I I- I0 I1 I2 I3 I4 I5 I6 I7 I8 I9 IA IB IC ID IE IF IG IH II IK IL IM IN IO IP IQ IR IS IT IU IV IX
1,3-Indandione, 2-(p-methoxyphenyl)-
[A synthetic indanedione anticoagulant. Anisindione interferes with the vitamin K-dependent hepatic synthesis of active clotting factors by inhibiting the reduction of vitamin K. This leads to an inhibition of gamma-carboxylation of glutamic acid residues to gamma-carboxyglutamic acid in clotting factors II, VII, IX and X. The consequential effects of this inhibition include a reduced activity of these clotting factors and prolonged blood clotting time. ( NCI )]
UMLS (NCI) C0051919- Organic Chemical
- Pharmacologic Substance
Relation/PAR: [BL100] ANTICOAGULANTS
PHENINDIONE
PHENINDIONE
Relation/CHD: ANISINDIONE 50 MG
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