[A synthetic 15-methyl analogue of the naturally occurring prostaglandin F2alpha. Carboprost tromethamine induces myometrium smooth muscle contraction by binding to the prostaglandin F2alpha receptors. This drug can be used to induce contractions to end pregnancy or to induce labour and to control severe postpartum bleeding. Due to its contractile effects on gastrointestinal smooth muscle, carboprost tromethamine can cause vomiting and diarrhea. ( NCI )]