2-Bromo-alpha-ergocryptine Mesylate
[The mesylate salt form of bromocriptine, a semisynthetic, ergot alkaloid with antiparkinson and lactation inhibitory activity. Bromocriptine selectively binds to and activates the postsynaptic dopamine D2-like receptors in the corpus striatum of the central nervous system (CNS). D2-like receptors are coupled to inhibitory G-proteins, which inhibit adenylyl cyclase, thereby preventing signal transduction mediated via cAMP and leading to an inhibitory effect on neurotransmission. This improves Parkinson symptoms, such as dyskinesia. Bromocriptine also has an inhibitory effect on the anterior pituitary gland, which results in blockage of prolactin secretion, thereby suppressing lactation. ( NCI )]
UMLS (NCI) C0546852- Organic Chemical
- Pharmacologic Substance
Relation/PAR: 2-Bromo-alpha-ergocryptine
Relation/CHD: BROMOCRIPTINE MESYLATE 2.5 MG
BROMOCRIPTINE MESYLATE 5 MG
BROMOCRIPTINE MESYLATE 5 MG
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