Hazardous or Poisonous Substance
|
- 423. cytochrome b5 reductase
- [A FLAVOPROTEIN oxidoreductase that occurs both as a soluble enzyme and a membrane-bound enzyme due to ALTERNATIVE SPLICING of a single mRNA. The soluble form is present mainly in ERYTHROCYTES and is involved in the reduction of METHEMOGLOBIN. The membrane-bound form of the enzyme is found primarily in the ENDOPLASMIC RETICULUM and outer mitochondrial membrane, where it participates in the desaturation of FATTY ACIDS; CHOLESTEROL biosynthesis and drug metabolism. A deficiency in the enzyme can result in METHEMOGLOBINEMIA. ( MSH )] (UMLS (CSP) C0056921) =Amino Acid, Peptide, or Protein; Enzyme =NAD(P)H oxidoreductase;
| - 471. cytosine analog
- [synthetic or natural chemical compounds which resemble cytosine in structure and/or function. ( CSP )] (UMLS (CSP) C0596400) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance =pyrimidine analog;
=5 methylcytosine;
1(3-hydroxy-2-phosphonomethoxypropyl) Cytosine |
- 424. cytochrome c
- [cytochrome that plays a central role as an electron carrier in the respiration of the mitochondria; contains an iron porphyrin that is the site of electron transfer. ( CSP )] (UMLS (CSP) C0010749) =Amino Acid, Peptide, or Protein; Enzyme =CYP;
| - 472. cytosine deaminase
- [An enzyme which catalyzes the deamination of CYTOSINE resulting in the formation of URACIL. It can also act on 5-methylcytosine to form THYMIDINE. ( MSH )] (UMLS (CSP) C0056997) =Amino Acid, Peptide, or Protein; Enzyme ;
|
- 425. cytochrome c oxidase
- [mitochondrial cytochrome c oxidase is a copper/cytochrome a protein which reduces molecular oxygen to water via superoxide, while oxidizing cytochrome c term may also be used to index other cytochrome oxidases (e.g., o or d of bacteria). ( CSP )] (UMLS (CSP) C0010760) =Amino Acid, Peptide, or Protein; Enzyme =miscellaneous oxidoreductase;
respiratory enzyme | - 473. cytosine nucleoside
- [condensation product of a cystosine base plus a sugar. ( CSP )] (UMLS (CSP) C0596401) =Nucleic Acid, Nucleoside, or Nucleotide ;
=pyrimidine nucleoside;
=.beta.-Cytosine arabinoside;
cytidine;
deoxycytidine;
|
- 426. cytochrome c peroxidase
- [A hemeprotein which catalyzes the oxidation of ferrocytochrome c to ferricytochrome c in the presence of hydrogen peroxide. EC 1.11.1.5. ( MSH )] (UMLS (CSP) C0010796) =Amino Acid, Peptide, or Protein; Enzyme =peroxidase;
| - 474. cytosine nucleotide
- [one of the monomeric units from which DNA or RNA polymers are constructed, consisting of a cytosine base, a pentose sugar, and a phosphate group. ( CSP )] (UMLS (CSP) C0010848) =Nucleic Acid, Nucleoside, or Nucleotide ;
=pyrimidine nucleotide;
|
- 427. cytochrome c reductase
- [A flavoprotein and iron sulfur-containing oxidoreductase that catalyzes the oxidation of NADH to NAD. In eukaryotes the enzyme can be found as a component of mitochondrial electron transport complex I. Under experimental conditions the enzyme can use CYTOCHROME C GROUP as the reducing cofactor. The enzyme was formerly listed as EC 1.6.2.1. ( MSH )] (UMLS (CSP) C0027293) =Amino Acid, Peptide, or Protein; Enzyme ;
| - 475. Cytoskeletal Filament
- (UMLS (NCI) C0010851) =Cell Component ;
|
- 428. cytochrome c6
- [Cytochromes of the c type that are involved in the transfer of electrons from CYTOCHROME B6F COMPLEX and PHOTOSYSTEM I. ( MSH )] (UMLS (CSP) C0111798) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
| - 476. Cytoskeletal Gene
- [Cytoskeletal Genes encode Cytoskeletal Proteins, diverse structural proteins including polymerizable globular subunits (actin, tubulin), "motor ATPases" (myosin, dynein), membrane-supporting linkers (spectrin, clathrin), fibrous proteins (keratin, vimentin), and many more. As constituents of the cytoskeleton, Cytoskeletal Proteins form a flexible cellular framework that provides attachment points for organelles and formed bodies and makes communication between cell parts possible. (NCI) ( NCI )] (UMLS (NCI) C1333200) =Gene or Genome ;
