UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
D D D- D0 D1 D2 D5 D7 D8 D9 DA DB DC DD DE DF DG DH DI DJ DK DL DM DN DO DP DR DS DT DU DV DW DX DY
DI DIA DIB DIC DID DIE DIF DIG DIH DII DIK DIL DIM DIN DIO DIP DIQ DIR DIS DIT DIU DIV DIZ

1,4:3,6-Dianhydro-D-glucitol 5-nitrate

[The mononitrate salt form of isosorbide, an organic nitrate with vasodilator activity. Isosorbide mononitrate relaxes vascular smooth muscle by formation of the free radical nitric oxide (NO), which is identical to the endothelium-derived relaxing factor (EDRF). NO activates guanylyl cyclase, thereby increasing the synthesis of cGMP within smooth muscle, resulting in dephosphorylation of light chain myosin and relaxation of peripheral arteries and veins. In addition, isosorbide mononitrate relaxes coronary arteries, thereby increasing the blood circulation through the ischemic area. (NCI05) ( NCI )]
UMLS (NCI) C0064079
 
Organic Chemical
Pharmacologic Substance
Relation/PAR: ISOSORBIDE
ISOSORBIDE DINITRATE
Relation/CHD: ISOSORBIDE MONONITRATE 120 MG
ISOSORBIDE MONONITRATE 10 MG
ISOSORBIDE MONONITRATE 20 MG
ISOSORBIDE MONONITRATE 60 MG
ISOSORBIDE MONONITRATE 30 MG

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