2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide Monohydrochloride

[The hydrochloride salt from of lidocaine, an aminoethylamide and a prototypical member of the amide class anesthetics. Lidocaine interacts with voltage-gated Na+ channels in the nerve cell membrane and blocks the transient increase in permeability of excitable membranes to Na+. This prevents the generation and conduction of nerve impulses and produces a reversible loss of sensation. Lidocaine hydrochloride also exhibits class IB antiarrhythmic effects. The agent decreases the flow of sodium ions into myocardial tissue, especially on the Purkinje network, during phase 0 of the action potential, thereby decreasing depolarization, automaticity and excitability. ( NCI )]

UMLS (NCI) C0546869

Organic Chemical
Pharmacologic Substance

Relation/PAR: [CV300] ANTIARRHYTHMICS
.omega.-Diethylamino-2,6-dimethylacetanilide
[CN204] LOCAL ANESTHETICS, INJECTION
[GU900] GENITOURINARY AGENTS, OTHER

Relation/CHD: LIDOCAINE HCL MISC. POWDER (GM)
LIDOCAINE HYDROCHLORIDE 1 %
LIDOCAINE HYDROCHLORIDE 1 %WV
LIDOCAINE HYDROCHLORIDE 100 MG/ML
LIDOCAINE HYDROCHLORIDE 160 MG
LIDOCAINE HYDROCHLORIDE 2.5 %
LIDOCAINE HYDROCHLORIDE 300 MG
LIDOCAINE HYDROCHLORIDE 4 %
LIDOCAINE HYDROCHLORIDE 10 MG/ML
LIDOCAINE HYDROCHLORIDE 0.5 %
LIDOCAINE HYDROCHLORIDE 5 %
LIDOCAINE HYDROCHLORIDE 1 GM
LIDOCAINE HYDROCHLORIDE 200 MG/ML
LIDOCAINE HYDROCHLORIDE 2 GM
LIDOCAINE HYDROCHLORIDE 2 MG/ML
LIDOCAINE HYDROCHLORIDE 4 MG/ML
LIDOCAINE HYDROCHLORIDE 20 MG/ML
LIDOCAINE HYDROCHLORIDE 1.5 %
LIDOCAINE HYDROCHLORIDE 40 MG/ML
LIDOCAINE HYDROCHLORIDE 8 MG/ML
LIDOCAINE HYDROCHLORIDE 2 %

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