[A phenazine dye with anti-mycobacterial and anti-inflammatory activity. The exact mechanism through which clofazime exerts its effect is unknown. However, it binds preferentially to mycobacterial DNA, thereby inhibiting DNA replication and cell growth. Clofazimine has a slow bactericidal effect on Mycobacterium leprae and is active against various other Mycobacteria. ( NCI )]
UMLS (NCI) C0008996 - Organic Chemical
- Pharmacologic Substance
- Indicator, Reagent, or Diagnostic Aid
Relation/PAR: phenazine
[AM900] ANTI-INFECTIVES, OTHER
Relation/CHD: CLOFAZIMINE 50 MG