2-Methyl-4-(4-methyl-1-piperazinyl)-10H-thieno(2,3-b)(1,5)benzodiazepine
[A synthetic derivative of thienobenzodiazepine with antipsychotic properties. As a selective monoaminergic antagonist, olanzapine binds with high affinity binding to the following receptors: serotoninergic, dopaminergic, muscarinic M1-5, histamine H1, and alpha-1-adrenergic receptors; it binds weakly to gamma-aminobutyric acid type A, benzodiazepine, and beta-adrenergic receptors. Although its exact mechanism of action in schizophrenia is unknown, it has been proposed that olanzapine's antipsychotic activity is mediated through a combination of dopamine and serotonin type 2 antagonism. ( NCI )]
UMLS (NCI) C0171023- Organic Chemical
- Pharmacologic Substance
Relation/PAR: Pirenzepine
[CN709] ANTIPSYCHOTICS, OTHER
[CN709] ANTIPSYCHOTICS, OTHER
Relation/CHD: olanzapine 10 MG Disintegrating Tablet
OLANZAPINE 10 MG
OLANZAPINE 2.5 MG
OLANZAPINE 7.5 MG
OLANZAPINE 5 MG
OLANZAPINE 15 MG
OLANZAPINE 20 MG
OLANZAPINE 10 MG
OLANZAPINE 2.5 MG
OLANZAPINE 7.5 MG
OLANZAPINE 5 MG
OLANZAPINE 15 MG
OLANZAPINE 20 MG
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