P P- P0 P1 P2 P3 P4 P5 P6 P7 P8 P9 PA PB PC PD PE PF PG PH PI PK PL PM PN PO PP PQ PR PS PT PU PV PW PX PY
2-(Propylamino)-o-propionotoluidide Hydrochloride
[The hydrochloride salt form of prilocaine, an intermediate-acting local anesthetic of the amide type chemically related to lidocaine. Prilocaine hydrochloride binds to voltage-gated sodium ion channels in the neuronal membrane, thereby preventing the permeability of sodium ions. This leads to a stabilization of the neuronal membrane and inhibits depolarization and results in a reversible blockage of nerve impulse generation and propagation along nerve fibres and subsequent reversible loss of sensation. ( NCI )]
UMLS (NCI) C0008846- Organic Chemical
- Pharmacologic Substance
Relation/PAR: 6,7-Epoxytropine Tropate
Relation/CHD: PRILOCAINE HYDROCHLORIDE 4 %
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