|
- 429. cytochrome cd
- [ ] (UMLS (CSP) C0072546) =Amino Acid, Peptide, or Protein; Enzyme ;
| - 477. cytoskeletal protein
- [diverse family of structural proteins, including polymerizable globular subunits (actin, tubulin), "motor ATPases" (myosin, dynein), membrane-supporting linkers (spectrin, clathrin), fibrous proteins (keratin, vimentin), and many more. ( CSP )] (UMLS (CSP) C0010852) =Amino Acid, Peptide, or Protein; Biologically Active Substance =gene product;
=ABP;
actin;
clathrin;
keratin;
MAP;
spectrin;
tubulin;
vimentin;
ankyrin;
neurofilament protein;
protein 4.1;
myocilin |
- 430. cytochrome f
- [Cytochromes f are found as components of the CYTOCHROME B6F COMPLEX. They play important role in the transfer of electrons from PHOTOSYSTEM I to PHOTOSYSTEM II. ( MSH )] (UMLS (CSP) C0056961) =Amino Acid, Peptide, or Protein; Enzyme
| - 478. cytosol
- [The aqueous part of the cytoplasm within which various particles and organelles are suspended. ( NCI )] (UMLS (CSP) C0010854) =Cell Component ;
|
- 431. Cytochrome P450 2A5
- [Mouse cytochrome P450 2a5 protein (494 aa, 57 kD) is encoded by the mouse Cyp2a5 gene. This enzyme is an unspecific, membrane-bound, monooxygenase located in the endoplasmic reticulum. It catalyzes the metabolism of a variety of substrates including fatty acids, steroids and xenobiotics. ( NCI )] (UMLS (NCI) C0525342) =Amino Acid, Peptide, or Protein; Enzyme ;
| - 479. Cytosolic Protein Tyrosine Phosphastase
- [dephosphorylates O phosphotyrosine groups in phosphoproteins. ( CSP )] (UMLS (NCI) C0085536) =Amino Acid, Peptide, or Protein; Enzyme =phosphatase;
|
- 432. Cytochrome P450 Family Gene
- [Cytochrome P450 Family Genes encode Cytochrome P450 isozymes, hemoprotein components of the mixed-function oxidase system involving electron and/or hydrogen transport through reversible valency change of the heme iron and metabolic biotransformation of substances, including foreign compounds to mutagens and carcinogens. (NCI) ( NCI )] (UMLS (NCI) C1333195) =Gene or Genome ;
| - 480. Cytosolic Protein Tyrosine Phosphatase Gene
- [Non-Receptor Protein Tyrosine Phosphatase Genes encode Non-Receptor Protein Tyrosine Phosphatases, one of the two main categories (soluble and transmembrane receptor) of enzymes that catalyze removal of a tyrosine-attached phosphate group and are important in control of cell growth, proliferation, differentiation, and transformation. Two cysteines in the catalytic domain (one absolutely required for activity) are generally conserved; other conserved residues in the vicinity are important. (NCI) ( NCI )] (UMLS (NCI) C1335055) Non-Receptor Protein Tyrosine Phosphatase Gene;
=Gene or Genome ;
|
- 433. Cytochrome P450 Reductase
- [A flavoprotein that catalyzes the reduction of heme-thiolate-dependent monooxygenases and is part of the microsomal hydroxylating system. Its physiological acceptor is probably cytochrome P-450. EC 1.6.2.4. ( NCI )] (UMLS (NCI) C0027310) =Amino Acid, Peptide, or Protein; Enzyme ;
| - 481. cytosolic receptor
- [ ] (UMLS (CSP) C0872141) =Amino Acid, Peptide, or Protein; Receptor ;
|
- 434. cytocuprein
- [Proteins that protect cells against elevated levels of superoxide a reactive oxygen species. These antioxidant enzymes catalyze the formation of molecular oxygen and hydrogen peroxide from the superoxide anion. They are also potential therapeutic agents in diseases related to oxidative stress and in the regulation of the aging process. ( NCI )] (UMLS (CSP) C0038838) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Enzyme =miscellaneous oxidoreductase;
| - 482. cytospectrophotometry
- [ ] (UMLS (CSP) C0598877) =Research Activity ;
|
- 435. cytodiagnosis
