2(1H)-pyridinone, 4-hydroxy-1-beta-D-ribofuranosyl
[A synthetic analogue of nucleoside uridine lacking a ring nitrogen in the 3-position. 3-deazauridine inhibits cytidine synthase, thereby reducing intracellular levels of cytidine and deoxycytidine and disrupting DNA and RNA synthesis. This agent may trigger apoptosis and enhance differentiation of neoplastic cells.. (NCI04) ( NCI )]
UMLS (NCI) C0000399- Nucleic Acid, Nucleoside, or Nucleotide
- Pharmacologic Substance
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