[The pamoate salt form of hydroxyzine, a synthetic piperazine histamine H1-receptor antagonist with anti-allergic, antispasmodic, sedative, anti-emetic and anti-anxiety properties. Hydroxyzine pamoate blocks the H1 histamine receptor and prevents the symptoms that are caused by histamine activity on capillaries, bronchial smooth muscle, and gastrointestinal smooth muscle, including vasodilatation, increased capillary permeability, bronchoconstriction, and spasmodic contraction of gastrointestinal smooth muscle. In addition, hydroxyzine pamoate crosses the blood-brain barrier and acts on the histamine H1-receptors in the central nervous system. (NCI05) ( NCI )]
UMLS (NCI) C0700539 - Organic Chemical
- Pharmacologic Substance
Relation/PAR: HYDROXYZINE
Relation/CHD: HYDROXYZINE PAMOATE 100 MG
HYDROXYZINE PAMOATE 50 MG
HYDROXYZINE PAMOATE 25 MG/5ML
HYDROXYZINE PAMOATE 25 MG