- [diagnosis of the type and, when feasible, the cause of a pathologic process by means of microscopic study of cells in an exudate or other form of body fluid. ( CSP )] (UMLS (CSP) C0010799) =Laboratory Procedure ;
=diagnostic test;
=exfoliative cytology;
cervical smear | - 483. Cytostasan
- (UMLS (NCI) C0057000) =Organic Chemical; Pharmacologic Substance ;
|
- 436. Cytogenetic
- [subdiscipline of genetics which deals with the cytological and molecular analysis of the chromosomes, and location of the genes on chromosomes, and the movements of chromosomes during the cell cycle. ( CSP )] (UMLS (NCI) C0010802) =Biomedical Occupation or Discipline ;
=Genetics;
cytologic technique =Chromosomal;
chromosome complement;
CGH;
karyogram | - 484. Cytotacin
- [novel glioma-mesenchymal extracellular matrix glycoprotein; promotes cell attachment. ( CSP )] (UMLS (NCI) C0076088) =Amino Acid, Peptide, or Protein; Biologically Active Substance =Adhesion Molecule;
Extracellular Matrix Protein |
- 437. Cytogenetic Analysis
- [Techniques for analysis of chromosomal and subchromosomal properties and structures, such as those to diagnose, classify, screen for, or manage genetic diseases and abnormalities. ( NCI )] (UMLS (NCI) C0752095) Cytogenetic Techniques;
=Molecular Biology Research Technique | - 485. Cytotec
- (UMLS (NCI) C0591321) =Eicosanoid; Pharmacologic Substance ;
|
- 438. Cytogenetic Map
- [The visual appearance of a chromosome when stained and examined under a microscope. Particularly important are visually distinct regions, called light and dark bands, which give each of the chromosomes a unique appearance. This feature allows a person's chromosomes to be studied in a clinical test known as a karyotype, which allows scientists to look for chromosomal alterations. (NHGRI Glossary of Genetic Terms) ( NCI )] (UMLS (NCI) C0683225) =Genetic Function ;
| - 486. Cytotechnology
- (UMLS (HL7) C1552390) =Intellectual Product =Specialist/Technologist, Pathology;
|
- 439. cytokeratin
- [Cytokeratins are a family of cysteine-rich fibrous structural proteins that form tough filaments or sheets. These proteins are the main component of intermediate filaments in the epidermis, hair, nails, horny tissues, and the organic matrix of tooth enamel. ( NCI )] (UMLS (CSP) C0010803) =Amino Acid, Peptide, or Protein; Biologically Active Substance
| - 487. Cytotoxic
- [Anticancer drugs that kill cells, especially cancer cells. ( NCI )] (UMLS (NCI) C0677881) =Therapeutic or Preventive Procedure ;
|
- 440. Cytokine
- [soluble factors elaborated by cells of the immune system that act on other cells to regulate their function. ( CSP )] (UMLS (NCI) C0079189) =Amino Acid, Peptide, or Protein; Immunologic Factor =Immunologic Factors;
cell communication molecule =IFN;
IL1;
B cell differentiation factor;
IL7;
lymphokine;
monokine;
hepatocyte growth factor;
Anionic Neutrophil Activating Peptide;
Adipogenesis Inhibitory Factor;
CSIF;
Homolog of Mouse T Cell and Mast Cell Growth Factor 40;
CLMF;
leukemia inhibitory factor;
C-Kit Ligand;
IL13;
chemoattractant cytokine;
IFN-gamma-Inducing Factor;
| - 488. Cytotoxic Lymphocyte Maturation Factor 2, p40
- [This protein is a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggested the role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. (LocusLink) ( NCI )] (UMLS (NCI) C1099914) IL12B;
IL23, subunit p40;
Interkeukin-12 beta chain;
Interleukin 12, p40;
Interleukin 12B;
Interleukin-12B;
Natural Killer Cell Stimulatory Factor-2 =Amino Acid, Peptide, or Protein; Immunologic Factor |
- 441. Cytokine CX2
- [Expressed in activated T cells by human IL17C Gene (IL-17 Family), 197-aa 22-kDa (precursor) secreted cytokine Interleukin-17C (IL17-related) may stimulate release of TNF-alpha and IL-1beta from monocytes in inflammatory immune responses. IL17C differs from IL17 in its pattern of expression, biologic activity, and lack of interaction with IL17 receptor. (NCI) ( NCI )] (UMLS (NCI) C1367171) IL17C;
