[The sodium salt form of cefazolin, a beta-lactam antibiotic and first-generation cephalosporin with bactericidal activity. Cefazolin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis. ( NCI )]
UMLS (NCI) C0700526 - Organic Chemical
- Antibiotic
Relation/PAR: (6R,7R)-3-(((5-Methyl-1,3,4-thiadiazol-2-yl)thio)methyl)-8-oxo-7-(2-(1H-tetrazol-1-yl)acetamido)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid
Relation/CHD: CEFAZOLIN SODIUM 10 GM
CEFAZOLIN SODIUM 10 MG/ML
CEFAZOLIN SODIUM 20 GM/VIL
CEFAZOLIN SODIUM 20 MG/ML
CEFAZOLIN SODIUM 5 GM/VIL
CEFAZOLIN SODIUM 1 GM
CEFAZOLIN SODIUM 500 MG