IL-17C;
IL-21;
Interleukin-17C =Amino Acid, Peptide, or Protein; Immunologic Factor | - 489. cytotoxic lymphocyte reaction
- [ ] (UMLS (CSP) C0598093) =Cell or Molecular Dysfunction ;
|
- 442. Cytokine Gene
- [Cytokines are soluble glycoproteins released by cells of the immune system, which act nonenzymatically through specific receptors to regulate immune responses. Cytokines resemble hormones in that they act at low concentrations and bind with high affinity to a specific receptor. ( NCI )] (UMLS (NCI) C1333196) =Gene or Genome ;
| - 490. Cytotoxic T-Lymphocyte-Associated Serine Esterase 8 Gene
- [This gene is involved in the regulation of osteoclastogenesis and plays a role in rheumatoid arthritis. ( NCI )] (UMLS (NCI) C1334108) IL17;
IL17 Gene;
=Gene or Genome |
- 443. cytokine receptor
- [cell surface proteins that bind cytokines and trigger intracellular changes; postcoordinate with specific cytokine where appropriate. ( CSP )] (UMLS (CSP) C0206552) =Amino Acid, Peptide, or Protein; Immunologic Factor; Receptor =immune receptor;
Cytoplasmic Receptor =Chemokine Receptor;
osteoclastogenesis inhibitory factor;
Receptors, Tumor Necrosis Factor | - 491. Cytotoxic TRAIL Receptor
- [Receptor for Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) ( NCI )] (UMLS (NCI) C1504635) Death Receptor 4;
TNF-Related Apoptosis Inducing Ligand Receptor 1;
TNFRSF10A;
TRAIL Receptor 1;
Tumor Necrosis Factor Receptor Superfamily, Member 10A;
=Amino Acid, Peptide, or Protein; Receptor ;
|
- 444. Cytokine Receptor Gene
- [Cytokine Receptor Genes encode cell surface Cytokine Receptors that bind paracrine or autocrine cytokine growth factors that stimulate humoral and cellular immune responses, as well as activation of phagocytic cells. Cytokines are secreted by inflammatory leukocytes (lymphokines), by monocytes or macrophages (monokines), and by various other cells. Interleukin lymphokines, targeted to cells of hematopoietic origin, are not secreted by leukocytes but affect the cellular responses of leukocytes. (NCI) ( NCI )] (UMLS (NCI) C1333197) =Gene or Genome ;
| - 492. Cytotoxicity
- [Bioassay, Cytotoxicity ( HL7V3.0 )] (UMLS (HL7) C1551412) =Laboratory Procedure =ObservationMethod;
|
- 445. Cytokine Therapy
- (UMLS (NCI) C0199974) =Therapeutic or Preventive Procedure
| - 493. Cytotoxicity
- [relating to or producing a toxic effect on cells. ( CSP )] (UMLS (NCI) C0596402) =Cell or Molecular Dysfunction ;
=Cellular Biology;
=autophagy;
cell death;
cytoprotection;
cytolysis |
- 446. cytokinesis
- [Process in which the cytoplasm of a cell is divided after nuclear division (mitosis) is complete. ( NCI )] (UMLS (CSP) C0010813) =Cell Function ;
| - 494. cytotoxicity test
- [ ] (UMLS (CSP) C0201622) =Laboratory Procedure
|
- 447. cytokinin
- [Plant hormones that promote the separation of daughter cells after mitotic division of a parent cell. Frequently they are purine derivatives. ( MSH )] (UMLS (CSP) C0010815) =Biologically Active Substance ;
| - 495. Cytotrophoblast
- [Trophoblasts with single nucleus and defined cellular structures. As the PLACENTA develops, pockets of cytotrophoblasts serve as stem cells for syncytiotrophoblasts. ( MSH )] (UMLS (NCI) C0230960) =Embryonic Structure
|
- 448. cytologic technique
- [study of cells; their origin, structure, function, behavior, growth and pathology; use this term when emphasis is on a cytologic technique; for other studies see CELL BIOLOGY. ( CSP )] (UMLS (CSP) C1305671) cytology =Laboratory Procedure =Histology;
=cell separation;
Cytogenetic;
Cell/Tissue, Histochemistry;
cell population study;
laser capture microdissection;
subcellular fractionation | - 496. Cytovene
- (UMLS (NCI) C0701307) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
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